Anti-Infective Agents

(Formerly Anti-Infective Agents in Medicinal Chemistry)

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Open Access Articles

Coexistence of Metallo Beta Lactamase Resistant Gene Variants Among Clinical Isolates in Tertiary Care Hospital open Access plus

Volume: 18   Issue: 4
Pp: 429-436
Santhiya K., Jayanthi S.*, Ananthasubramanian M. and Appalaraju B.
DOI:10.2174/2211352518666200121144301

Silica gel Supported Boric tri-Sulfuric Anhydride (SiO2-BTSA): An Efficient Catalytic System for the Synthesis of Phloroglucide Analogs as Antimicrobial Agents open Access plus

Volume: 18   Issue: 4
Pp: 419-428
Rahele Bargebid, Ali Khalafi-Nezhad, Kamiar Zomorodian, Mahkameh Moradi and Soghra Khabnadideh*
DOI:10.2174/2211352517666190902142915

Novel Scaffolds for Leishmania infantum Trypanothione Reductase Inhibitors Derived from Brazilian Natural Products Biodiversity open Access plus

Volume: 18   Issue: 4
Pp: 398-418
Vinícius Guimarães da Paixão and Samuel Silva da Rocha Pita*
DOI:10.2174/2211352518666200131121308

Synthesis and SAR Evaluation of Mercapto Triazolobenzothiazole Derivatives as Anti-tuberculosis Agents open Access plus

Volume: 18   Issue: 4
Pp: 362-374
Mamatha S.V*, S.L. Belagali and Mahesh Bhat
DOI:10.2174/2211352517666191204095558

Synthesis, Characterization and Evaluation of Antioxidant and Antimicrobial activity of Spirochromones Derivatives open Access plus

Volume: 18   Issue: 4
Pp: 352-361
Achut R. Shinde* and Dyanoba B. Muley
DOI:10.2174/2211352518666200117095346

Studies on X-Ray Diffraction, Thermogravimetric Stability, Antibacterial- Antifungal Activity of Fe(II), Ni(II), Cu(II) Metal Chloroquine Complexes Against Bacterial Strains and Fungal Spore open Access plus

Volume: 18   Issue: 4
Pp: 339-351
Mukesh Shankarrao Kadam*, Sachin Atmaram Khiste, Satish Ashruba Dake and Bhimrao Chintamanrao Khade*
DOI:10.2174/2211352517666191021090630

Design, Synthesis and Antimicrobial Activity of Some Triazine Chalcone Derivatives open Access plus

Volume: 18   Issue: 4
Pp: 332-338
Ravindra Sandipan Shinde*, Satish Ashruba Dake and Rajendra Pundalikrao Pawar
DOI:10.2174/2211352517666190710115111

Synthesis, Biological Evaluation and Molecular Docking Study of Pyrazole, Pyrazoline Clubbed Pyridine as Potential Antimicrobial Agents open Access plus

Volume: 18   Issue: 3
Pp: 306-314
Nisheeth C. Desai*, Darshita V. Vaja, Krunalsinh A. Jadeja, Surbhi B. Joshi and Vijay M. Khedkar
DOI:10.2174/2211352517666190627144315

Designing of an Epitope- Based Universal Peptide Vaccine against Highly Conserved Regions in RNA Dependent RNA Polymerase Protein of Human Marburg Virus: A Computational Assay open Access plus

Volume: 18   Issue: 3
Pp: 294-305
S.M. Neaz Mahmud*, Mahbubur Rahman, Antora Kar, Nasreen Jahan and Arif Khan*
DOI:10.2174/2211352517666190717143949

Efficacy of Essential Oil and Hydrosol Extract of Marrubium vulgare on Fungi Responsible for Apples Rot open Access plus

Volume: 18   Issue: 3
Pp: 285-293
Amina Tabet Zatla*, Imane Mami, Mohammed El Amine Dib and Mohammed El Amine Sifi
DOI:10.2174/2211352517666190618105332

Antibacterial Effects of Derivatives of Porphyrin, Naphthalene diimide, Aminophenol and Benzodioxane on Methicillin Resistant Staphylococcus aureus and Neuropathogenic Escherichia coli K1 open Access plus

Volume: 18   Issue: 3
Pp: 275-284
Ruqaiyyah Siddiqui*, Ayaz Anwar, Salwa Ali and Naveed Ahmed Khan
DOI:10.2174/2211352517666190628111232

