Current Proteomics

Multi-Epitope Vaccines (MEVs), as a Novel Strategy Against Infectious Diseases

Volume: 17   Issue: 5
Pp: 354-364
Mohammad Mahmoudi Goumari , Ibrahim Farhani, Navid Nezafat and Shirin Mahmoodi*
DOI: 10.2174/1570164617666190919120140

Comparative iTRAQ Proteomic Analysis Provides the Molecular Basis of the Metabolites in Cultivated Glycyrrhiza uralensis and its Wild-Type

Volume: 17   Issue: 5
Pp: 365-378
Chengcheng Wang, Lihong Chen , Zhichen Cai , Sijing Feng , Moyi Yue , Jiaojiao Yang , Lisi Zou and Xunhong Liu *
DOI: 10.2174/1570164617666191004114511

Exploration of Mycelial Proteins from Aspergillus terreus Revealed Ribosome Biogenesis and Antioxidant Enzymes

Volume: 17   Issue: 5
Pp: 433-445
Sonia Kumari Shishodia and Jata Shankar*
DOI: 10.2174/1570164617666191004163734

Inhibition of USP2 Induces Apoptosis through Down Regulation of Fatty Acid Synthase and Cyclin D1 in Triple Negative Breast Cancer

Volume: 17   Issue: 5
Pp: 425-432
Nida Syed, Amber Ilyas, Farha Idrees, Shamshad Zarina and Zehra Hashim *
DOI: 10.2174/1570164617666191008093522

Phosphoproteomic Analysis of Spiroplasma eriocheiris and Crosstalk with Acetylome Reveals the Role of Post-Translational Modifications in Metabolism

Volume: 17   Issue: 5
Pp: 392-403
Peng Liu, Libo Hou, Min Liu, Xuechuan Xu, Qi Gao, Jiewen Deng, Shasha Xiang, Qian Cao, Min Zhou, Quanjie Yang, Wen Wang, Wei Gu* and Qingguo Meng*
DOI: 10.2174/1570164617666191017140456

Exploring PLAC1 Structure and Underlying Mechanisms to Design a Derivative Vaccine Against Breast Cancer Progression; In-Silico Study

Volume: 17   Issue: 5
Pp: 379-391
Farzaneh Afzali, Parisa Ghahremanifard, Mohammad Mehdi Ranjbar and Mahdieh Salimi*
DOI: 10.2174/1570164617666191203111451

Proteomics Analysis of Escherichia coli Treated with Nanosilver: An Approach to Analyze the Bactericidal Action

Volume: 17   Issue: 5
Pp: 404-412
Nafeesa Khatoon, Hammad Alam and Meryam Sardar*
DOI: 10.2174/1570164617666191204125202

A Computational Study to Prevent HIV Invasion by Bovine LF in Mucosal-Layer via Blocking of DC-SIGN_GP120 Interaction

Volume: 17   Issue: 5
Pp: 413-424
Arundhati Banerjee, Rakhi Dasgupta and Sujay Ray*
DOI: 10.2174/1570164617666191206162237

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Volume: 17   Issue: 5
Pp: 353-353
Lei Chen
DOI: 10.2174/157016461705200716110529

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Volume: 17   Issue: 5
Pp: 446-447

DOI: 10.2174/157016461705200716133612

Identifying Ligand-receptor Interactions via an Integrated Fuzzy Model

Volume: 17   Issue: 4
Pp: 287-301
Chang Xu, Yijie Ding, Limin Jiang, Cong Shen, Gaoyan Zhang* and Xuyao Yu*
DOI: 10.2174/1570164616666190306151423

An Integrated Prediction Method for Identifying Protein-Protein Interactions

Volume: 17   Issue: 4
Pp: 271-286
Chang Xu, Limin Jiang, Zehua Zhang, Xuyao Yu, Renhai Chen* and Junhai Xu*
DOI: 10.2174/1570164616666190306152318

Identification of DNA-Binding Proteins by Multiple Kernel Support Vector Machine and Sequence Information

Volume: 17   Issue: 4
Pp: 302-310
Yijie Ding, Feng Chen, Xiaoyi Guo*, Jijun Tang and Hongjie Wu*
DOI: 10.2174/1570164616666190417100509

