ISSN (Print): 1874-4710
ISSN (Online): 1874-4729
Volume 14, 4 Issues, 2021
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ISSN (Print): 1874-4710
ISSN (Online): 1874-4729
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Editor(s): Claudio Santi
eISBN: 978-1-60805-838-9, 2014
The use of organoselenium reagents as catalysts is a common thread that runs through the chapters of this book, introducing important aspects of the modern organoselenium chemistry: organocatalysis, green chemistry, bioinspiration, antioxidant activity. The eBook covers the most recent developments in the classical synthetic application of organoselenium reagents such as electrophilic, nucleophilic and free radical reagents. The volume also features a discussion on the synthesis and the synthetic applications of some emerging classes of selenium compounds such as hypervalent selenium species and selenoamides, and also addresses some biological aspects such as the antimicrobial activity of organoselenium derivatives and the biochemistry of selenoproteins. A number of eminent scientists from different research groups were involved in the preparation of the 13 chapters of the book, making Organoselenium Chemistry: Between Synthesis and Biochemistry an excellent reference about selenium chemistry for researchers and graduate students in the field of selenium chemistry.
Editor(s): John W. Cherwonogrodzky
eISBN: 978-1-60805-878-5, 2014
`Ricin Toxin’ brings together a collection of in depth and cutting edge reviews that focus on the current understanding of ricin toxins. This e-book provides a historical background, innovations in detection, identification and medical countermeasures against this biothreat, and the toxin’s previous use as an anti-cancer agent.
This e-book answers various important questions such as detection of ricin in food or soil, making of humanized antibody against the toxin, novel approaches for the creation of a safe vaccine to protect first responders, exploitation of toxin`s ability to bind and penetrate cells for medical benefits, aftereffects of administering antibody against ricin to a first responder and their exposure to the toxin, neutralization of different ricin from different castor plant cultivars. Aside from learning key concepts that may be overlooked while scanning literature, the reader will benefit from gems of information scattered throughout the book.
The book comprises of five different parts. The first part covers the background of ricin from pharaohs to bioterrorists and beyond.
The second part covers the discovery of recent technologies which are very helpful for the detection of ricin in different matrices, followed by the detection of ricin in the sorption of soils, minerals,textiles, and food; soil inflatration and dust transport. The third part covers the ricin and castor plant cultivars. It also discusses the antibody therapies such as Polyclonal and monoclonal antibodies and the extraction of ricin toxin from several cultivars of the Castor Plant (Ricinus communis).
The fourth part of this e-book discusses different medical countermeasures which are very effective in enhancing the progress in the development of vaccines against ricin intoxication. This part also describes different methods employed for the improvement of anti-ricin antibodies.
The last part of this book describes the replacement and different applications of the toxin. All chapters are written by paramount experts in ricin research.
`Ricin Toxin’ is an essential reading to all medical students, biochemists and professionals involved in the field of toxicology.
Author(s): Mário J. F. Calvete
eISBN: 978-1-68108-124-3, 2016
This reference focuses on defined types of compounds which are of interest to readers who are motivated to explore basic information about new materials for advanced industrial applications. General and established synthetic methodologies for several compounds are explained giving a straightforward approaches for researchers who intend to pursue new projects in materials sciences, This book presents 9 chapters, covering phthalocyanines, polymethines, porphyrins, BODIPYs, dendrimers, carbon allotropes, organic frameworks, nanoparticles and future prospects. Each chapter covers detailed synthetic aspects of the most established preparation routes for the specific compounds, while giving a historical perspective, with selective information on actual and outstanding applications of each material, unraveling what likely might be the future for each category. This book is intended as a hands-on reference guide for undergraduates and graduates interested in industrial chemistry and materials science.
