CNS & Neurological Disorders - Drug Targets

Formerly Current Drug Targets - CNS & Neurological Disorders

Editor-in-Chief

Edoardo Spina
Department of Clinical and Experimental Medicine
University of Messina
Policlinico Universitario
Via Consolare Valeria
Messina
(Italy)

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Volume: 13 Issue: 7, September 2014



Conference Report: 9th International Summer School of Neurology

Volume:13   Issue: 7
Pp: 1121-1124
Stephen D. Skaper
DOI: 10.2174/187152731307141015103424
Published on: 14 October, 2014



Editorial (Thematic Issue: Linkage of Neurodegenerative Disorders with Other Health Issues – Volume I) free to download

Volume:13   Issue: 7
Pp: 1125-1129
Mohammad Amjad Kamal
DOI: 10.2174/1871527313666141002130423
Published on: 02 October, 2014

Quinoline Derivatives: Candidate Drugs for a Class B G-Protein Coupled Receptor, the Calcitonin Gene-Related Peptide Receptor, a Cause of Migraines

Volume:13   Issue: 7
Pp: 1130-1139
Hira Iftikhar, Iqra Ahmad, Siew H. Gan, Munvar M. Shaik, Naveed Iftikhar, Muhammad S. Nawaz, Nigel H. Greig and Mohammad A. Kamal
DOI: 10.2174/1871527313666140917111341
Published on: 17 September, 2014

Link Between Chronic Bacterial Inflammation and Alzheimer Disease

Volume:13   Issue: 7
Pp: 1140-1147
Fehmida Bibi, Muhammad Yasir, Sayed S. Sohrab, Esam I. Azhar, Mohammed H. Al-Qahtani, Adel M. Abuzenadah, Mohammad A. Kamal and Muhammad I. Naseer
DOI: 10.2174/1871527313666140917115741
Published on: 17 September, 2014

Interaction of Different Proteins with GABAA Receptor and their Modulatory Effect on Inhibitory Neural Transmission Leads to Epilepsy

Volume:13   Issue: 7
Pp: 1148-1159
Muhammad Faheem, Adeel G. Chaudhary, Taha A. Kumosani, Mohammad H. Al-Qahtani, Muhammad Yasir, Fehmida Bibi, Myeong O. Kim, Mahmood Rasool and Muhammad I. Naseer
DOI: 10.2174/1871527313666140917115121
Published on: 17 September, 2014

The Impact of Dementia Development Concurrent with Parkinson's Disease: A New Perspective

Volume:13   Issue: 7
Pp: 1160-1168
Alyce Russell, Alesya Drozdova, Wei Wang and Meghan Thomas
DOI: 10.2174/1871527313666140917122739
Published on: 17 September, 2014

Computational Study of Human Tyrosine Hydroxylase Mutants to Uphold [4-(Propan-2-yl) Phenyl]Carbamic Acid as a Potential Inhibitor

Volume:13   Issue: 7
Pp: 1169-1174
Muhammad S. Nawaz, Zahida Parveen, Liyong Wang, Sajid Rashid, Muhammad Q. Fatmi and Mohammad A. Kamal
DOI: 10.2174/1871527313666140917111905
Published on: 17 September, 2014

Natural Compounds and Plant Extracts as Therapeutics Against Chronic Inflammation in Alzheimer's Disease - A Translational Perspective

Volume:13   Issue: 7
Pp: 1175-1191
Nadine Apetz, Gerald Munch, Suresh Govindaraghavan and Erika Gyengesi
DOI: 10.2174/1871527313666140917110635
Published on: 17 September, 2014

Biological Mechanisms Linking Alzheimer's Disease and Type-2 Diabetes Mellitus

Volume:13   Issue: 7
Pp: 1192-1201
Gohar Mushtaq, Jalaluddin A. Khan and Mohammad A. Kamal
DOI: 10.2174/1871527313666140917114537
Published on: 17 September, 2014

Transcriptomics Study of Neurodegenerative Disease: Emphasis on Synaptic Dysfunction Mechanism in Alzheimer's Disease

