Abstract
Aminoglycoside antibiotics remain to the present date as important chemotherapeutic agents, which have been in clinical use for over 50 years. These antibiotics are multifunctional and have been challenging targets for synthetic chemists. Recent developments in understanding of the mechanism of action and of resistance to these agents have stimulated additional interest in these antibiotics. The present report discussed these efforts in the field for the past few years.
Keywords: Aminoglycoside antibiotics, chemotheraputic agent, Kanamycin B, Neomycine, Gentamicin, deoxystreptamine
Current Organic Chemistry
Title: A Renaissance of Interest in Aminoglycoside Antibiotics
Volume: 5 Issue: 2
Author(s): Lakshmi P. Kotra and Shahriar Mobashery
Affiliation:
Keywords: Aminoglycoside antibiotics, chemotheraputic agent, Kanamycin B, Neomycine, Gentamicin, deoxystreptamine
Abstract: Aminoglycoside antibiotics remain to the present date as important chemotherapeutic agents, which have been in clinical use for over 50 years. These antibiotics are multifunctional and have been challenging targets for synthetic chemists. Recent developments in understanding of the mechanism of action and of resistance to these agents have stimulated additional interest in these antibiotics. The present report discussed these efforts in the field for the past few years.
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Cite this article as:
Kotra P. Lakshmi and Mobashery Shahriar, A Renaissance of Interest in Aminoglycoside Antibiotics, Current Organic Chemistry 2001; 5 (2) . https://dx.doi.org/10.2174/1385272013375698
DOI https://dx.doi.org/10.2174/1385272013375698 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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