Author(s): Reza Ranjbar-Karimi and Alireza Poorfreidoni
eISBN: 978-981-14-7379-1, 2020
Halogenated pyridines can be used as interesting starting materials in a wide range of organic synthesis methods. Substituted pyridine compounds are used generally as starting materials in the nucleophilic substitution reactions and have unique scaffolds for the construction of other heterocyclic and macrocyclic compounds. They also have important medicinal properties. Due to synthetic difficulties in the synthesis of the highly substituted pyridine derivatives from pyridine itself, perhalopyridines have a special importance in this regard. This book covers the synthetic reactions and applications of perhalopyridines. An introductory chapter introduces the reader to the physical and chemical properties of halopyridines, followed by 3 chapters which focus on pentafluoropyridine, pentachloropyridine and pentabromopyridine, respectively. The focused chapters provide information about synthetic methods and relevant nucleophilic reactions for each of the listed perhalopyridines and their derivatives. The book is a quick reference on perhalopyridines for students of applied chemistry, organic chemistry and chemical engineering.
Author(s): Marcus Vinícius Nora de Souza
eISBN: 978-981-14-8756-9, 2020
Exercises in Organic Synthesis Based on Synthetic Drugs presents information on topics about the synthesis of biologically active compounds which are used against a range of diseases in both humans and animals. Topics are supplemented by notes and exercises for students to stimulate inquiry and learning in the academic environment. Readers will be equipped with basic knowledge of synthetic techniques used in organic chemistry and pharmaceutical research and development.
- Presents information about different techniques and strategies for the synthesis of organic compounds
- Covers a broad range of biologically active compounds
- Easy to read topical presentation
- Exercises, with answers, designed for improving concepts in organic synthesis and medicinal chemistry
- Wide range of bibliographic references for further reading and exercises presented,
Exercises in Organic Synthesis Based on Synthetic Drugs is an essential textbook for students in beginner level courses in organic chemistry, organic synthesis and medicinal chemistry.
Editor(s): Anna Capasso
eISBN: 978-981-14-8974-7, 2021
Both Asia and Africa are home to many plants that can be used for the treatment of many diseases and their medicinal properties are gaining interest in western societies. Medicinal plants from Asia and Africa are used for their healing abilities and also have a symbolic meaning in communities.
The importance of traditional autochthonous plant remedies plays a crucial role in the health of millions of people of these two continents. Even today, traditional medicine represents the dominant medical system for millions of people showing a significant impact on health care practices. Therefore, traditional operators still represent a vital part of regional healthcare systems. For this reason, pharmaceutical industries consider traditional medicine as a source for the identification of bioactive compounds that can be used in the preparation of synthetic drugs.
Biologically Active Natural Products from Asia and Africa: A Selection of Topics guides the reader to information about new natural products from these regions and the different ways to use them to treat or alleviate many of the most common diseases. The volume presents nine topics covering a number of facets of natural product medicine including:
- pharmaceutical analysis of anti-diabetic herbal medicines from Bangladesh and local retailers
- caffeine intake and the risk of female infertility
- pharmaceutical analysis of Urena sinuata (bur mallow)
- anti-CHIKV activities of diterpenes and their derivatives
- anti-inflammatory nanogel for the treatment of psoriasis
- antlithiatic properties of Moroccan medicinal plants
- ethnobotanic, phytochemical and biological activities of Aristolochia longa L. (pipevine)
- wound healing potential of combined extracts of stem bark and leaves of sphenocentrum jollyanum (an African shrub)
This is a handy reference for specialists and R&D experts in pharmaceutical chemistry who wish to be informed about current knowledge on developing natural remedies in Asia and Africa
Author(s): Amin Abbasi, Elham Sheykhsaran and Hossein Samadi Kafil
eISBN: 978-1-68108-838-9, 2021
Postbiotics: Science, Technology, and Applications explains fundamental and applied knowledge about postbiotics. Chapters cover the definition and classification of postbiotics, principal methods for preparing them, information about the main postbiotic constituents and their biological activities and their clinical health benefits. The authors also familiarize the reader with potential applications of postbiotics in the food industry, pharmaceutical chemistry, medicine, and veterinary practice. The text is supported by informative illustrations, tables, and references for further reading. This comprehensive reference, with its emphasis on both basic and applied knowledge, is useful for researchers, academics, veterinarians, and students in the field of microbiology, immunology, pharmacology, biotechnology, food science, and agriculture.