Abstract
In this account we present and critically analyze the different stereoselective synthetic strategies that have been reported in the literature for muricatacins [5-(1-hydroxytridecyl)dihydrofuran-2-ones], naturally occurring δ-hydroxy-γ-lactones related to acetogenins, which display cytotoxic activity towards human tumoral cell lines.
Current Organic Chemistry
Title: Naturally Occurring δ-Hydroxy-γ-Lactones: Muricatacins and Related Compounds
Volume: 14 Issue: 1
Author(s): M. Carmen Murcia, Cristina Navarro, Ana Moreno and Aurelio G. Csaky
Affiliation:
Abstract: In this account we present and critically analyze the different stereoselective synthetic strategies that have been reported in the literature for muricatacins [5-(1-hydroxytridecyl)dihydrofuran-2-ones], naturally occurring δ-hydroxy-γ-lactones related to acetogenins, which display cytotoxic activity towards human tumoral cell lines.
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Cite this article as:
Murcia Carmen M., Navarro Cristina, Moreno Ana and Csaky G. Aurelio, Naturally Occurring δ-Hydroxy-γ-Lactones: Muricatacins and Related Compounds, Current Organic Chemistry 2010; 14 (1) . https://dx.doi.org/10.2174/138527210790226410
DOI https://dx.doi.org/10.2174/138527210790226410 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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