Drug Metabolism Letters


Zhiyang Zhao
Alliance Pharma
Malvern, PA

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Most Accessed Articles

Effect of Cardiovascular Injury on Catabolism of Adenosine and Adenosine 5-‘Triphosphate in Systemic Blood in a Freely Moving Rat Model In Vivo promotion: free to download

Volume: 10   Issue: 3
Pp: 219-226
Pollen K. Yeung, Shyam S. Kolathuru and Remigius U. Agu
DOI: 10.2174/1872312810666160607013859

Induction of Cytochrome P450 3A by the Ginkgo biloba Extract and Bilobalides in Human and Rat Primary Hepatocytes open Access plus

Volume: 2   Issue: 1
Pp: 60-66
Shu-Feng Zhou, Ying Deng, Hui-chang Bi, Li-zi Zhao, Xue-ding Wang, Jie Chen, Zhi-min Ou, Liang Ding, Le-jia Xu, Su Guan, Xiao Chen and Min Huang
DOI: 10.2174/187231208783478489

Mixed Matrix Method Provides A Reliable Metabolite Exposure Comparison for Assessment of Metabolites in Safety Testing (MIST)

Volume: 11   Issue: 1
Pp: 21-28
Ryan H. Takahashi, Cyrus Khojasteh, Matthew Wright, Cornelis E.C.A. Hop and Shuguang Ma*
DOI: 10.2174/1872312811666170710193229

Formation of a Toxic Quinoneimine Metabolite from Diclofenac: A Quantum Chemical Study open access plus

Volume: 13   Issue: 1
Pp: 64-76
Muthusamy Ramesh* and Prasad V. Bharatam
DOI: 10.2174/1872312812666180913120736

A Practical Perspective on the Evaluation of Small Molecule CNS Penetration in Drug Discovery open access plus

Volume: 13   Issue: 2
Pp: 78-94
Liyue Huang*, Mary C. Wells and Zhiyang Zhao
DOI: 10.2174/1872312813666190311125652

Transport of Bupropion and its Metabolites by the Model CHO and HEK293 Cell Lines open access plus

Volume: 13   Issue: 1
Pp: 25-36
Lyrialle W. Han, Chunying Gao, Yuchen Zhang, Joanne Wang and Qingcheng Mao*
DOI: 10.2174/1872312813666181129101507

A Review of Pharmacokinetic Parameters of Metabolites and Prodrugs

Volume: 7   Issue: 2
Pp: 105-116
Michel Leandro de Campos, Elias Carvalho Padilha and Rosangela Goncalves Peccinini
DOI: 10.2174/1872312808666140317155008

Efficiency in Drug Discovery: Liver S9 Fraction Assay As a Screen for Metabolic Stability open access plus

Volume: 10   Issue: 2
Pp: 83-90
Samantha J. Richardson, April Bai, Ashutosh A. Kulkarni and Mehran F. Moghaddam
DOI: 10.2174/1872312810666160223121836

An Examination of IC50 and IC50-Shift Experiments in Assessing Time-Dependent Inhibition of CYP3A4, CYP2D6 and CYP2C9 in Human Liver Microsomes open Access plus

Volume: 2   Issue: 1
Pp: 51-59
Loren M. Berry and Zhiyang Zhao
DOI: 10.2174/187231208783478407

A Novel Liquid Chromatography Tandem Mass Spectrometry Method for the Estimation of Bilirubin Glucuronides and its Application to In Vitro Enzyme Assays

Volume: 10   Issue: 4
Pp: 264-269
Siva P. Putluru*, Murali K. Matta, Deepak Ahire, Murali Subramanian, Michael Sinz and Sandhya Mandlekar
DOI: 10.2174/1872312810666161124143522