Computational Methods for Predicting DNA Binding Proteins

Volume: 17   Issue: 4
Pp: 258-270
Gaofeng Pan, Jiandong Wang, Liang Zhao, William Hoskins and Jijun Tang*
DOI: 10.2174/1570164616666190722141129

In Silico Design of Chimeric and Immunogenic Protein-Containing IpaB and IpaD as a Vaccine Candidate against Shigella dysenteriae

Volume: 17   Issue: 4
Pp: 333-341
Seyed Akbar Arianzad, Mehdi Zeinoddini*, Azam Haddadi, Shahram Nazarian and Reza Hasan Sajedi
DOI: 10.2174/1570164617666190906145843

Platelet-Derived Growth Factors (PDGFs) are Key Players in the Stimulation of Airway Smooth Muscle Cells (ASMCs) Alteration in Asthma and Chronic Obstructive Pulmonary Disease (COPD) with Multifarious Inhibitors at an Early Stage of Development

Volume: 17   Issue: 4
Pp: 324-332
Xiaodong Shi and Kwaku Appiah-Kubi*
DOI: 10.2174/1570164617666190906151348

In Silico Identification and Molecular Characterization of Extracellular Cathepsin L Proteases from Giardia duodenalis

Volume: 17   Issue: 4
Pp: 342-351
Sergio A. Durán-Pérez, José G. Rendón-Maldonado*, Lucio de Jesús Hernandez-Diaz, Annete I. Apodaca-Medina, Maribel Jiménez-Edeza and Julio Montes-Avila
DOI: 10.2174/1570164617666191016170628

Distorted Key Theory and its Implication for Drug Development

Volume: 17   Issue: 4
Pp: 311-323
Kuo-Chen Chou*
DOI: 10.2174/1570164617666191025101914

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Volume: 17   Issue: 4
Pp: 255-255
Mustafa Kemal Sezgintürk
DOI: 10.2174/157016461704200514073935

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Volume: 17   Issue: 4
Pp: 256-257
Fei Guo
DOI: 10.2174/157016461704200514074413

Upregulated Retinol Binding Protein and Transthyretin as Predictive Biomarkers of Gestational Diabetes Mellitus

Volume: 17   Issue: 3
Pp: 180-190
Sadaf Ilyas*, Nabila Roohi, Samina Ashraf and Sobia Alyas
DOI: 10.2174/1570164617666190822125837

In Silico Evaluation of the ATP7B Protein: Insights from the Role of Rare Codon Clusters and Mutations that Affect Protein Structure and Function

Volume: 17   Issue: 3
Pp: 213-226
Mojtaba Mortazavi , Abdolrazagh Barzegar *, Abdorrasoul Malekpour*, Mohammad Ghorbani, Saeid Gholamzadeh and Younes Ghasemi
DOI: 10.2174/1570164617666190919114545

Chemoprotective Effects of Propolis on Aflatoxin B1-Induced Hepatotoxicity in Rats: Oxidative Damage and Hepatotoxicity by Modulating TP53, Oxidative Stress

Volume: 17   Issue: 3
Pp: 191-199
Seval Yilmaz*, Fatih Mehmet Kandemir, Emre Kaya and Mustafa Ozkaraca
DOI: 10.2174/1570164617666190925121720

Arecoline Increases the Production of Nitric Oxide and Post-Translational S-Nitrosoproteome in Endothelial Cells

Volume: 17   Issue: 3
Pp: 172-179
Chien-Yi Wu, Wun-Rong Lin, Cherng-Jye Jeng, Chien-Hsing Wu and Bin Huang*
DOI: 10.2174/1570164617666191003112053

Analyzing Structural and Functional Characteristics of Collagenase from Bacillus cereus MH19 via in silico Approaches

Volume: 17   Issue: 3
Pp: 200-212
Shihua Chen, Meihu Ma* and Xing Fu
DOI: 10.2174/1570164617666191004165609

Identification of Drought-Responsive Proteins of Sensitive and Tolerant Tea (Camellia sinensis L) Clones under Normal and Drought Stress Conditions

