CNS & Neurological Disorders - Drug Targets

Formerly Current Drug Targets - CNS & Neurological Disorders


Edoardo Spina
Department of Clinical and Experimental Medicine
University of Messina
Policlinico Universitario
Via Consolare Valeria

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Volume: 9 Issue: 3, July

Commentary (Research Highlights)

Volume:9   Issue: 3
Pp: 257-257
Stephen D. Skaper
DOI: 10.2174/187152710791292611
Published on: 01 March, 2012

Editorial [Hot topic: Neuroprotection in ALS: From Pathology to Treatment (Guest Editors: Gabriele Siciliano and Luigi Murri)]

Volume:9   Issue: 3
Pp: 258-258
Luigi Murri
DOI: 10.2174/187152710791292675
Published on: 01 March, 2012

Neuronal Death in Amyotrophic Lateral Sclerosis (ALS): What Can We Learn from Genetics?

Volume:9   Issue: 3
Pp: 259-267
J. Sreedharan
DOI: 10.2174/187152710791292558
Published on: 01 March, 2012

The Role of Autophagy: What can be Learned from the Genetic Forms of Amyotrophic Lateral Sclerosis

Volume:9   Issue: 3
Pp: 268-278
Livia Pasquali, Riccardo Ruffoli, Federica Fulceri, Sara Pietracupa, Gabriele Siciliano, Antonio Paparelli and Francesco Fornai
DOI: 10.2174/187152710791292594
Published on: 01 March, 2012

Histone Deacetylation and Motor Neuron Degeneration

Volume:9   Issue: 3
Pp: 279-284
S. Schmalbach and S. Petri
DOI: 10.2174/187152710791292684
Published on: 01 March, 2012

Protein Aggregation and Defective RNA Metabolism as Mechanisms for Motor Neuron Damage

Volume:9   Issue: 3
Pp: 285-296
N. Ticozzi, A. Ratti and V. Silani
DOI: 10.2174/187152710791292585
Published on: 01 March, 2012

Amyotrophic Lateral Sclerosis and Excitotoxicity: From Pathological Mechanism to Therapeutic Target

Volume:9   Issue: 3
Pp: 297-304
E. Bogaert, C. d'Ydewalle and L. Van Den Bosch
DOI: 10.2174/187152710791292576
Published on: 01 March, 2012

Clinical Trials for Neuroprotection in ALS

Volume:9   Issue: 3
Pp: 305-313
G. Siciliano, C. Carlesi, L. Pasquali, S. Piazza, S. Pietracupa, F. Fornai, S. Ruggieri and L. Murri
DOI: 10.2174/187152710791292648
Published on: 01 March, 2012

Stem Cells in Amyotrophic Lateral Sclerosis: Motor Neuron Protection or Replacement?

Volume:9   Issue: 3
Pp: 314-324
V. Silani, C. Calzarossa, L. Cova and N. Ticozzi
DOI: 10.2174/187152710791292666
Published on: 01 March, 2012

Involvement of Immune Response in the Pathogenesis of Amyotrophic Lateral Sclerosis: A Therapeutic Opportunity?

Volume:9   Issue: 3
Pp: 325-330
A. Calvo, C. Moglia, M. Balma and A. Chio
DOI: 10.2174/187152710791292657
Published on: 01 March, 2012

Repetitive Transcranial Magnetic Stimulation for ALS

Volume:9   Issue: 3
Pp: 331-334
M. Dileone, P. Profice, F. Pilato, F. Ranieri, F. Capone, G. Musumeci, L. Florio, R. Di Iorio and V. Di Lazzaro
DOI: 10.2174/187152710791292620
Published on: 01 March, 2012

Recent Therapeutic Advances for Treating Medulloblastoma: Focus on New Molecular Targets

Volume:9   Issue: 3
Pp: 335-348
A.L. Schmidt, A.L. Brunetto, G. Schwartsmann, R. Roesler and A.L. Abujamra
DOI: 10.2174/187152710791292602
Published on: 01 March, 2012

Glia as a Turning Point in the Therapeutic Strategy of Parkinsons Disease

Volume:9   Issue: 3
Pp: 349-372
Francesca L'Episcopo, Cataldo Tirolo, Nuccio Testa, Salvo Caniglia, Maria Concetta Morale and Bianca Marchetti
DOI: 10.2174/187152710791292639
Published on: 01 March, 2012

Mechanisms of Oxidative Glutamate Toxicity: The Glutamate/Cystine Antiporter System xc¯ as a Neuroprotective Drug Target

Volume:9   Issue: 3
Pp: 373-382
Philipp Albrecht, Jan Lewerenz, Sonja Dittmer, Rebecca Noack, Pamela Maher and Axel Methner
DOI: 10.2174/187152710791292567
Published on: 01 March, 2012