Drug Metabolism Letters


Zhiyang Zhao
Alliance Pharma
Malvern, PA

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Most Accessed Articles

Effect of Cardiovascular Injury on Catabolism of Adenosine and Adenosine 5-‘Triphosphate in Systemic Blood in a Freely Moving Rat Model In Vivo promotion: free to download

Volume: 10   Issue: 3
Pp: 219-226
Pollen K. Yeung, Shyam S. Kolathuru and Remigius U. Agu
DOI: 10.2174/1872312810666160607013859

Induction of Cytochrome P450 3A by the Ginkgo biloba Extract and Bilobalides in Human and Rat Primary Hepatocytes open Access plus

Volume: 2   Issue: 1
Pp: 60-66
Shu-Feng Zhou, Ying Deng, Hui-chang Bi, Li-zi Zhao, Xue-ding Wang, Jie Chen, Zhi-min Ou, Liang Ding, Le-jia Xu, Su Guan, Xiao Chen and Min Huang
DOI: 10.2174/187231208783478489

A Practical Perspective on the Evaluation of Small Molecule CNS Penetration in Drug Discovery open access plus

Volume: 13   Issue: 2
Pp: 78-94
Liyue Huang*, Mary C. Wells and Zhiyang Zhao
DOI: 10.2174/1872312813666190311125652

An Examination of IC50 and IC50-Shift Experiments in Assessing Time-Dependent Inhibition of CYP3A4, CYP2D6 and CYP2C9 in Human Liver Microsomes open Access plus

Volume: 2   Issue: 1
Pp: 51-59
Loren M. Berry and Zhiyang Zhao
DOI: 10.2174/187231208783478407

Mixed Matrix Method Provides A Reliable Metabolite Exposure Comparison for Assessment of Metabolites in Safety Testing (MIST)

Volume: 11   Issue: 1
Pp: 21-28
Ryan H. Takahashi, Cyrus Khojasteh, Matthew Wright, Cornelis E.C.A. Hop and Shuguang Ma*
DOI: 10.2174/1872312811666170710193229

A Comparative Study of the CYP450 Inhibition Potential of Marketed Drugs Using Two Fluorescence Based Assay Platforms Routinely Used in the Pharmaceutical Industry promotion: free to download

Volume: 5   Issue: 1
Pp: 30-39
Mahmud Kajbaf, Raffaele Longhi, Dino Montanari, Federica Vinco, Monica Rigo, Stefano Fontana and Kevin D. Read
DOI: 10.2174/187231211794455262

PREFACE promotion: free to download

Volume: 6   Issue: 1
Pp: 1-1
Chandra Prakash
DOI: 10.2174/187231212800229327

A Review of Pharmacokinetic Parameters of Metabolites and Prodrugs

Volume: 7   Issue: 2
Pp: 105-116
Michel Leandro de Campos, Elias Carvalho Padilha and Rosangela Goncalves Peccinini
DOI: 10.2174/1872312808666140317155008

Efficiency in Drug Discovery: Liver S9 Fraction Assay As a Screen for Metabolic Stability open access plus

Volume: 10   Issue: 2
Pp: 83-90
Samantha J. Richardson, April Bai, Ashutosh A. Kulkarni and Mehran F. Moghaddam
DOI: 10.2174/1872312810666160223121836

Application of a “Fit for Purpose” PBPK Model to Investigate the CYP3A4 Induction Potential of Enzalutamide promotion: free to download

Volume: 10   Issue: 3
Pp: 172-179
Rangaraj Narayanan, Matthew Hoffmann, Gondi Kumar and Sekhar Surapaneni
DOI: 10.2174/1872312810666160729124745