ISSN (Print): 1877-9123
ISSN (Online): 1877-9131
Volume 5, 2 Issues, 2015
ISSN (Print): 1877-9123
ISSN (Online): 1877-9131
Aims & Scope
EMBASE, Chemical Abstracts, PubsHub, J-Gate, CNKI Scholar, Suweco CZ, EBSCO and Dimensions.
Author(s): Wael AlJaroudi
eISBN: 978-1-60805-088-8, 2010
With the success in the surgical treatment of congenital heart disease, the population of adults with congenital heart disease requiring imaging is soaring. The Role of Imaging in Adults with Congenital Heart Disease: A State-of-the-Art Review is a practical reference guide that covers each major category of congenital heart disease, providing an overview of the diseases as well as specific imaging recommendations for each disease. This Ebook has been written for cardiologists who encounter adults with congenital heart disease in clinical practice as an aid to help these patients with appropriate imaging. Additionally, the Ebook includes numerous color illustrations of the imaging modalities used, as well as a full appendix of additional images. It also includes a summary of the 2008 ACC/AHA Guidelines for Management of Adults with Congenital Heart Disease as a second appendix. It is considered essential reading for practitioners in this field.
Editor(s): Octavian C. Ioachimescu
Guest-Editor(s): Teofilo Lee-Chiong
eISBN: 978-1-60805-267-7, 2011
Contemporary Sleep Medicine should be of interest to a large number of readers interested in sleep medicine. It is divided into two parts – one for patients or simple readers and another for physicians or advanced readers. The Ebook explores new research grounds for sleep disorders. These include novel methodologies for epidemiological research and strategies for curing individuals who suffer from sleep disorders. The volumes seek to update interested readers on the latest advances in the uncharted territory of sleep medicine.
Editor(s): Yves Henrotin
Co-Editor(s): Kim Bennell and Francois Rannou
eISBN: 978-1-60805-317-9, 2012
Osteoarthritis is a chronic disease prevalent among the elderly. Its most prominent feature is the progressive destruction of articular cartilage which results in impaired joint motion, severe pain and ultimately disability. Its prevalence and its impact on daily life pose a significant public health problem. Today, a cure for osteoarthritis remains elusive and the management of the disease is largely palliative, focusing on the alleviation of symptoms. Current recommendations include a combination of pharmacological and non-pharmacological treatments. The term “non-pharmacological” includes physical therapy and rehabilitation, but also nutraceuticals. All guidelines on osteoarthritis management highlight the importance of weight loss and physical activity to improve the functional status of patients. A number of alternative therapies are also commonly suggested by physicians and physiotherapists in their daily practice. The efficacy of these therapies is not evidenced by strong clinical trials. This category includes education, information, electrotherapy, ultrasound, electromagnetic field, spa, hydrotherapy, acupuncture, etc. Non Pharmacological Therapies in the Management of Osteoarthritis reviews the clinical relevance of these therapies and the difficulties in conducting high quality trials assessing their efficacy. This e-book presents supportive scientific evidence for their efficacy and explains the mechanism of action of nutraceuticals targeting osteoarthritis. It also includes many example of exercises, mobilization and manipulation techniques directly useful for medical professionals.
Editor(s): Augusto Azuara-Blanco
Co-Editor(s): Parwez Hossain and Noemi Lois
eISBN: 978-1-60805-133-5, 2012
This E-book provides the reader with a detailed up-to-date review of diagnostic technologies and their role in clinical practice. Chapters are dedicated specifically to describe the role of current technologies in the management of the leading causes of visual impairment such as age-related macular degeneration, diabetic retinopathy, glaucoma, vitreo-retinal disorders, cornea and anterior segment diseases. This E-book will help clinicians to understand and interpret diagnostic tests and critically appraise their performance and limitations. This book is intended for general ophthalmologists and clinicians with a special interest in retinal diseases, glaucoma, anterior segment and cornea. It will also be of interest and value to ophthalmologists in training, scientists, ophthalmic photographers and optometrists.
