CNS & Neurological Disorders - Drug Targets

Formerly Current Drug Targets - CNS & Neurological Disorders


Edoardo Spina
Department of Clinical and Experimental Medicine
University of Messina
Policlinico Universitario
Via Consolare Valeria

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Volume: 13 Issue: 8, October 2014

Commentary: Research Highlights: IKKβ Mediates Aβ-Triggered Microglial Inflammation and Neuronal Death During Alzheimer's Disease

Volume:13   Issue: 8
Pp: 1305-1307
S.M. Fayaz and G.K. Rajanikant
DOI: 10.2174/1871527313666141112161847
Published on: 12 November, 2014

Conference Report: 12th International Congress on Neuroprotective Agents (ICNA), Charlottesville, VA, USA September 28, 2014-Ocobert 01, 2014

Volume:13   Issue: 8
Pp: 1308-1309
Hari S. Sharma, Stephen D. Skaper and Aruna Sharma
DOI: 10.2174/1871527313666141112163159
Published on: 12 November, 2014

Editorial (Thematic Issue: Linkage of Neurodegenerative Disorders with Other Health Issues – Volume II) free to download

Volume:13   Issue: 8
Pp: 1310-1314
Mohammad Amjad Kamal
DOI: 10.2174/1871527313666141112162703
Published on: 12 November, 2014

Role of Nanomedicines in Delivery of Anti-Acetylcholinesterase Compounds to the Brain in Alzheimer’s Disease

Volume:13   Issue: 8
Pp: 1315-1324
Mohammad Z. Ahmad, Javed Ahmad, Saima Amin, Mahfoozur Rahman, Mohammad Anwar, Neha Mallick, Farhan J. Ahmad, Ziyaur Rahman, Mohammad A. Kamal and Sohail Akhter
DOI: 10.2174/1871527313666141023100618
Published on: 22 October, 2014

Implication of Gut Microbiota in Human Health

Volume:13   Issue: 8
Pp: 1325-1333
Imran Khan, Muhammad Yasir, Esam I. Azhar, Taha Kumosani, Elie K. Barbour, Fehmida Bibi and Mohammad A. Kamal
DOI: 10.2174/1871527313666141023153506
Published on: 23 October, 2014

Gene Expression Analysis Approach to Establish Possible Links Between Parkinson's Disease, Cancer and Cardiovascular Diseases

Volume:13   Issue: 8
Pp: 1334-1345
Sajjad Karim, Zeenat Mirza, Mohammad A. Kamal, Adel M. Abuzenadah and Mohammed H. Al-Qahtani
DOI: 10.2174/1871527313666141023122803
Published on: 23 October, 2014

Identification of Potent Caspase-3 Inhibitors for Treatment of Multi- Neurodegenerative Diseases Using Pharmacophore Modeling and Docking Approaches

Volume:13   Issue: 8
Pp: 1346-1353
Khurshid Ahmad, Vishal M. Balaramnavar, Mohammad H. Baig, Ashwini K. Srivastava, Saif Khan and Mohammad A. Kamal
DOI: 10.2174/1871527313666141023120843
Published on: 23 October, 2014

The Implications of Sortilin/Vps10p Domain Receptors in Neurological and Human Diseases

Volume:13   Issue: 8
Pp: 1354-1365
Cornelia M. Wilson, Thomas Naves, Sofiane Saada, Sandra Pinet, Francois Vincent, Fabrice Lalloue and Marie-Odile Jauberteau
DOI: 10.2174/1871527313666141023151642
Published on: 23 October, 2014

Molecular Dynamics and Regulation of Butyrylcholinesterase Cholinergic Activity by RNA Binding Proteins

Volume:13   Issue: 8
Pp: 1366-1377
Iqra Sohail and Sajid Rashid
DOI: 10.2174/1871527313666141023144523
Published on: 23 October, 2014

Inflammation in Ischemic Stroke: Mechanisms, Consequences and Possible Drug Targets

Volume:13   Issue: 8
Pp: 1378-1396
Muzamil Ahmad, Nawab J. Dar, Zubair S. Bhat, Aehtesham Hussain, Ayatullah Shah, Hao Liu and Steven H. Graham
DOI: 10.2174/1871527313666141023094720
Published on: 22 October, 2014

