CNS & Neurological Disorders - Drug Targets

Formerly Current Drug Targets - CNS & Neurological Disorders


Edoardo Spina
Department of Clinical and Experimental Medicine
University of Messina
Policlinico Universitario
Via Consolare Valeria

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Volume: 16 Issue: 7, October 2017

Meet Our Editorial Board Member free to download

Volume:16   Issue: 7
Pp: 739-739
Yukihiro Ohno
DOI: 10.2174/187152731607171009165221
Published on: 09 October, 2017

Recent Advances on the Role of Neurogenesis in the Adult Brain: Therapeutic Potential in Parkinson's and Alzheimer's Diseases

Volume:16   Issue: 7
Pp: 740-748
Khaled Radad*, Rudolf Moldzio, Mubarak Al-Shraim, Barbara Kranner, Christopher Krewenka and Wolf-Dieter Rausch
DOI: 10.2174/1871527316666170623094728
Published on: 22 June, 2017

The Role of Innate Immune System Receptors in Epilepsy Research

Volume:16   Issue: 7
Pp: 749-762
Jessica Cordero-Arreola, Rachel M. West, Julieta Mendoza-Torreblanca, Edna Mendez-Hernandez, Jose Salas-Pacheco, Manuel Menendez-Gonzalez, Rafael C. Freire, Sergio Machado, Eric Murillo-Rodriguez, Antonio E. Nardi and Oscar Arias-Carrion*
DOI: 10.2174/1871527316666170725145549
Published on: 25 July, 2017

Natural Steroids and Androgen Antagonists used as Neuroprotection in Common Neurological Disorders

Volume:16   Issue: 7
Pp: 763-771
David Calderon Guzman, Hugo Juarez Olguin*, Ernestina Hernandez Garcia, Monica Punzo Soto, Mayra Santillan Garcia and Gerardo Barragan Mejia
DOI: 10.2174/1871527316666170714121654
Published on: 14 July, 2017

Increase Signaling of Wnt/β-Catenin Pathway and Presence of Apoptosis in Cerebellum of Kindled Rats

Volume:16   Issue: 7
Pp: 772-780
Carmen Rubio, Artemio Rosiles-Abonce, Cristina Trejo-Solis, Moises Rubio-Osornio, Cesar Mendoza, Veronica Custodio, Juan C Martinez-Lazcano, Edith Gonzalez and Carlos Paz*
DOI: 10.2174/1871527316666170117114513
Published on: 16 January, 2017

Granulocyte Colony-Stimulating Factor Attenuates Blood-Brain Barrier Damage and Improves Cognitive Function in Spontaneously Hypertensive Rats

Volume:16   Issue: 7
Pp: 781-788
Xin Wei, Yan Xu*, Yanling Jin, Hongliang Feng, Yunyue Xiao and Shouquan Dong
DOI: 10.2174/1871527316666170207155730
Published on: 07 February, 2017

Desmoteplase for Acute Ischemic Stroke: A Systematic Review and Metaanalysis of Randomized Controlled Trials

Volume:16   Issue: 7
Pp: 789-799
Ahmed Elmaraezy, Abdelrahman Ibrahim Abushouk, Soha Saad, Moutaz Eltoomy, Osama Mahmoud, Hossam Mahmoud Hassan, Ahmed Aboelmakarem, Ahmed Aboel Fotoh, Farah Althaher, Nguyen Tien Huy* and Kenji Hirayama
DOI: 10.2174/1871527315666161213110104
Published on: 12 December, 2016

Advanced Structure-activity Relationships Applied to Mentha spicata L. Subsp. spicata Essential Oil Compounds as AChE and NMDA Ligands, in Comparison with Donepezil, Galantamine and Memantine – New Approach in Brain Disorders Pharmacology

Volume:16   Issue: 7
Pp: 800-811
Speranta Avram, Maria Mernea*, Eyup Bagci, Lucian Hritcu, Livia-Cristina Borcan and Dan Florin Mihailescu
DOI: 10.2174/1871527316666170113115004
Published on: 12 January, 2017

Lithium Restores Age-related Olfactory Impairment in the Ts65Dn Mouse Model of Down Syndrome

Volume:16   Issue: 7
Pp: 812-819
Sandra Guidi, Patrizia Bianchi, Fiorenza Stagni, Andrea Giacomini, Marco Emili, Stefania Trazzi, Elisabetta Ciani and Renata Bartesaghi*
DOI: 10.2174/1871527315666160801143108
Published on: 01 August, 2016

Inhibition of Butyrylcholinesterase with Fluorobenzylcymserine, An Experimental Alzheimer's Drug Candidate: Validation of Enzoinformatics Results by Classical and Innovative Enzyme Kinetic Analyses

Volume:16   Issue: 7
Pp: 820-827
Mohammad A. Kamal*, Shazi Shakil, Muhammad S. Nawaz, Qian-sheng Yu, David Tweedie, Y. Tan, Xianqin Qu and Nigel H. Greig*
DOI: 10.2174/1871527316666170207160606
Published on: 07 February, 2017

Brain-derived Neurotrophic Factor Promotes Growth of Neurons and Neural Stem Cells Possibly by Triggering the Phosphoinositide 3-Kinase/ AKT/Glycogen Synthase Kinase-3β/β-catenin Pathway

Volume:16   Issue: 7
Pp: 828-836
Xing-tong Li, Zhang Liang, Tong-tong Wang, Jin-wei Yang, Wei Ma, Shi-kang Deng, Xian-bin Wang, Yun-fei Dai, Jian-hui Guo* and Li-yan Li*
DOI: 10.2174/1871527316666170518170422
Published on: 18 May, 2017

The Positive Synergism of CPT and MK-801 in Behavioral Tests and in Reduction of Environmental Stress and Redox Signaling Changes in Mice Cerebral Cortex

Volume:16   Issue: 7
Pp: 837-845
Mariola Herbet*, Aleksandra Szopa, Sylwia Wosko, Anna Serefko, Magdalena Izdebska, Monika Gawronska-Grzywacz, Iwona Piatkowska-Chmiel, Martyna Janas, Renata Gieroba, Agnieszka Korga, Ewa Poleszak and Jaroslaw Dudka
DOI: 10.2174/1871527315666161010152414
Published on: 10 October, 2016

Differential Mechanisms Underlying Antidepressant Responses of Ketamine and Imipramine

Volume:16   Issue: 7
Pp: 846-853
Zhisheng Wei, Ke Zhang, Qinji Zhou, Mingfa Huang, Ting Xu, Jianyang Dong, Yu Zheng and Xiang Cai*
DOI: 10.2174/1871527316666170428123248
Published on: 28 April, 2017