Abstract
Allergic rhinitis (AR) is considered to be multifactorial inflammatory diseases involving complex interactions between genetic and environmental influences. Inflammatory reactions in AR are regulated by many cytokines. The impact of genetic factors on the pathogenesis of AR is currently an area of intense investigation. Various loci and candidate genes have been suggested to underlie allergy. Many or all are still controversial. No significant evidence for linkage to AR has been shown so far, although significant evidence for linkage to various allergic diseases. The aim of this review was to investigate whether the genetic polymorphisms were associated with AR in the literature.
Keywords: Allergic rhinitis, genetic, polymorphism
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Title: Genetic Polymorphism in Allergic Rhinitis
Volume: 7 Issue: 1
Author(s): Yusuf Vayisoglu and Murat Unal
Affiliation:
Keywords: Allergic rhinitis, genetic, polymorphism
Abstract: Allergic rhinitis (AR) is considered to be multifactorial inflammatory diseases involving complex interactions between genetic and environmental influences. Inflammatory reactions in AR are regulated by many cytokines. The impact of genetic factors on the pathogenesis of AR is currently an area of intense investigation. Various loci and candidate genes have been suggested to underlie allergy. Many or all are still controversial. No significant evidence for linkage to AR has been shown so far, although significant evidence for linkage to various allergic diseases. The aim of this review was to investigate whether the genetic polymorphisms were associated with AR in the literature.
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Cite this article as:
Vayisoglu Yusuf and Unal Murat, Genetic Polymorphism in Allergic Rhinitis, Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 2008; 7 (1) . https://dx.doi.org/10.2174/187152308783769195
DOI https://dx.doi.org/10.2174/187152308783769195 |
Print ISSN 1871-5230 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-614X |
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