Abstract
This paper provides a review on ring closure reactions proceeding via intermediate nitrene formation published during the past 15 years. These cyclisations are classified according to the reaction types taking place. These are nitrene aromatic C-H insertions to form indoles, pyridine rings, nitrene – alicyclic CH insertions to fused oxazolidones, various other insertions on CH bonds in diverse saturated ring and aliphatic chains, nitrene insertion on a methoxy group, addition of the nitrene to a double bond, reactions with intermediate ring formation and subsequent transformation, N-N bond formation by addition of an electrophilic nitrene, and 1,3-dipolar cycloaddition of acyl nitrenes and C=C double bonds.
Keywords: Ring Closures, Heterocycles, Nitrenes, indoles, pyridine rings, N-N bond formation
Current Organic Chemistry
Title: Ring Closures to Heterocycles via Nitrenes
Volume: 13 Issue: 8
Author(s): Gyorgy Hajos and Zsuzsanna Riedl
Affiliation:
Keywords: Ring Closures, Heterocycles, Nitrenes, indoles, pyridine rings, N-N bond formation
Abstract: This paper provides a review on ring closure reactions proceeding via intermediate nitrene formation published during the past 15 years. These cyclisations are classified according to the reaction types taking place. These are nitrene aromatic C-H insertions to form indoles, pyridine rings, nitrene – alicyclic CH insertions to fused oxazolidones, various other insertions on CH bonds in diverse saturated ring and aliphatic chains, nitrene insertion on a methoxy group, addition of the nitrene to a double bond, reactions with intermediate ring formation and subsequent transformation, N-N bond formation by addition of an electrophilic nitrene, and 1,3-dipolar cycloaddition of acyl nitrenes and C=C double bonds.
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Cite this article as:
Hajos Gyorgy and Riedl Zsuzsanna, Ring Closures to Heterocycles via Nitrenes, Current Organic Chemistry 2009; 13 (8) . https://dx.doi.org/10.2174/138527209788167187
DOI https://dx.doi.org/10.2174/138527209788167187 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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