Hemolysis, Platelet Aggregation and Antibacterial Activities of Human Antiphospholipid Antibody open Access plus

Volume: 18   Issue: 3
Pp: 268-274
Farzaneh Ahmadi Shapoorabadi, Maryam Sadat Mirbagheri Firoozabad*, Neda Habibi and Giti Emtiazi
DOI:10.2174/2211352517666190613111628

Essential Oil Composition and Anti-scabies Potential of Amomum subulatum Roxb. Leaves open Access plus

Volume: 18   Issue: 3
Pp: 261-267
Bharat Sharma, Neeru Vasudeva* and Sunil Sharma
DOI:10.2174/2211352517666190919143631

Phosphonate Derivatives of 3,5-bis(arylidene)-4-piperidone: Synthesis and Biological Evaluation open Access plus

Volume: 18   Issue: 3
Pp: 245-254
Shweta Mishra, Debashree Das, Adarsh Sahu, Shailendra Patil, Ram Kishore Agrawal and Asmita Gajbhiye*
DOI:10.2174/2211352517666190820143735

Polyaminosteroid Analogues as Potent Antibacterial Agents Against Mupirocin- Resistant Staphylococcus aureus Strains open Access plus

Volume: 18   Issue: 3
Pp: 239-244
Adèle Sakr, Fréderic Laurent, Jean-Michel Brunel, Tania Nawfal Dagher, Olivier Blin and Jean-Marc Rolain *
DOI:10.2174/2211352517666190723092347

Antimicrobial Activity of SPC13, New Antimicrobial Peptide Purified from Scolopendra polymorpha Venom open Access plus

Volume: 18   Issue: 3
Pp: 233-238
Rodríguez-Alejandro C.I. and M.C. Gutiérrez *
DOI:10.2174/2211352517666190531110829

Chemical Composition, Antioxidant, Antibacterial, Cytotoxicity, and Hemolyses Activity of Essential Oils from Flower of Matricaria chamomilla var. Chamomilla open Access plus

Volume: 18   Issue: 3
Pp: 224-232
Behnam Mahdavi*, Fereshteh Ghorat, Mahda S. Nasrollahzadeh, Mahmood Hosseyni-Tabar and Hassan Rezaei-Seresht
DOI:10.2174/2211352517666190528114041

Synthetic Methods and Antimicrobial Perspective of Pyrazole Derivatives: An Insight open Access plus

Volume: 18   Issue: 3
Pp: 207-223
Harish Kumar, Kushal Kumar Bansal and Anju Goyal*
DOI:10.2174/2211352517666191022103831

The Role of Gut Microbiota in Antimicrobial Resistance: A Mini-Review open Access plus

Volume: 18   Issue: 3
Pp: 201-206
Farzaneh Firoozeh and Mohammad Zibaei*
DOI:10.2174/2211352517666190716154013

Novel Strategies and Pharmaceutical Agents for the Treatment of Leishmaniasis: A Review open Access plus

Volume: 18   Issue: 2
Pp: 89-100
Mohammad A. Nilforoushzadeh, Maryam Heidari-Kharaji*, Mehrak Zare, Elham Torkamaniha and Sima Rafati
DOI:10.2174/2211352517666190123113843

Synthesis, Biological Evaluation, QSAR, Molecular Docking and ADMET Studies of N-aryl/N,N-dimethyl Substituted Sulphonamide Derivatives open Access plus

Volume: 18   Issue: 2
Pp: 190-199
Samridhi Thakral and Vikramjeet Singh*
DOI:10.2174/2211352517666190902130014

Synthesis and Biological Activity of Some Aminothiazole Derivatives as Antileishmanial Agents open Access plus

Volume: 18   Issue: 2
Pp: 178-189
Zahra Rezaei*, Bahador Sarkari, Soghra Khabnadideh, Mahbobeh Farjami, Mahsa Mehrjou, Atefeh Yazdi, Elham Riazimontazer and Mohammad Fararouei
DOI:10.2174/2211352517666190527112955

Cyclo(L-Pro-L-Tyr) from Streptomyces sp. 150: Exploiting in vitro Potential in Controlling Foodborne Pathogens and Phytopathogens open Access plus

Volume: 18   Issue: 2
Pp: 169-177
Atiqur Rahman*, Shah A. Siddiqui, M. Oliur Rahman and Sun C. Kang*
DOI:10.2174/2211352517666190716155147

