CNS & Neurological Disorders - Drug Targets

Formerly Current Drug Targets - CNS & Neurological Disorders

Editor-in-Chief

Edoardo Spina
Department of Clinical and Experimental Medicine
University of Messina
Policlinico Universitario
Via Consolare Valeria
Messina
(Italy)

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Volume: 13 Issue: 10, December 2015



Commentary-1 (Research Highlights: USP30 Regulates the Mitophagy-Mediated Neuroprotection in Parkinson’s Disease)

Volume:13   Issue: 10
Pp: 1633-1634
Rajanikant G. Krishnmurthy and Fayaz M. Shradgan
DOI: 10.2174/1871527314666141226122809
Published on: 26 December, 2014



Commentary-2: Repairing the Dopamine System in the Brain with Adult Neurogenesis

Volume:13   Issue: 10
Pp: 1635-1636
Ti-Fei Yuan and Oscar Arias-Carrion
DOI: 10.2174/1871527314666141226122933
Published on: 26 December, 2014



Editorial (Thematic Issue: Cognitive Dysfunction in Major Depressive Disorder - Pathophysiology, Clinical Implications and Treatment Opportunities) free to download

Volume:13   Issue: 10
Pp: 1637-1639
Andre F. Carvalho, Konstantinos N. Fountoulakis and Roger S. McIntyre
DOI: 10.2174/1871527314666141226122612
Published on: 26 December, 2014

Effects of Physical Exercise on Depressive Symptoms and Biomarkers in Depression

Volume:13   Issue: 10
Pp: 1640-1653
Trevor Archer, Torbjorn Josefsson and Magnus Lindwall
DOI: 10.2174/1871527313666141130203245
Published on: 30 November, 2014

Neuroinflammation, Microglia and Mast Cells in the Pathophysiology of Neurocognitive Disorders: A Review

Volume:13   Issue: 10
Pp: 1654-1666
Stephen D. Skaper, Laura Facci and Pietro Giusti
DOI: 10.2174/1871527313666141130224206
Published on: 30 November, 2014

Are Major Depressive Disorder and Diabetes Mellitus Amyloidogenic Conditions?

Volume:13   Issue: 10
Pp: 1667-1676
Anusha Baskaran, Andre F. Carvalho, Rodrigo B. Mansur and Roger S. McIntyre
DOI: 10.2174/1871527313666141130204300
Published on: 30 November, 2014

Psychological Treatments for Cognitive Dysfunction in Major Depressive Disorder: Current Evidence and Perspectives§

Volume:13   Issue: 10
Pp: 1677-1692
Richard J. Porter, Katie Douglas, Jennifer Jordan, Christopher R. Bowie, Jonathan Roiser and Gin S. Malhi
DOI: 10.2174/1871527313666141130223248
Published on: 30 November, 2014

Towards a “Metabolic” Subtype of Major Depressive Disorder: Shared Pathophysiological Mechanisms May Contribute to Cognitive Dysfunction

Volume:13   Issue: 10
Pp: 1693-1707
Celina S. Liu, Andre F. Carvalho and Roger S. McIntyre
DOI: 10.2174/1871527313666141130204031
Published on: 30 November, 2014

Hippocampal Neurogenesis, Neurotrophic Factors and Depression: Possible Therapeutic Targets?

Volume:13   Issue: 10
Pp: 1708-1721
Gianluca Serafini, Shawn Hayley, Maurizio Pompili, Yogesh Dwivedi, Goutam Brahmachari, Paolo Girardi and Mario Amore
DOI: 10.2174/1871527313666141130223723
Published on: 30 November, 2014

The Neuropsychological Hypothesis of Antidepressant Drug Action Revisited

Volume:13   Issue: 10
Pp: 1722-1739
Niki Antypa, Raffaella Calati and Alessandro Serretti
DOI: 10.2174/1871527313666141130224004
Published on: 30 November, 2014

Major Depressive Disorder and Type II Diabetes Mellitus: Mechanisms Underlying Risk for Alzheimer’s Disease

Volume:13   Issue: 10
Pp: 1740-1749
Danielle S. Cha, Andre F. Carvalho, Joshua D. Rosenblat, Muna M. Ali and Roger S. McIntyre
DOI: 10.2174/1871527313666141130204535
Published on: 30 November, 2014