Volume: 17   Issue: 3
Pp: 227-240
Mehdi Rahimi*, Mojtaba Kordrostami, Mojtaba Mortezavi and Sanam SafaeiChaeikar
DOI: 10.2174/1570164617666191016094142

Characterization of Venoms of Deinagkistrodon acutus and Bungarus multicinctus Using Proteomics and Peptidomics

Volume: 17   Issue: 3
Pp: 241-254
Yaqiong Zhang, Zhiping Jia, Yunyang Liu, Xinwen Zhou and Yi Kong*
DOI: 10.2174/1570164617666191121112319

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Volume: 17   Issue: 3
Pp: 171-171
Fabrizio Ceciliani
DOI: 10.2174/157016461703200219092554

Computational Analysis of Arginine Deiminase Sequences to Provide a Guideline for Protein Engineering

Volume: 17   Issue: 2
Pp: 132-146
Mahboubeh Zarei, Mohammad Reza Rahbar, Navid Nezafat, Manica Negahdaripour, Mohammad Hossein Morowvat and Younes Ghasemi*
DOI: 10.2174/1570164616666190619111852

Interaction of Human Herpesvirus 8 Viral Interleukin-6 with Human Interleukin-6 Receptor Using In Silico Approach: The Potential Role in HHV-8 Pathogenesis

Volume: 17   Issue: 2
Pp: 107-116
Behzad Dehghani, Tayebeh Hashempour* and Zahra Hasanshahi
DOI: 10.2174/1570164616666190626151949

Cell Penetrating Peptide: Sequence-Based Computational Prediction for Intercellular Delivery of Arginine Deiminase

Volume: 17   Issue: 2
Pp: 117-131
Mahboubeh Zarei, Mohammad Reza Rahbar, Manica Negahdaripour, Mohammad Hossein Morowvat, Navid Nezafat* and Younes Ghasemi*
DOI: 10.2174/1570164616666190701120351

Computational Analysis of the Primary and Secondary Structure of Amidases in Relation to their pH Adaptation

Volume: 17   Issue: 2
Pp: 95-106
Neerja Thakur, Nikhil Sharma, Vijay Kumar and Tek Chand Bhalla*
DOI: 10.2174/1570164616666190718150627

Proteomics Study in Urolithiasis

Volume: 17   Issue: 2
Pp: 88-94
Manavi Jain, Paramveer Yadav and Priyadarshini*
DOI: 10.2174/1570164616666190722161823

Genetic and Epigenetic Factors of E3/E3 Genotypes of APO-E Gene as a Strong Predictor for the Diagnosis of Coronary Artery Disease Patients of South India

Volume: 17   Issue: 2
Pp: 147-153
Javeed Ahmad Tantray , Karnati Pratap Reddy , Kaiser Jamil *, Waseem Gul Lone and Shiva Kumar Yerra
DOI: 10.2174/1570164616666190724095158

Antibody Development to HCV Alternate Reading Frame Protein in Liver Transplant Candidate and its Computational Analysis

Volume: 17   Issue: 2
Pp: 154-170
Zahra Musavi, Tayebeh Hashempour*, Javad Moayedi, Behzad Dehghani, Farzaneh Ghassabi, Mehrdad Hallaji, Seyed Younes Hosseini, Ramin Yaghoubi , Siavash Gholami, Mohamad Ali Dehyadegari and Shahin Merat
DOI: 10.2174/1570164617666190822103329

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Volume: 17   Issue: 2
Pp: 87-87
Angela Messina
DOI: 10.2174/157016461702200108152819

Role of Cervical Cancer Radiotherapy in the Expression of EGFR and p53 Gene open access plus

Volume: 17   Issue: 1
Pp: 23-29
Yan Cheng, Kuntian Lan, Xiaoxia Yang, Dongxia Liang, Li Xia and Jinquan Cui*
DOI: 10.2174/1570164616666190204155403

Analysis of Extracellular Proteome of Staphylococcus aureus: A Mass Spectrometry based Proteomics Method of Exotoxin Characterisation

Volume: 17   Issue: 1
Pp: 3-9
Rajdeep Das, Nisha D`souza, Surya K. Choubey, Sethumadhavan Murlidharan, Anura V. Kurpad and Amit K. Mandal*
DOI: 10.2174/1570164616666190204160627

