CNS & Neurological Disorders - Drug Targets

Formerly Current Drug Targets - CNS & Neurological Disorders


Edoardo Spina
Department of Clinical and Experimental Medicine
University of Messina
Policlinico Universitario
Via Consolare Valeria

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Volume: 13 Issue: 4, June 2014

Conference Report: The American Association for the Advancement of Science (AAAS), 180th Annual Meeting Chicago, IL, USA Feb 13-17, 2014 “Meeting Global Challenges: Discoveries & Innovation”

Volume:13   Issue: 4
Pp: 553-555
Hari S. Sharma and Aruna Sharma
DOI: 10.2174/187152731304140702104643
Published on: 01 July, 2014

Commentary (Research Highlights: Wnt-Signalling: A New Direction for Alzheimer Disease?)

Volume:13   Issue: 4
Pp: 556-556
Stephen D. Skaper
DOI: 10.2174/187152731304140702104826
Published on: 01 July, 2014

Editorial (Thematic Issue: Molecular Targeting for Development of Novel Therapeutic Strategies in Brain Diseases: Myth or Reality?) free to download

Volume:13   Issue: 4
Pp: 557-557
Jean F. Soustiel
DOI: 10.2174/18715273113126660201
Published on: 28 October, 2013

Positive Allosteric Modulators (PAMs) of Metabotropic Glutamate Receptor 5 (mGluR5) Attenuate Microglial Activation

Volume:13   Issue: 4
Pp: 558-566
Fengtian Xue, Bogdan A. Stoica, Marie Hanscom, Shruti V. Kabadi and Alan I. Faden
DOI: 10.2174/18715273113126660199
Published on: 28 October, 2013

Novel Approach to the Role of NMDA Receptors in Traumatic Brain Injury

Volume:13   Issue: 4
Pp: 567-573
Esther Shohami and Anat Biegon
DOI: 10.2174/18715273113126660196
Published on: 28 October, 2013

Subcellular Injuries in Alzheimer's Disease

Volume:13   Issue: 4
Pp: 593-605
Jean-Paul Tillement and Vassilios Papadopoulos
DOI: 10.2174/18715273113126660197
Published on: 28 October, 2013

Mitochondrial Neuroprotection in Traumatic Brain Injury: Rationale and Therapeutic Strategies

Volume:13   Issue: 4
Pp: 606-619
Shoji Yokobori, Anna T. Mazzeo, Shyam Gajavelli and Malcolm R. Bullock
DOI: 10.2174/187152731304140702112805
Published on: 02 July, 2014

Involvement of the Mitochondrial Benzodiazepine Receptor in Traumatic Brain Injury: Therapeutic Implications

Volume:13   Issue: 4
Pp: 620-629
Eugene Vlodavsky, Eilam Palzur and Jean F. Soustiel
DOI: 10.2174/187152731304140702114630
Published on: 02 July, 2014

α-Synuclein Ubiquitination and Novel Therapeutic Targets for Parkinson's Disease

Volume:13   Issue: 4
Pp: 630-637
Ruth Rott, Raymonde Szargel, Vered Shani, Sleman Bisharat and Simone Engelender
DOI: 10.2174/18715273113126660195
Published on: 28 October, 2013

Citrus Peel Extract Attenuates Acute Cyanide Poisoning-Induced Seizures and Oxidative Stress in Rats

Volume:13   Issue: 4
Pp: 638-646
Ahmed E. Abdel Moneim
DOI: 10.2174/1871527312666131206095142
Published on: 05 December, 2013

Effect of Glatiramer Acetate on Peripheral Blood Brain-Derived Neurotrophic Factor and Phosphorylated TrkB Levels in Relapsing- Remitting Multiple Sclerosis

Volume:13   Issue: 4
Pp: 647-651
Vitalie Vacaras, Zsigmond Z. Major, Dafin F. Muresanu, Tibor L. Krausz, Ioan Marginean and Dana A. Buzoianu
DOI: 10.2174/1871527313666140618110049
Published on: 18 June, 2014

Significant Overlapping Modules and Biological Processes Between Stroke and Coronary Heart Disease

Volume:13   Issue: 4
Pp: 652-660
Yingying Zhang, Pengyun Kong, Yinying Chen, Yanan Yu, Jun Liu, Liqiang Yang, Tao Zhao, Jingyi Nan and Zhong Wang
DOI: 10.2174/1871527312666131223115112
Published on: 22 December, 2013

Effects of Brain IKKβ Gene Silencing by Small Interfering RNA on P-Glycoprotein Expression and Brain Damage in the Rat Kainic Acid-Induced Seizure Model

Volume:13   Issue: 4
Pp: 661-672
Nian Yu, Hao Liu, Yan-Fang Zhang, Ling-Ying Su, Xin-Hong Liu, Le-Chao Li, Jin-Bo Hao, Xian-Jing Huang and Qing Di
DOI: 10.2174/18715273113129990106
Published on: 27 August, 2013

Scopolamine and Depression: A Role for Muscarinic Antagonism?

Volume:13   Issue: 4
Pp: 673-683
Helge Hasselmann
DOI: 10.2174/1871527313666140618105710
Published on: 17 June, 2014

Neuroprotective Effects of Citrus reticulata in Scopolamine-Induced Dementia Oxidative Stress in Rats

Volume:13   Issue: 4
Pp: 684-690
Manal F. El-Khadragy, Ebtesam M. Al-Olayan and Ahmed E. Abdel Moneim
DOI: 10.2174/1871527313666140618105404
Published on: 17 June, 2014

Crystal Structure and Interaction of Phycocyanin with β-Secretase: A Putative Therapy for Alzheimer's Disease

Volume:13   Issue: 4
Pp: 691-698
Niraj Kumar Singh, Syed S. Hasan, Jitendra Kumar, Isha Raj, Amrin A. Pathan, Asha Parmar, Shazi Shakil, Samudrala Gourinath and Datta Madamwar
DOI: 10.2174/1871527313666140228114456
Published on: 27 February, 2014

Computational Analysis of TRAPPC9: Candidate Gene for Autosomal Recessive Non-Syndromic Mental Retardation

Volume:13   Issue: 4
Pp: 699-711
Naureen Aslam Khattak and Asif Mir
DOI: 10.2174/18715273113129990105
Published on: 27 August, 2013

Cerebrovascular Profile Assessment in Parkinson's Disease Patients

Volume:13   Issue: 4
Pp: 712-717
Laura Perju-Dumbrava, Maria-Lucia Muntean and Dafin Fior Muresanu
DOI: 10.2174/1871527313666140618110409
Published on: 18 June, 2014