Volume:13   Issue: 7
Pp: 1202-1212
Sajjad Karim, Zeenat Mirza, Shakeel A. Ansari, Mahmood Rasool, Zafar Iqbal, Sayed S. Sohrab, Mohammad A. Kamal, Adel M. Abuzenadah and Mohammed H. Al-Qahtani
DOI: 10.2174/1871527313666140917113446
Published on: 17 September, 2014

The Role of Viruses in Neurodegenerative and Neurobehavioral Diseases

Volume:13   Issue: 7
Pp: 1213-1223
Sajjad Karim, Zeenat Mirza, Mohammad A. Kamal, Adel M.Abuzenadah, Esam I. Azhar, Mohammed H. Al-Qahtani, Ghazi A. Damanhouri, Fahim Ahmad, Siew H. Gan and Sayed S. Sohrab
DOI: 10.2174/187152731307141015122638
Published on: 15 October, 2014

Protein Interactions Between the C-Terminus of Aβ-Peptide and Phospholipase A2 - A Structure Biology Based Approach to Identify Novel Alzheimer's Therapeutics

Volume:13   Issue: 7
Pp: 1224-1231
Zeenat Mirza, Vikram G. Pillai and Mohammad A. Kamal
DOI: 10.2174/1871527313666140917112248
Published on: 17 September, 2014

Regulatory Cascade of Neuronal Loss and Glucose Metabolism

Volume:13   Issue: 7
Pp: 1232-1245
Mubashir Hassan, Sheikh A. Sehgal and Sajid Rashid
DOI: 10.2174/1871527313666140917120444
Published on: 17 September, 2014

Ignored Avenues in Alpha-Synuclein Associated Proteopathy

Volume:13   Issue: 7
Pp: 1246-1257
Rimpy K. Chowhan, Shruti Mittal, Tanveer A. Dar, Mohammad A. Kamal and Laishram R. Singh
DOI: 10.2174/1871527313666140917121943
Published on: 17 September, 2014

Aptiom (Eslicarbazepine Acetate) as a Dual Inhibitor of β-Secretase and Voltage-Gated Sodium Channel: Advancement in Alzheimer's Disease-Epilepsy Linkage via an Enzoinformatics Study

Volume:13   Issue: 7
Pp: 1258-1262
Sibhghatulla Shaikh, Syed M.D. Rizvi, Nida Hameed, Deboshree Biswas, Mahiuddin Khan, Shazi Shakil and Mohammad A. Kamal
DOI: 10.2174/1871527313666140917121600
Published on: 17 September, 2014

Expression and Secretion of Wild Type and Mutant GNE Proteins in Dictyostelium discoideum

Volume:13   Issue: 7
Pp: 1263-1272
Sonam Grover, Saima Aslam, Vijeta Sharma and Ranjana Arya
DOI: 10.2174/1871527313666140917094905
Published on: 16 September, 2014

New Targets for Treating the Underlying Pathophysiology and Nonmotor Aspects of Parkinson's Disease

Volume:13   Issue: 7
Pp: 1273-1279
Jonathan T. Butler and Christopher Tolleson
DOI: 10.2174/1871527313666140917104850
Published on: 16 September, 2014

Protein Misfolding and Aggregation in Alzheimer's Disease and Type 2 Diabetes Mellitus

Volume:13   Issue: 7
Pp: 1280-1293
Ghulam M. Ashraf, Nigel H. Greig, Taqi A. Khan, Iftekhar Hassan, Shams Tabrez, Shazi Shakil, Ishfaq A. Sheikh, Syed K. Zaidi, Mohammad Akram, Nasimudeen R. Jabir, Chelaprom K. Firoz, Aabgeena Naeem, Ibrahim M. Alhazza, Ghazi A. Damanhouri and Mohammad A. Kamal
DOI: 10.2174/1871527313666140917095514
Published on: 16 September, 2014

Cholinergic System Dysfunction and Neurodegenerative Diseases: Cause or Effect?

Volume:13   Issue: 7
Pp: 1294-1303
Ada M. Tata, Lucia Velluto, Chiara D'Angelo and Marcella Reale
DOI: 10.2174/1871527313666140917121132
Published on: 17 September, 2014