In silico Evaluation of Substrate Binding Site and Rare Codons in the Structure of CYP152A1

Volume: 17   Issue: 1
Pp: 10-22
Mojtaba Mortazavi, Navid Nezafat, Manica Negahdaripour, Mohammad J. Raee, Masoud Torkzadeh-Mahani, Ali Riahi-Madvar and Younes Ghasemi*
DOI: 10.2174/1570164616666190220143131

Evaluation of Luciferase Thermal Stability by Arginine Saturation in the Flexible Loops

Volume: 17   Issue: 1
Pp: 30-39
Farzane Kargar, Mojtaba Mortazavi*, Masoud Torkzadeh-Mahani, Safa Lotfi and Shahryar Shakeri
DOI: 10.2174/1570164616666190320151005

In Silico Study of 1, 4 Alpha Glucan Branching Enzyme and Substrate Docking Studies

Volume: 17   Issue: 1
Pp: 40-50
Farzane Kargar, Amir Savardashtaki*, Mojtaba Mortazavi*, Masoud Torkzadeh Mahani, Ali Mohammad Amani, Younes Ghasemi and Navid Nezafat
DOI: 10.2174/1570164616666190401204009

Varlitinib Mediates Its Activity Through Down Regulating MAPK/EGFR Pathway in Oral Cancer

Volume: 17   Issue: 1
Pp: 51-58
Muhammad Usman, Fariha Tanveer, Amber Ilyas and Shamshad Zarina*
DOI: 10.2174/1570164616666190516114749

Computational Analysis of Therapeutic Enzyme Uricase from Different Source Organisms

Volume: 17   Issue: 1
Pp: 59-77
Anand Kumar Nelapati and JagadeeshBabu PonnanEttiyappan*
DOI: 10.2174/1570164616666190617165107

Structural and Functional Analysis of Mutated Human Pyrin B30.2 Domain

Volume: 17   Issue: 1
Pp: 78-85
Sepideh Parvizpour, Ashraf Fadhil Jomah and Jafar Razmara*
DOI: 10.2174/1570164616666190628165835

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Volume: 17   Issue: 1
Pp: 1-1
Celso Cunha
DOI: 10.2174/157016461701190801112325

Preface promotion: free to download

Volume: 17   Issue: 1
Pp: 2-2
Ajoy Basak
DOI: 10.2174/157016461701190801112656

Isolation, Identification and In Silico Study of Native Cellulase Producing Bacteria

Volume: 17   Issue:
Pp: 1-9
Farzane Kargar, Mojtaba Mortazavi, Mahmood Maleki, Masoud Torkzadeh Mahani, Younes Ghasemi* and Amir Savardashtaki*
DOI: 10.2174/1570164617666191127142035

iTRAQ-based Quantitative Proteomic Analysis of Dural Tissues Reveals Upregulated Haptoglobin to be a Potential Biomarker of Moyamoya Disease

Volume: 17   Issue:
Pp: 1-11
Xiaojun Zhang, Lin Yin, Xiaofang Jia, Yujiao Zhang, Tiefu Liu and Lijun Zhang*
DOI: 10.2174/1570164617666191210103652

Label-Free Mass Spectrometry-Based Plasma Proteomics Identified LY6D, DSC3, CDSN, SERPINB12, and SLURP1 as Novel Protein Biomarkers For Pulmonary Tuberculosis

Volume: 17   Issue:
Pp: 1-12
Xiaoli Yu, Lu Zhang, Na Li, Peng Hu, Zhaoqin Zhu, Wei Wang, Yanzheng Song, Zilu Wen, Hualin Wang and Shulin Zhang*
DOI: 10.2174/1570164617666191210105122

Proteomic Analysis of Differentially Expressed Proteins in Mycobacterium Tuberculosis-Infected Macrophages

Volume: 17   Issue:
Pp: 1-6
Shuang Tian, Dongjun Yang, Qian Long and Min Ling*
DOI: 10.2174/1570164617666191218112128

ABC-Gly: Identifying Protein Lysine Glycation Sites with Artificial Bee Colony Algorithm