Editor(s): Eline P. Meulenberg
eISBN: 978-1-60805-264-6, 2012
Antibodies Applications and New Developments is an overview of the current developments of techniques and methods relating to immunodiagnostics and immunoanalysis. This eBook also deals with specialties in the fields of drug, pesticide, antigen and food contaminant detection. The volume is useful for professional immunologists and biotechnologists interested in antibody research and development.
Author(s): Mohammed M.S. Jan
eISBN: 978-1-60805-022-2, 2012
Since the last century, remarkable advances at both the basic and clinical levels have considerably improved our ability to evaluate and treat children with neurological disorders. Many cases seen by general pediatricians are primarily neurological accounting for up to 30% of all consultations to pediatrics with a high ratio of follow-up visits to new patients of about 3:1. This manual is a neurology reference for medical students and pediatric residents and is intended to supplement larger textbooks on pediatric neurology already available. Many of undergraduate medical students refer to deficient and oversimplified references that do not enable them to deal with pediatric neurology patients adequately. The manual presents a simplified, organized, and comprehensive problem based approach to common pediatric neurological disorders directed to the level of medical students, pediatric residents, general practitioners and general pediatricians. This e-book is thus a concise outline with practical tips to facilitate proper diagnosis and management of various neurological disorders.
Editor(s): Kuldip S. Sidhu
eISBN: 978-1-60805-289-9, 2012
Pluripotent stem cells have garnered tremendous interest in recent years, which is primarily driven by the hope of finding a cure for several debilitating human diseases. Cell transplantation (regeneratve medicine) offers considerable therapeutic potential. The procedure employs pluripotent stem cells as these have the inherent ability to reproduce indefinitely and have the ability to produce over 200 different types of cells constituting the human body. The isolation of human embryonic stem cells (hESCs) from embryos and their successful culture in a petri dish in 1998 has been considered as a major breakthrough that is set to shape stem cell research in the 21st century. This has been followed by another remarkable breakthrough in 2006 when scientists demonstrated for the first time that such pluripotent stem cells could be produced from adult somatic tissues without having to use human embryos. These pluripotent stem cells are called the induced pluripotent stem (iPS) cells. Both hESCs and iPS cells - highly versatile cells – could pave the way for alleviating patients suffering from diabetes, Parkinson’s disease, Alzheimer’s disease, and many more.
This eBook brings together the information from the last decade on stem cells, compiled by reputed research experts. Readers will learn all aspects of pluripotent stem cells from basic biology to their use in understanding disease process, toxicology, drug discovery and in developing therapeutic strategies. Research on these cells, including transitional and translational aspects, is explained with the aid of extensive figures, colour photographs, and tables.
This eBook is a valuable resource for undergraduates, postgraduates, scientists, embryologists, tissue engineers, doctors and biomedical scientists interested in stem cell research and medicine.
Editor(s): Julie Lafond and Cathy Vaillancourt
eISBN: 978-1-60805-372-8, 2012
Pregnancy Disorders and Perinatal Outcomes offers readers insights into knowledge related to maternal habits or disorders that could affect fetal development and lead to disability later in childhood and adulthood. It contains chapters on the role of placenta, hormones, stress, nutrition, diabetes, hypertension, in vitro fertilization, obesity, immune systems and epigenetics in pregnancy well-being and perinatal outcomes. This ebook integrates both fundamental and clinical medicine and well as molecular and cell biology. It is written in a multidisciplinary context and would be a handy reference to a wide spectrum of readers including students, clinicians (obstetricians, neonatologists, pediatricians) and basic scientists in gynecology.
Editor(s): Catherine M. Greene
eISBN: 978-1-60805-362-9, 2012
This e-book is a review on current understanding of the role of toll-like receptors (TLRs) in the lung in health and disease. Topics covered include 1) the expression, function and activation of TLRs during bacterial, viral and fungal infection of the airways, 2) the role of TLRs in the pathogenesis of genetic and environmental pulmonary disorders, and 3) TLR biology in lung transplantation. Each chapter highlights recent advances in a selected domain in lung disease research. This e-book serves as a comprehensive resource for both scientists and clinicians studying innate immune mechanisms in the lung and provides a single reference comprising both basic and specialized information.