Synthesis of piperidine-4-one Derivative Containing Dipeptide: An Acetyl cholinesterase and β-secretase Inhibitor open Access plus

Volume: 18   Issue: 2
Pp: 160-168
Parasuraman Pavadai*, Suresh Ramalingam, Theivendren Panneerselvam, Selvaraj Kunjiappan, Pandurangan Perumal, Vasudevan Mani, Govindaraj Saravanan, Veerachamy Alagarsamy, Damodar Nayak Ammunje and Jithendra Chimakurthy
DOI:10.2174/2211352517666190405155505

Telfairia occidentalis Potentiates the Antiplasmodial Activity of Artemisinins and Amodiaquine Combination Therapy open Access plus

Volume: 18   Issue: 2
Pp: 152-159
Aniekan S. Ebong*, Olorunfemi A. Eseyin, Emmanuel I. Etim, Jude E. Okokon , Victor U. Anah, Emmanuel E. Attih and Goodnews E. Charles
DOI:10.2174/2211352517666190206160812

Assessment of Efficacy and Safety of Clindamycin Against Methicillin- Resistant Staphylococcus aureus (MRSA) Infected Subcutaneous Abscess Model open Access plus

Volume: 18   Issue: 2
Pp: 144-151
Lalitha Vivekanandan*, Hajasherief Sheik, Sengottuvelu Singaravel and Sivakumar Thangavel
DOI:10.2174/2211352517666190301142421

In Silico (3D-QSAR) Designed, Study, Synthesis and Anti-tubercular Evaluation of Pyrazolo-Pyrimidine Derivatives open Access plus

Volume: 18   Issue: 2
Pp: 135-143
Pratiksha Chhatbar, Kaushik Pambhar, Vijay Khedkar, Anamik Shah and Ranjan Khunt*
DOI:10.2174/2211352517666190225143923

Antimicrobial Activity of Some Novel 1-(3-(4-Chlorophenylimino)-3,4- dihydroquinoxalin-2-yl)-3-substituted phenyl-1H-pyrazole-4-carbaldehyde open Access plus

Volume: 18   Issue: 2
Pp: 128-134
Dhanapal Visagaperumal* and Vineeth Chandy
DOI:10.2174/2211352517666190117143604

Tetrahydrocarbazoles as Novel Class of DNA Biosynthesis Inhibitors in Bacteria open Access plus

Volume: 18   Issue: 2
Pp: 121-127
Yan A. Ivanenkov*, Ilya A. Osterman, Ekaterina S. Komarova, Alexey A. Bogdanov, Petr V. Sergiev, Olga A. Dontsova, Alina A. Sofronova, Victor A. Terentiev, Gleb I. Filkov, Renat S. Yamidanov, Alexander G. Majouga, Dmitry S. Bezrukov, Ekaterina V. Deyneka and Dmitry A. Skvortsov
DOI:10.2174/2211352517666181218155259

Effect of Polypropylene Imine Nanocomposite on Gram-Positive and Gram-Negative Bacteria open Access plus

Volume: 18   Issue: 2
Pp: 115-120
Bashir Mohammadpour*, Mohammad A. Boshagh, Bagher Hayati, Leila Farhadi, Hajar Kashefi and Himen Salimizand
DOI:10.2174/2211352517666190215114534

Antibacterial, Antifungal and Anti-tubercular Activities of Chloroform Fraction of the Leaf Extract of Irvingia Gabonensis (African Bush Mango) open Access plus

Volume: 18   Issue: 2
Pp: 109-114
Ifedolapo O. Olanrewaju*, Raphael C. Mordi and JohnBull O. Echeme
DOI:10.2174/2211352517666181122125411

Biological Evaluation of 2-aminothiazole Hybrid as Antimalarial and Antitrypanosomal Agents: Design and Synthesis open Access plus

Volume: 18   Issue: 2
Pp: 101-108
Surender S. Jadav, Vishnu N. Badavath*, Ramesh Ganesan, Narayana M. Ganta, Dominique Besson* and Venkatesan Jayaprakash*
DOI:10.2174/2211352516666181016122537

Development of Usnic Acid Embedded Eudragit Microspheres for Alleviation of Nosocomial Infections open Access plus