Volume: 17   Issue:
Pp: 1-9
Yanqiu Yao, Xiaosa Zhao*, Qiao Ning and Junping Zhou
DOI: 10.2174/1570164617666191227120136

Association of Mutations in the NS5A-PKRBD Region and IFNL4 Genotypes with Hepatitis C Interferon Responsiveness and its Functional and Structural Analysis

Volume: 17   Issue:
Pp: 1-12
Tayebeh Hashempour, Behzad Dehghani, Zahra Mousavi, Tahereh Akbari, Zahra Hasanshahi, Javad Moayedi, Maryam Yahaghi and Mohammad Ali Davarpanah*
DOI: 10.2174/1570164617666200107091124

Physiological and Biochemical Characteristics of Two Soybean Cultivars with Different Seed Vigor During Seed Physiological Maturity

Volume: 17   Issue:
Pp: 1-10
Jiaping Wei, Haihong Zhao , Xiaolin Liu, Sushuang Liu, Linzhi Li and Hao Ma*
DOI: 10.2174/1570164617666200127142051

Comparative Analysis of Skeleton Muscle Proteome Profile between Yak and Cattle Provides Insight into High-Altitude Adaptation

Volume: 17   Issue:
Pp: 1-9
Jin-Wei Xin, Zhi-Xin Chai, Cheng-Fu Zhang, Yu-Mei Yang, Qiang Zhang, Yong Zhu, Han-Wen Cao, Cidan Yang Ji, Jin-Cheng Zhong and Qiu-Mei Ji *
DOI: 10.2174/1570164617666200127151931

Analysis of Oxaliplatin Resistance in Colorectal Cancer Cells by Combined Proteomics and Phosphoproteomic

Volume: 17   Issue:
Pp: 1-10
Rui Yang, Kunli Feng, Yanhong Cao, Hao Wang and Baolong Wang*
DOI: 10.2174/1570164617666200225123903

Proteomic Analysis of the Vitreous Body in Proliferative and Non-Proliferative Diabetic Retinopathy

Volume: 17   Issue:
Pp: 1-10
Van-An Duong, Jeeyun Ahn, Na-Young Han, Jong-Moon Park, Jeong-Hun Mok, Tae Wan Kim and Hookeun Lee*
DOI: 10.2174/1570164617666200302101442

Soy Protein Remnants Digested by Gastro-duodenal Proteases can Alter Microbial Interactions and Intestinal Cholesterol Absorption

Volume: 17   Issue:
Pp: 1-12
Jinkyu Lim *, Juyoung Lee , Yujin Yum , Sung-hee Kim and Dorsilla Anono Katimbwa
DOI: 10.2174/1570164617666200305113924

Analysis of the Non-Specific Binding Proteins in the RNA Pull-Down Experiment

Volume: 17   Issue:
Pp: 1-7
Yongmei Li*, Baicai Yang, Yali Zhang, Kaiwen Hei and Mingming Xiao
DOI: 10.2174/1570164617666200319143539

Computer-Aided Design of a Novel Poly-Epitope Protein in Fusion with an Adjuvant as a Vaccine Candidate Against Leptospirosis

Volume: 17   Issue:
Pp: 1-11
Ehsan Rashidian*, Ali Forouharmehr, Narges Nazifi , Amin Jaydari and Nemat Shams
DOI: 10.2174/1570164617666200319144331

A Multi-Method and Structure-Based In Silico Vaccine Designing Against Helicobacter pylori Employing Immuno-Informatics Approach

Volume: 17   Issue:
Pp: 1-11
Anam Naz*, Tahreem Zaheer, Hamza Arshad Dar, Faryal Mehwish Awan, Ayesha Obaid, Shifa Tariq Ashraf, Rehan Zafar Paracha, Arif Malik and Amjad Ali
DOI: 10.2174/1570164617999200414120231

High-Sensitivity C-Reactive Protein and Lipoprotein-Associated Phospholipase A2 in Predicting Recurrence and Severity of Stenosis in Symptomatic Intracranial Atherosclerotic Disease

Volume: 17   Issue:
Pp: 1-6
Soumya Krishnamoorthy , Deepa Damayanthi, Srinivas Gopala, Rejith Paul and P. N. Sylaja*
DOI: 10.2174/1570164617666200414123848

