CNS & Neurological Disorders - Drug Targets

Transdermal Drug Delivery Systems and their Potential in Alzheimer’s Disease Management

Volume: 19   Issue: 5
Pp: 360-373
Panoraia I. Siafaka, Ece Ö. Bülbül, Gökce Mutlu, Mehmet E. Okur, Ioannis D. Karantas and Neslihan Ü. Okur*
DOI: 10.2174/1871527319666200618150046

Autoimmune Encephalitis: Current Knowledge on Subtypes, Disease Mechanisms and Treatment

Volume: 19   Issue: 8
Pp: 584-598
Mette Scheller Nissen, Matias Ryding, Morten Meyer and Morten Blaabjerg*
DOI: 10.2174/1871527319666200708133103

Current Strategies and Novel Drug Approaches for Alzheimer Disease

Volume: 19   Issue: 9
Pp: 676-690
Roma Ghai*, Kandasamy Nagarajan, Meenakshi Arora, Parul Grover, Nazakat Ali and Garima Kapoor
DOI: 10.2174/1871527319666200717091513

Overview of Therapeutic Drugs and Methods for the Treatment of Parkinson’s Disease

Volume: 19   Issue: 3
Pp: 195-206
Andrew Schneider, Adam T. Sari, Hasan Alhaddad and Youssef Sari*
DOI: 10.2174/1871527319666200525011110

Targeting the PI3K/AKT/mTOR Signaling Pathway in Primary Central Nervous System Lymphoma: Current Status and Future Prospects

Volume: 19   Issue: 3
Pp: 165-173
Xiaowei Zhang and Yuanbo Liu *
DOI: 10.2174/1871527319666200517112252

Evidence on the New Drug Lumateperone (ITI-007) for Psychiatric and Neurological Disorders

Volume: 19   Issue: 4
Pp: 243-247
Marianna Mazza*, Giuseppe Marano, Gianandrea Traversi, Gabriele Sani and Luigi Janiri
DOI: 10.2174/1871527319666200601145653

The β-Secretase Enzyme BACE1: A Biochemical Enigma for Alzheimer’s Disease

Volume: 19   Issue: 3
Pp: 184-194
Hirak Shah, Ashish Patel*, Vruti Parikh, Afzal Nagani, Bhargav Bhimani, Umang Shah and Tushar Bambharoliya
DOI: 10.2174/1871527319666200526144141

Management of Impulse Control Disorders with Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease open access plus

Volume: 19   Issue: 8
Pp: 611-617
Deborah Amstutz, Steffen Paschen, Martin Lenard Lachenmayer, Marie Elise Maradan-Gachet, Günther Deuschl, Paul Krack and Ines Debove*
DOI: 10.2174/1871527319666200720105553

In Vitro and In Vivo Neuroprotective Effects of Etifoxine in β-Amyloidinduced Toxicity Models

Volume: 19   Issue: 3
Pp: 227-240
Veronique Riban *, Johann Meunier , Dorothee Buttigieg, Vanessa Villard and Marc Verleye
DOI: 10.2174/1871527319666200601151007

Levodopa Therapy for Parkinson's Disease: History, Current Status and Perspectives

Volume: 19   Issue: 8
Pp: 572-583
Helle Bogetofte, Arezo Alamyar, Morten Blaabjerg and Morten Meyer*
DOI: 10.2174/1871527319666200722153156

Interlink Between Insulin Resistance and Neurodegeneration with an Update on Current Therapeutic Approaches

Volume: 19   Issue: 3
Pp: 174-183
Subrat Kumar Bhattamisra*, Lee Yuen Shin, Hanis Izzati Binti Mohd Saad, Vikram Rao, Mayuren Candasamy, Manisha Pandey and Hira Choudhury
DOI: 10.2174/1871527319666200518102130

The Combination of rTMS and Pharmacotherapy on In Vitro Models: A Mini-Review

Volume: 19   Issue: 3
Pp: 220-226
Chryssa Pourzitaki*, Ioannis Dardalas, Frideriki Poutoglidou, Dimitrios Kouvelas and Vasilios K. Kimiskidis
DOI: 10.2174/1871527319666200518100716

A Pivotal Role of the Nrf2 Signaling Pathway in Spinal Cord Injury: A Prospective Therapeutics Study

Volume: 19   Issue: 3
Pp: 207-219
Saeed Samarghandian, Ali Mohammad Pourbagher-Shahri, Milad Ashrafizadeh, Haroon Khan, Fatemeh Forouzanfar, Hamed Aramjoo and Tahereh Farkhondeh*
DOI: 10.2174/1871527319666200604175118

The locus of Action of CGRPergic Monoclonal Antibodies Against Migraine: Peripheral Over Central Mechanisms

Volume: 19   Issue: 5
Pp: 344-359
Abimael González-Hernández, Bruno A. Marichal-Cancino, Enrique García-Boll and Carlos M. Villalón*
DOI: 10.2174/1871527319666200618144637

Inflammation and Mitochondrial Dysfunction in Autism Spectrum Disorder

Volume: 19   Issue: 5
Pp: 320-333
Maria Gevezova, Victoria Sarafian*, George Anderson and Michael Maes
DOI: 10.2174/1871527319666200628015039

When Sick Brain and Hopelessness Meet: Some Aspects of Suicidality in the Neurological Patient open access plus

Volume: 19   Issue: 4
Pp: 257-263
Alessandra Costanza*, Andrea Amerio, Andrea Aguglia, Andrea Escelsior, Gianluca Serafini, Isabella Berardelli, Maurizio Pompili and Mario Amore
DOI: 10.2174/1871527319666200611130804

Design and Microwave-Assisted Synthesis of Aza-Resveratrol Analogs with Potent Cholinesterase Inhibition

Volume: 19   Issue: 8
Pp: 630-641
Brunella Biscussi, Victoria Richmond, Carlos Javier Baier, Pau Arroyo Mañez and Ana Paula Murray*
DOI: 10.2174/1871527319666200905121536

Metabolic Adjustments by LncRNAs in Peripheral Neutrophils Partly Account for the Complete Compensation of Asymptomatic MMD Patients

Volume: 19   Issue: 4
Pp: 306-317
Ziping Han, Lingzhi Li, Ping Liu, Yuyou Huang, Sijia Zhang, Guangwen Li, Fangfang Li, Haiping Zhao, Zhen Tao, Rongliang Wang, Qingfeng Ma* and Yumin Luo*
DOI: 10.2174/1871527319666200618150827

Impact of Cannabis-Based Medicine on Alzheimer’s Disease by Focusing on the Amyloid β-Modifications: A Systematic Study

Volume: 19   Issue: 5
Pp: 334-343
Tahereh Farkhondeh, Haroon Khan, Michael Aschner, Fariborz Samini, Ali M. Pourbagher-Shahri, Hamed Aramjoo, Babak Roshanravan, Christopher Hoyte, Omid Mehrpour and Saeed Samarghandian*
DOI: 10.2174/1871527319666200708130745