Current Molecular Pharmacology

Oral Administration of the Food-Derived Hydrophilic Antioxidant Ergothioneine Enhances Object Recognition Memory in Mice

Volume: 14   Issue: 2
Pp: 220-233
Noritaka Nakamichi, Shunsuke Nakao, Misa Nishiyama, Yuka Takeda, Takahiro Ishimoto, Yusuke Masuo, Satoshi Matsumoto, Makoto Suzuki and Yukio Kato*
DOI: 10.2174/1874467213666200212102710

Possibility that the Onset of Autism Spectrum Disorder is Induced by Failure of the Glutamine-Glutamate Cycle

Volume: 14   Issue: 2
Pp: 170-174
Koichi Kawada*, Nobuyuki Kuramoto and Seisuke Mimori
DOI: 10.2174/1874467213666200319125109

Polyphenols can Potentially Prevent Atherosclerosis and Cardiovascular Disease by Modulating Macrophage Cholesterol Metabolism

Volume: 14   Issue: 2
Pp: 175-190
Fumiaki Ito*
DOI: 10.2174/1874467213666200320153410

TRPC3-Based Protein Signaling Complex as a Therapeutic Target of Myocardial Atrophy

Volume: 14   Issue: 2
Pp: 123-131
Kazuhiro Nishiyama, Tomohiro Tanaka, Akiyuki Nishimura and Motohiro Nishida*
DOI: 10.2174/1874467213666200407090121

Molecular Mechanisms Involved in the Progression and Protection of Osteoarthritis

Volume: 14   Issue: 2
Pp: 165-169
Yoshifumi Takahata*, Tomohiko Murakami, Kenji Hata and Riko Nishimura
DOI: 10.2174/1874467213666200417122933

Acetate Suppresses Lipopolysaccharide-stimulated Nitric Oxide Production in Primary Rat Microglia but not in BV-2 Microglia Cells

Volume: 14   Issue: 2
Pp: 253-260
Mitsuaki Moriyama*, Yasunori Nishimura, Ryosuke Kurebayashi, Tomoki Minamihata, Kenji Kawabe, Katsura Takano and Yoichi Nakamura
DOI: 10.2174/1874467213666200420101048

Melatonin Receptor as a Drug Target for Neuroprotection

Volume: 14   Issue: 2
Pp: 150-164
Pawaris Wongprayoon and Piyarat Govitrapong*
DOI: 10.2174/1874467213666200421160835

Elimination of the Causes of Poor Sleep Underlying Delirium is a Basic Strategy to Prevent Delirium open access plus

Volume: 14   Issue: 2
Pp: 132-137
Riyo Enomoto and Eibai Lee-Hiraiwa*
DOI: 10.2174/1874467213666200424150709

Interleukin-19 as an Immunoregulatory Cytokine

Volume: 14   Issue: 2
Pp: 191-199
Yasuyuki Fujimoto, Nobuyuki Kuramoto, Masanori Yoneyama and Yasu-Taka Azuma*
DOI: 10.2174/1874467213666200424151528

Protective Potential of Ginkgo biloba Against an ADHD-like Condition

Volume: 14   Issue: 2
Pp: 200-209
Garima Sharma, Naveen Sharma, Bao Trong Nguyen, Ji Hoon Jeong, Seung-Yeol Nah, Yukio Yoneda, Eun-Joo Shin and Hyoung-Chun Kim*
DOI: 10.2174/1874467213666200424152454

Actions of Alcohol in Brain: Genetics, Metabolomics, GABA Receptors, Proteomics and Glutamate Transporter GLAST/EAAT1

Volume: 14   Issue: 2
Pp: 138-149
Mohammed Abul Kashem, Omar Šerý, David V. Pow, Benjamin D. Rowlands, Caroline D. Rae and Vladimir J. Balcar*
DOI: 10.2174/1874467213666200424155244

Chronic Royal Jelly Administration Induced Antidepressant-Like Effects Through Increased Sirtuin1 and Oxidative Phosphorylation Protein Expression in the Amygdala of Mice

Volume: 14   Issue: 2
Pp: 115-122
Thanh Trung Nguyen, Yuki Kambe* and Atsuro Miyata
DOI: 10.2174/1874467213666200424160153

Lactoferrin Suppresses Decreased Locomotor Activities by Improving Dopamine and Serotonin Release in the Amygdala of Ovariectomized Rats open access plus

Volume: 14   Issue: 2
Pp: 245-252
Nobuo Izumo*, Ishibashi Yukiko, Nobuharu Kagaya, Megumi Furukawa, Rina Iwasaki, Akihide Sumino, Kohsuke Hayamizu, Makoto Nakano, Tatsuo Hoshino, Haruna Kurono, Yasuo Watanabe and Takayuki Manabe*
DOI: 10.2174/1570163817666200430002937

Eucommia Leaf Extract Induces BDNF Production in Rat Hypothalamus and Enhances Lipid Metabolism and Aerobic Glycolysis in Rat Liver

Volume: 14   Issue: 2
Pp: 234-244
Hirotaka Oikawa, Shouhei Miyazaki, Rina Kurata, Mutsumi Hattori, Noriko Hayashi, Nami Kawaguchi, Tetsuya Hirata, Taro Ueda and Takahiko Fujikawa*
DOI: 10.2174/1874467213666200505094631

Apelin/Apelin Receptor System: Molecular Characteristics, Physiological Roles, and Prospects as a Target for Disease Prevention and Pharmacotherapy

Volume: 14   Issue: 2
Pp: 210-219
Toshihiko Kinjo, Hiroshi Higashi, Kyosuke Uno and Nobuyuki Kuramoto*
DOI: 10.2174/1874467213666200602133032

Prophylactic Pharmacology for Preemptive Medicine promotion: free to download

Volume: 14   Issue: 2
Pp: 113-114
Yukio Yoneda
DOI: 10.2174/187446721402201231223559

CircRNA 001418 Promoted Cell Growth and Metastasis of Bladder Carcinoma via EphA2 by miR-1297

Volume: 14   Issue: 1
Pp: 68-78
Guorui Peng, Hongxue Meng, Hongxin Pan and Wentao Wang*
DOI: 10.2174/1874467213666200505093815

Anticonvulsant, Anxiolytic and Antidepressant Properties of the β-caryophyllene in Swiss Mice: Involvement of Benzodiazepine-GABAAergic, Serotonergic and Nitrergic Systems

Volume: 14   Issue: 1
Pp: 36-51
George L. da Silva Oliveira*, José C. Correia L. da Silva, Ana P. dos Santos C. L da Silva, Chistiane M. Feitosa and Fernanda R. de Castro Almeida
DOI: 10.2174/1874467213666200510004622

Effects of Galbanic Acid on Proliferation, Migration, and Apoptosis of Glioblastoma Cells Through the PI3K/Akt/MTOR Signaling Pathway

Volume: 14   Issue: 1
Pp: 79-87
Seyed H. Shahcheraghi, Marzieh Lotfi, Mohammad Soukhtanloo, Majid Ghayour-Mobarhan, Hossein Z. Jaliani, Hamid R. Sadeghnia* and Ahmad Ghorbani*
DOI: 10.2174/1874467213666200512075507

Azacitidine, as a DNMT Inhibitor Decreases hTERT Gene Expression and Telomerase Activity More Effective Compared with HDAC Inhibitor in Human Head and Neck Squamous Cell Carcinoma Cell Lines

Volume: 14   Issue: 1
Pp: 60-67
Sepideh Atri, Nikoo Nasoohi and Mahshid Hodjat*
DOI: 10.2174/1874467213666200512080122