Abstract
The occurrence of 2,6-cyclofarnesanes in Nature is scarce and their presence has been only described in microscopic fungi. However this class of compounds constitutes an interesting group of natural products since they present specific bioactivities. This review moves on to the advances achieved in this kind of structures. These advances are presented in three parts. The first one presents the structure and biological properties of these cyclopentane derivatives. In fact, these compounds could be divided in two groups, namely, chokols, isolated from the stroma of the timothy Phleum pratens inFfected by the endophytic fungus Epicloe typhina, and cyclonerodiol and derivatives, chemically related to chokols, and found to be widespread in fungi. Both, chokols and cyclonerodiol have been described as antifungal, although other biological activities attributed to these compounds are also discussed. The second part considers the biosynthetic studies justifying the formation of cyclonerolidol from cyclization of nerolidyl pyrophosphate. The third and more extended part of the review is devoted to the achievements made in different synthetic strategies directed at some of cyclopentane sesquiterpenes.
Call for Papers in Thematic Issues
Advances of Heterocyclic Chemistry with Pesticide Activity
Global food safety and security will continue to be a global concern for the next 50 years and beyond. Plant diseases have had a significant impact on food safety and security throughout the entire food chain, from primary production to consumption. While conventional chemical pesticides have been traditionally used for ...read more
Calculation design of covalent/metal organic framework based catalysts
This research area combines theoretical computation and screening with machine learning for the design of covalent/metal organic framework-based catalysts, bridging the disciplines of organic chemistry, physical chemistry, computational chemistry, materials science, and machine learning. It covers several critical aspects: designing and synthesizing organic catalysts for improved performance, applying computational methods ...read more
Carbohydrates conversion in biofuels and bioproducts
Biomass pretreatment, hydrolysis, and saccharification of carbohydrates, and sugars bioconversion in biofuels and bioproducts within a biorefinery framework. Carbohydrates derived from woody biomass, agricultural wastes, algae, sewage sludge, or any other lignocellulosic feedstock are included in this issue. Simulation, techno-economic analysis, and life cycle analysis of a biorefinery process are ...read more
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Books
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
Advances in Organic Synthesis
15