Volume: 18   Issue: 1
Pp: 79-87
Shraddha Pandey*, Shashi K. Misra and Nisha Sharma
DOI:10.2174/2211352517666190126161205

Synergistic Effects of Essential Oils of Ammoides verticillata and Satureja candidissima Against Many Pathogenic Microorganisms open Access plus

Volume: 18   Issue: 1
Pp: 72-78
Fatima Benyoucef, Mohammed El Amine Dib*, Boufeldja Tabti, Arrar Zoheir, Jean Costa and Alain Muselli
DOI:10.2174/2211352517666190227161811

Solid State Kinetics, Spectroscopic, Thermal Degradation and Fungicidal Studies of Biodegradable Copper Surfactants Derived from Lauric Acid open Access plus

Volume: 18   Issue: 1
Pp: 59-71
Shilpa Jain, Rashmi Sharma and Arun K. Sharma*
DOI:10.2174/2211352517666190514074750

Immunostimulating Activity of Gold-modified Nanodiamond Particles open Access plus

Volume: 18   Issue: 1
Pp: 54-58
Evgenii Plotnikov*, Skoryk Nina, Savelyev Daniil and Vladimir Plotnikov
DOI:10.2174/2211352517666190328122008

Effect of Chitosan, Chitosan Nanoparticle, Anacyclus pyrethrum and Cyperus rotundus in Combating Plasmid Mediated Resistance in Periodontitis open Access plus

Volume: 18   Issue: 1
Pp: 43-53
Usha Subbiah*, Gokulalakshmi Elayaperumal, Sonaa Elango, Arvind Ramanathan, Bagavad Gita and Karthikeyan Subramani
DOI:10.2174/2211352517666190221150743

Design, Optimization, Synthesis and AntiTB Screening of Benzimidazole Derivatives open Access plus

Volume: 18   Issue: 1
Pp: 24-42
Theivendren Panneerselvam, Selvaraj Kunjiappan, Veerachamy Alagarsamy, Govindaraj Saravanan* and Pavadai Parasuraman
DOI:10.2174/2211352517666190301144054

Punica granatum L. (Pomegranate): A Potential Anti-microbial Agent open Access plus

Volume: 18   Issue: 1
Pp: 2-14
Aida Doostkam, Kamyar Iravani and Shahindokht Bassiri-Jahromi*
DOI:10.2174/2211352517666190215113232

Synthesis, In-Vitro and In-Silico Studies of Benzothiazole Azo-Ester Derivatives as Anti-TB Agents open Access plus

Volume: 18   Issue: 1
Pp: 15-23
Mahesh Bhat* and Shiddappa L. Belagali
DOI:10.2174/2211352517666190126160534

Deboronation of New Clarithromycin-Benzo[c][1,2]oxaborole Conjugates open Access plus

Volume: 17   Issue: 2
Pp: 99-104
Gennady B. Lapa*, Elena B. Isakova, Elena B. Mirchink and Maria N. Preobrazhenskaya
DOI:10.2174/2211352517666181122130101

Structure-Activity Relationship of Dicoumarol Derivatives as anti- Staphylococcus aureus (Staph Infection) Agents open Access plus

Volume: 17   Issue: 2
Pp: 93-98
Nidaa Rasheed*, Natalie J. Galant and Imre G. Csizmadia
DOI:10.2174/2211352516666181112125458

Pharmacological Exploitation of Non-Steroidal Anti-inflammatory Drugs as Potential Sources of Novel Antibacterial Agents open Access plus

Volume: 17   Issue: 2
Pp: 81-92
Ebrahim M. Yimer*, Ousman A. Mohammed and Seid I. Mohammedseid
DOI:10.2174/2211352516666181008114542

Sonic Stimulation and Low Power Microwave Radiation Can Modulate Bacterial Virulence Towards Caenorhabditis elegans open Access plus

Volume: 17   Issue: 2
Pp: 150-162
Priya Patel, Hiteshi Patel, Dhara Vekariya, Chinmayi Joshi, Pooja Patel, Steven Muskal and Vijay Kothari*
DOI:10.2174/2211352516666181102150049

New Trypanosoma cruzi Trypanothione Reductase Inhibitors Identification using the Virtual Screening in Database of Nucleus Bioassay, Biosynthesis and Ecophysiology (NuBBE) open Access plus