Sub-Chronic Exposure of Non-Observable Adverse Effect Dose of Terbufos Sulfone: Neuroinflammation in Diabetic and Non-Diabetic Rats

Volume:13   Issue: 8
Pp: 1397-1405
Syed M. Nurulain, Ernest Adeghate, Azimullah Sheikh, Javed Yasin, Mohammad A. Kamal, Charu Sharma, Abdu Adem and Shreesh Ojha
DOI: 10.2174/1871527313666141023142539
Published on: 23 October, 2014

Effect of Electromagnetic Radiations on Neurodegenerative Diseases- Technological Revolution as a Curse in Disguise

Volume:13   Issue: 8
Pp: 1406-1412
Gulam M. Hasan, Ishfaq A. Sheikh, Sajjad Karim, Absarul Haque, Mohammad A. Kamal, Adeel G. Chaudhary, Essam Azhar and Zeenat Mirza
DOI: 10.2174/1871527313666141023122340
Published on: 23 October, 2014

Down Regulated Expression of Claudin-1 and Claudin-5 and Up Regulation of β-Catenin: Association with Human Glioma Progression

Volume:13   Issue: 8
Pp: 1413-1426
Hanuma K. Karnati, Manas Panigrahi, Noor A. Shaik, Nigel H. Greig, S. Appala R. Bagadi, Mohammad A. Kamal and Nagaiah Kapalavayi
DOI: 10.2174/1871527313666141023121550
Published on: 23 October, 2014

Fetzima (levomilnacipran), a Drug for Major Depressive Disorder as a Dual Inhibitor for Human Serotonin Transporters and Beta-Site Amyloid Precursor Protein Cleaving Enzyme-1

Volume:13   Issue: 8
Pp: 1427-1431
Syed Mohd. Danish Rizvi, Sibhghatulla Shaikh, Mahiuddin Khan, Deboshree Biswas, Nida Hameed and Shazi Shakil
DOI: 10.2174/1871527313666141023145703
Published on: 23 October, 2014

Status of Acetylcholinesterase and Butyrylcholinesterase in Alzheimer's Disease and Type 2 Diabetes Mellitus

Volume:13   Issue: 8
Pp: 1432-1439
Gohar Mushtaq, Nigel H. Greig, Jalaluddin A. Khan and Mohammad A. Kamal
DOI: 10.2174/1871527313666141023141545
Published on: 23 October, 2014

Current Challenges to Overcome in the Management of Type 2 Diabetes Mellitus and Associated Neurological Disorders

Volume:13   Issue: 8
Pp: 1440-1457
Nazir M. Khan, Ausaf Ahmad, Rajesh K. Tiwari, Mohammad A. Kamal, Gohar Mushtaq and Ghulam M. Ashraf
DOI: 10.2174/1871527313666141023160448
Published on: 23 October, 2014

Flavonoids Isolated from Rumex aquaticus Exhibit Neuroprotective and Neurorestorative Properties by Enhancing Neurite Outgrowth and Synaptophysin

Volume:13   Issue: 8
Pp: 1458-1464
Orsolya Orban-Gyapai, Aparna Raghavan, Andrea Vasas, Peter Forgo, Judit Hohmann and Zahoor A. Shah
DOI: 10.2174/1871527313666141023154446
Published on: 23 October, 2014

The Neuroprotective Mechanism of Erythropoietin-TAT Fusion Protein Against Neurodegeneration from Ischemic Brain Injury

Volume:13   Issue: 8
Pp: 1465-1474
Ping Liu, Xiaolei Liu, Anthony Kian-Fong Liou, Juan Xing, Zheng Jing, Xunming Ji, Xiangrong Liu, Haiping Zhao, Feng Yan, Jun Chen, Guodong Cao and Yumin Luo
DOI: 10.2174/1871527313666140806155259
Published on: 06 August, 2014

Poly (D,L-Lactide-co-Glycolide) Nanoparticles Loaded with Cerebrolysin Display Neuroprotective Activity in a Rat Model of Concussive Head Injury

Volume:13   Issue: 8
Pp: 1475-1482
Barbara Ruozi, Daniela Belletti, Flavio Forni, Aruna Sharma, Dafin Muresanu, Herbert Mossler, Maria A. Vandelli, Giovanni Tosi and Hari S. Sharma
DOI: 10.2174/1871527313666140806145540
Published on: 06 August, 2014