The Putative Impact of Metabolic Health on Default Mode Network Activity and Functional Connectivity in Neuropsychiatric Disorders

Volume:13   Issue: 10
Pp: 1750-1758
Danielle S. Cha, Francesco De Michele, Joanna K. Soczynska, Hanna O. Woldeyohannes, Oksana Kaidanovich-Beilin, Andre F. Carvalho, Gin S. Malhi, Hiren Patel, Kang Sim, Elisa Brietzke, Rodrigo Mansur, Katharine A.M. Dunlop, Mohammad Alsuwaidan, Anusha Baskaran, Andrea Fagiolini, Roman Reznikov, Paul A. Kudlow and Roger S. McIntyre
DOI: 10.2174/1871527313666141130205024
Published on: 30 November, 2014

Does Non-Invasive Brain Stimulation Improve Cognition in Major Depressive Disorder? A Systematic Review

Volume:13   Issue: 10
Pp: 1759-1769
Gabriel Tortella, Priscila M.L. Selingardi, Marina L. Moreno, Beatriz P. Veronezi and Andre R. Brunoni
DOI: 10.2174/1871527313666141130224431
Published on: 30 November, 2014

Gut Emotions - Mechanisms of Action of Probiotics as Novel Therapeutic Targets for Depression and Anxiety Disorders

Volume:13   Issue: 10
Pp: 1770-1786
Anastasiya Slyepchenko, Andre F. Carvalho, Danielle S. Cha, Siegfried Kasper and Roger S. McIntyre
DOI: 10.2174/1871527313666141130205242
Published on: 30 November, 2014

‘Hot’ Cognition in Major Depressive Disorder: A Systematic Review

Volume:13   Issue: 10
Pp: 1787-1803
Kamilla W. Miskowiak and Andre F. Carvalho
DOI: 10.2174/1871527313666141130205713
Published on: 30 November, 2014

Cognitive Dysfunction in Major Depressive Disorder: A State-of-the-Art Clinical Review

Volume:13   Issue: 10
Pp: 1804-1818
Beatrice Bortolato, Andre F. Carvalho and Roger S. McIntyre
DOI: 10.2174/1871527313666141130203823
Published on: 30 November, 2014

Cognitive Dysfunction in Depression – Pathophysiology and Novel Targets

Volume:13   Issue: 10
Pp: 1819-1835
Andre F. Carvalho, Kamilla K. Miskowiak, Thomas N. Hyphantis, Cristiano A. Kohler, Gilberto S. Alves, Beatrice Bortolato, Paulo Marcelo G. Sales, Rodrigo Machado-Vieira, Michael Berk and Roger S. McIntyre
DOI: 10.2174/1871527313666141130203627
Published on: 30 November, 2014

Metformin: Repurposing Opportunities for Cognitive and Mood Dysfunction

Volume:13   Issue: 10
Pp: 1836-1845
Melissa A. Ying, Nadia Maruschak, Rodrigo Mansur, Andre F. Carvalho, Danielle S. Cha and Roger S. McIntyre
DOI: 10.2174/1871527313666141130205514
Published on: 30 November, 2014

Structural Neuroimaging Findings in Major Depressive Disorder Throughout Aging: A Critical Systematic Review of Prospective Studies

Volume:13   Issue: 10
Pp: 1846-1859
Gilberto S. Alves, Andre F. Carvalho, Felipe K. Sudo, Viola Oertel-Knochel, Christian Knochel, Luiza de Amorim de Carvalho, Jerson Laks, Eliasz Engelhardt and Johannes Pantel
DOI: 10.2174/1871527313666141130202923
Published on: 30 November, 2014

Cognitive Dysfunction in Depression: Lessons Learned from Animal Models

Volume:13   Issue: 10
Pp: 1860-1870
Gislaine Z. Reus, Helena M. Abelaira, Daniela D. Leffa and Joao Quevedo
DOI: 10.2174/1871527313666141130223453
Published on: 30 November, 2014

Acknowledgements to the Reviewers:

Volume:13   Issue: 10
Pp: 1871-1871

DOI: 10.2174/187152731310150122231358
Published on: 22 January, 2015