Volume: 17   Issue: 2
Pp: 138-149
Nelcí do Carmo Santos, Vinícius G. da Paixão and Samuel S. da Rocha Pita*
DOI:10.2174/2211352516666180928130031

Prophylactic and Therapeutic Treatments' Effect of Moringa Oleifera Methanol Extract on Cryptosporidium Infection in Immunosuppressed Mice open Access plus

Volume: 17   Issue: 2
Pp: 130-137
Nagwa M. El-Sayed* and Ghada M. Fathy
DOI:10.2174/2211352517666181221094420

Synthesis of Some 5-(substituted benzylidene-2, 4-dioxothiazolidin-3-yl) benzoic Acid Derivatives by Conventional and Microwave-assisted Methods and Evaluation of their Potential as Antimicrobial Agents open Access plus

Volume: 17   Issue: 2
Pp: 115-129
Karuna S. Shukla, Shailendra Pandey and Pooja Chawla*
DOI:10.2174/2211352516666181024151213

Synthesis and Evaluation of 3-(1,3-dioxoisoindolin-2-yl)-N-substituted Phenyl Benzamide Analogues as HIV Integrase Strand Transfer Inhibitors open Access plus

Volume: 17   Issue: 2
Pp: 105-114
Pankaj Wadhwa*, Priti Jain, Arpit Patel, Shantanu Shinde and Hemant R. Jadhav
DOI:10.2174/2211352516666181102121920

Anti-mitotic Activity of the Benzothiazole-pyrazole Hybrid Derivatives open Access plus

Volume: 17   Issue: 1
Pp: 66-73
M. Bhat*, S.L. Belagali, N.K.H. Kumar and S. Jagannath
DOI:10.2174/2211352516666180914101758

Design, Synthesis and Biological Profiling of Novel Phenothiazine Derivatives as Potent Antitubercular Agents open Access plus

Volume: 17   Issue: 1
Pp: 50-65
Sushil K. Singh*, Gopal Nath, Ashok Kumar and Satheesh K. Sellamuthu
DOI:10.2174/2211352516666180730121013

Comparison of Minimum Inhibitory Concentration (MIC) value of statin drugs: A Systematic Review open Access plus

Volume: 17   Issue: 1
Pp: 4-19
Meenakshi Gupta and Anoop Kumar*
DOI:10.2174/2211352516666180629124433

Modeling and Statistical Optimization of Culture Conditions for Improvement of Antifungal Compounds Production by Streptomyces albidoflavus S19 Strain of Wastewater Origin open Access plus

Volume: 17   Issue: 1
Pp: 39-49
S. Souagui*, W. Djoudi, H. Boudries, M. Béchet, V. Leclére and M. Kecha
DOI:10.2174/2211352516666180813102424

Novel Diazenyl Containing Phenyl Styryl Ketone Derivatives As Antimicrobial Agents open Access plus

Volume: 17   Issue: 1
Pp: 28-38
L. Sivasankerreddy*, B. Nagamani, T. Rajkumar, M.S. Babu, N.Y. Subbaiah, M.S. Harika and R. Nageswarao
DOI:10.2174/2211352516666180927111546

Synthesis, Screening and Docking Analysis of Novel Benzimidazolium and Benzotriazolium Compounds as Potent Anti Tubercular Agents open Access plus

Volume: 17   Issue: 1
Pp: 20-27
Padma V.S. Guruvelli, Pranita Wagmare, Bhaskar C. Harinath, Risy N. Jamullamudi, Purna N. Kurre and Murali K.K. Muthyala*
DOI:10.2174/2211352516666180810101327

The in vitro Antiviral Mechanisms of Stronger Neo-Minophafen C, an Established Formulation of Compound Glycyrrhizin open Access plus

Volume: 16   Issue: 2
Pp: 136-143
Chi Zhang, Qi-Jie Li, Yi-Li Wang, Jie Chen, Chun-Yan Lv, Wei-Wei Liu, Li Chen, Jia-Yue He, De-Yu Jiang, Xiu-Wen Xia and Wei-Jun Ding*
DOI:10.2174/2211352516666180619142745

Sulfonamides as Inhibitors of Leishmania – Potential New Treatments for Leishmaniasis open Access plus

Volume: 15   Issue: 1
Pp: 57-62
Jade Katinas*, Rachel Epplin, Christopher Hamaker and Marjorie A. Jones
DOI:10.2174/2211352515666170216143401