Abstract
Bacteriophage lambda has emerged as an alternative vehicle for the surface display of peptides and proteins to the commonly used filamentous phage. There are a number of unique features that make lambda an attractive display vehicle including the ability to display multimeric proteins, no requirement for secretion of the displayed fusion protein and the means to vary the valency of the displayed fusion protein. With its increasing use for cDNA encoded display, the lambda display systems will be an important tool for functional genomics.
Keywords: Bacteriophage Lambda, Cre recombinase, homeobox proteins EMX1, cDNA
Current Pharmaceutical Biotechnology
Title: Bacteriophage Lambda as a Vehicle for Peptide and Protein Display
Volume: 3 Issue: 1
Author(s): Ronald H. Hoess
Affiliation:
Keywords: Bacteriophage Lambda, Cre recombinase, homeobox proteins EMX1, cDNA
Abstract: Bacteriophage lambda has emerged as an alternative vehicle for the surface display of peptides and proteins to the commonly used filamentous phage. There are a number of unique features that make lambda an attractive display vehicle including the ability to display multimeric proteins, no requirement for secretion of the displayed fusion protein and the means to vary the valency of the displayed fusion protein. With its increasing use for cDNA encoded display, the lambda display systems will be an important tool for functional genomics.
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Cite this article as:
Hoess H. Ronald, Bacteriophage Lambda as a Vehicle for Peptide and Protein Display, Current Pharmaceutical Biotechnology 2002; 3 (1) . https://dx.doi.org/10.2174/1389201023378481
DOI https://dx.doi.org/10.2174/1389201023378481 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
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