Editor(s): Adit Ben-Baruch
eISBN: 978-1-60805-256-1, 2012
Tumor development and progression are multi-factorial processes, in which genomic alterations and modifications in gene expression in pre-malignant cells are joined by deleterious microenvironmental factors. The tumor microenvironment contains stroma cells and leukocytes, soluble factors and matrix components. The intensive interplay that exists between the host factors and the tumor cells plays a major role in dictating the final outcome of the malignant process.
Inflammatory mediators are pivotal microenvironmental factors present in the tumor milieu. These inflammatory components support cell growth and invasion, induce mutagenesis, increase angiogenicity, and suppress potential anti-tumor immune functions. The inflammatory constituents that prevail in tumors include leukocytes and soluble mediators - cytokines and chemokines.
This e-book describes the roles played by these mediators in malignancy, and explains the basis for their consideration as therapeutic targets in cancer.
The e-book is a timely overview of the roles played by inflammatory soluble mediators in neoplastic diseases. The topics addressed in this volume serve as a handy reference to investigators studying basic aspects of the malignant tumor growth, to clinicians who wish to better understand the processes involved in malignancy, and to pharmacological professionals seeking novel candidates for therapeutic intervention in cancer.
Editor(s): Vincenzo Parenti Castelli and Marco Troncossi
eISBN: 978-1-60805-439-8, 2012
The technological level of upper limb prostheses has always been fairly poor so far if compared with that of other analogous systems (e.g. lower limb prostheses, assistive robots). However, there is no doubt that in the recent years the upper limb research stimulated the most exciting developments in prosthetic technology. Indeed, new terminal devices and novel articulations for the artificial arm have been recently proposed, and the control hardware, software and firmware are in continuous progress for the implementation of effective control options for the wearers as well as for an easier management of the electronic boards. Also the clinical treatment of the patients is significantly improving. This e-book illustrates significant milestones reached by the scientists in prosthetic research considering both technical issues and clinical features, and also sheds lights on new trends and future developments of this field.
Editor(s): Massimiliano Veroux
Co-Editor(s): Pierfrancesco Veroux
eISBN: 978-1-60805-144-1, 2012
Kidney transplantation is worldwide considered the best replacement therapy in patients with end-stage renal disease. However, although impressive improvements in surgical techniques and in the management of immunosuppression, long-term results have not significantly changed over the last decades.
The purpose of this book is not to be a comprehensive review on kidney transplantation, but it would overview the recent acquisitions in the field of kidney transplantation, by offering to clinicians the future directions and the possible fields of research to improve the long term outcome.
The book is divided into 27 chapters. The first part of the book is devoted to the basic principles of immunity and organ transplantation and the clinical evaluation of potential recipient. Moreover, in this section are discussed the most recent strategies to increase the donor pool trying to offer a kidney transplantation to a growing number of patients. The second part of the book is devoted to the immunosuppression. In these two chapters, the authors present an overview on the immunosuppressive management of kidney transplant recipients, with particular emphasis on the minimization of immunosuppression. The third part of the book is devoted to the complications of immunosuppression and to the psychological aspects of transplantation. This section is particularly detailed, and offers a complete point of view on the consequences and benefits of kidney transplantation. Last section is devoted to the future. The clinical tolerance and xenotransplantation are not still the present, but the authors illustrate the fields of application of these fundamental aspects of organ transplantation.
The authors and editors have tried to select an appropriate mix of citations, but it has not been possible to cite all the relevant articles. Apologies are due to those authors whose works we have failed to cite.
Our goal was to provide the most recent acquisitions in a practical manner. We hope that we have succeeded.
Special thanks to all the authors for their excellent and enthusiastic collaboration and special thanks to our patients to whom are dedicated all our efforts.