Abstract
This review is focused on the use of the electrochemical techniques, voltammetry and polarography, as well as biosensors, for the study of drug stability. In addition, this review also details the study of drug metabolism by electrochemistry and mass spectrometry. This is used as a tool to mimic drug metabolism and because it is a purely instrumental method, may have advantages over, or be complementary to, the existing biological assays.
Keywords: Drug, stability, metabolism, voltammetry, polarography, biosensors, electrochemistry-mass spectrometry
Combinatorial Chemistry & High Throughput Screening
Title: Stability and Drug Metabolism Assessed by Electrochemical Methods
Volume: 13 Issue: 8
Author(s): Alejandro Alvarez-Lueje and Soledad Bollo Dragnic
Affiliation:
Keywords: Drug, stability, metabolism, voltammetry, polarography, biosensors, electrochemistry-mass spectrometry
Abstract: This review is focused on the use of the electrochemical techniques, voltammetry and polarography, as well as biosensors, for the study of drug stability. In addition, this review also details the study of drug metabolism by electrochemistry and mass spectrometry. This is used as a tool to mimic drug metabolism and because it is a purely instrumental method, may have advantages over, or be complementary to, the existing biological assays.
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Cite this article as:
Alvarez-Lueje Alejandro and Bollo Dragnic Soledad, Stability and Drug Metabolism Assessed by Electrochemical Methods, Combinatorial Chemistry & High Throughput Screening 2010; 13 (8) . https://dx.doi.org/10.2174/138620710791920329
DOI https://dx.doi.org/10.2174/138620710791920329 |
Print ISSN 1386-2073 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5402 |
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