Impact of Liver Cancer Somatic Mutations on Protein Structures and Functions

Volume: 17   Issue:
Pp: 1-8
Amna Amin Sethi and Nisar Ahmed Shar*
DOI: 10.2174/1570164617666200415155637

Proteomic Investigations to Assess the Impact of Salinity on Vigna radiata L. Genotypes open access plus

Volume: 17   Issue:
Pp: 1-7
Hesham F. Alharby and Khalid Rehman Hakeem*
DOI: 10.2174/1570164617999200420075125

Bioinformatics-based Identification of Proteins Expressed by Arthropod- borne Viruses Transmitted by Aedes Aegypti Mosquito

Volume: 17   Issue:
Pp: 1-14
Carlos Polanco*, Vladimir N. Uversky, Alberto Huberman, Leire Andrés, Thomas Buhse, Jorge-Alberto Castañón-González and Alma-Fernanda Sánchez-Guerrero
DOI: 10.2174/1570164617999200422123618

Prediction of Prophylactic Peptide Vaccine Candidates for Human Papillomavirus (HPV): Immunoinformatics and Reverse Vaccinology Approaches

Volume: 17   Issue:
Pp: 1-15
Mehreen Ismail, Zureesha Sajid, Amjad Ali, Xiaogang Wu, Syed Aun Muhammad* and Rehan Sadiq Shaikh
DOI: 10.2174/1570164617999200505095802

Subtype Classification by Polymerase and Gag Genes of HIV-1 Iranian Sequences Registered in the NCBI GenBank

Volume: 17   Issue:
Pp: 1-9
Behzad Dehghani, Zahra Hasanshahi, Tayebeh Hashempour* and Parvin Afsar Kazerooni
DOI: 10.2174/1570164617999200510233018

Presence of Cathelicidin-1 in Milk as an Indicator of the Severity of Mammary Infection in Ewes

Volume: 17   Issue:
Pp: 1-7
Angeliki I. Katsafadou, Natalia G.C. Vasileiou, George T. Tsangaris, Katerina S. Ioannidi, Athanasios K. Anagnostopoulos, Charalambos Billinis, Ilektra A. Fragkou, Elias Papadopoulos, Vasia S. Mavrogianni, Dafni T. Lianou, Dimitris C. Chatzopoulos and George C. Fthenakis*
DOI: 10.2174/1570164617999200510234638

In Silico Structural and Functional Analyses of Bacillus Uricases

Volume: 17   Issue:
Pp: 1-19
Anand Kumar Nelapati, Shubham Meena, Aditya Kumar Singh, Narsimha Bhakta and JagadeeshBabu PonnanEttiyappan*
DOI: 10.2174/1570164617999200512081127

Comparative Studies on Phospholipase A2 as a Marker for Gut Microbiota- liver-brain Axis in a rodent Model of Autism

Volume: 17   Issue:
Pp: 1-9
Abeer Al-Dbass, Abir Ben Bacha, Nadine MS Moubayed, Ramesa Shafi Bhat, Manar Al-Mutairi, Osima M. Alnakhli, Majidh Al-Mrshoud, Hanan Alfawaz, Maha Daghestani and Afaf El-Ansary*
DOI: 10.2174/1570164617999200519100634

RNA-Seq Data Analysis Unveils Potential Conserved Micro-RNAs in Agave Deserti

Volume: 17   Issue:
Pp: 1-16
Basit Jabbar, Batcho Agossa Anicet, Muhammad Bilal Sarwar, Bushra Rashid*, Sameera Hassan and Tayyab Husnain
DOI: 10.2174/1570164617999200529122637

Physio-Morphology and Proteomic Attitude of Ziziphus Spina-Christi in Copper-Contaminated Sites in Saudi Arabia: Is It a Candidate Bioremediator?

Volume: 17   Issue:
Pp: 1-14
Modhi O. Alotaibi, Afrah E. Mohammed*, Taghreed A. Almutairi, Zakia Shinwari, Ayodele Alaiya and Mudawi M. Elobeid
DOI: 10.2174/1570164617999200612114626