CNS & Neurological Disorders - Drug Targets

Formerly Current Drug Targets - CNS & Neurological Disorders


Edoardo Spina
Department of Clinical and Experimental Medicine
University of Messina
Policlinico Universitario
Via Consolare Valeria

Personal Subscription
Become EABM
Become Reviewer
Call for Editor
Volume: 12 Issue: 8, December 2014

Commentary: Olfactory Dysfunction in Parkinson’s Disease

Volume:12   Issue: 8
Pp: 1079-1080
Jiang Li, Ying Cui, Ti-Fei Yuan and Oscar Arias-Carrion
DOI: 10.2174/1871527312999131230144317
Published on: 30 December, 2013

Commentary: Multifactoriality of Amytrophic Lateral Sclerosis: Linking Unfolded Proteins to Oxidative Stress in Microglia

Volume:12   Issue: 8
Pp: 1081-1082
Nadia D’Ambrosi and Cinzia Volonte
DOI: 10.2174/18715273113129990113
Published on: 03 September, 2013

Editorial (Thematic Issue: Novel Perspectives for Parkinson’s Disease Therapy: Insights from the Latest Advances in Disease Pathophysiology, Diagnostic and Experimental Tools and Molecular Targets)

Volume:12   Issue: 8
Pp: 1083-1085
Pier Franco Spano and Arianna Bellucci
DOI: 10.2174/187152731131200129
Published on: 06 September, 2013

Overlapping Molecular Signatures in Parkinson's Patient Leukocytes Before and After Treatment and in Mouse Model Brain Regions

Volume:12   Issue: 8
Pp: 1086-1093
Lilach Soreq, Hagai Bergman, Zvi Israel and Hermona Soreq
DOI: 10.2174/187152731131200119
Published on: 04 September, 2013

Synaptic Dysfunction in Synucleinopathies

Volume:12   Issue: 8
Pp: 1094-1100
Oleg Anichtchik, Laura Calo and Maria Grazia Spillantini
DOI: 10.2174/18715273113129990114
Published on: 03 September, 2013

Receptor Heteromers in Parkinson’s Disease and L-DOPA-Induced Dyskinesia

Volume:12   Issue: 8
Pp: 1101-1113
Chiara Fiorentini, Paola Savoia, Daria Savoldi and Cristina Missale
DOI: 10.2174/187152731131200118
Published on: 04 September, 2013

Induced Pluripotent Stem Cell-Based Studies of Parkinson's Disease: Challenges and Promises

Volume:12   Issue: 8
Pp: 1114-1127
Adriana Sanchez-Danes, Patrizia Benzoni, Maurizio Memo, Patrizia Dell’Era, Angel Raya and Antonella Consiglio
DOI: 10.2174/187152731131200128
Published on: 06 September, 2013

Targeting Striatal Metabotropic Glutamate Receptor Type 5 in Parkinson’s Disease: Bridging Molecular Studies and Clinical Trials

Volume:12   Issue: 8
Pp: 1128-1142
A. Vallano, V. Fernandez-Duenas, G. Garcia-Negredo, M.A. Quijada, C.P. Simon, M.L. Cuffí, L. Carbonell, S. Sanchez, J.M. Arnau and F. Ciruela
DOI: 10.2174/18715273113129990115
Published on: 03 September, 2013

Editorial: Steroid-Dependent Management of Biological Responses in the Nervous System free to download

Volume:12   Issue: 8
Pp: 1143-1145
Mario D. Galigniana
DOI: 10.2174/187152731131200127
Published on: 04 September, 2013

Pathogenic Mechanisms and Therapeutic Strategies in Spinobulbar Muscular Atrophy

Volume:12   Issue: 8
Pp: 1146-1156
Jason P. Chua and Andrew P. Lieberman
DOI: 10.2174/187152731131200124
Published on: 04 September, 2013

The Role of FKBP5 in Mood Disorders: Action of FKBP5 on Steroid Hormone Receptors Leads to Questions About its Evolutionary Importance

Volume:12   Issue: 8
Pp: 1157-1162
John C. O’Leary III, Bo Zhang, John Koren III, Laura Blair and Chad A. Dickey
DOI: 10.2174/187152731131200121
Published on: 04 September, 2013

Molecular Basis of Mineralocorticoid Receptor Action in the Nervous System

Volume:12   Issue: 8
Pp: 1163-1174
Alejandro M. Molinari, Mayra Y. Machado-Rada, Gisela I. Mazaira, Alejandra G. Erlejman and Mario D. Galigniana
DOI: 10.2174/187152731131200122
Published on: 04 September, 2013

Contribution of Glucocorticoids and Glucocorticoid Receptors to the Regulation of Neurodegenerative Processes open access plus

Volume:12   Issue: 8
Pp: 1175-1193
Sheela Vyas and Layal Maatouk
DOI: 10.2174/187152731131200125
Published on: 04 September, 2013

Comparison of Glucocorticoid Receptor- and Epigenetically Regulated Genes in Proliferating Versus Growth-Arrested Neuro-2a Cells

Volume:12   Issue: 8
Pp: 1194-1204
Jurgen Zschocke, Peter Weber, Nicole Zimmermann and Theo Rein
DOI: 10.2174/187152731131200126
Published on: 04 September, 2013

Therapeutic Effects of Progesterone in Animal Models of Neurological Disorders

Volume:12   Issue: 8
Pp: 1205-1218
Alejandro F. De Nicola, Florencia Coronel, Laura I. Garay, Gisella Gargiulo-Monachelli, Maria Claudia Gonzalez Deniselle, Susana L. Gonzalez, Florencia Labombarda, Maria Meyer, Rachida Guennoun and Michael Schumacher
DOI: 10.2174/187152731131200120
Published on: 04 September, 2013

Neuroprotective Effects of Non-Classical Estrogen-Like Signaling Activators: from Mechanism to Potential Implications

Volume:12   Issue: 8
Pp: 1219-1225
Andrea Kwakowsky, Zsombor Koszegi, Rachel Y. Cheong and Istvan M. Abraham
DOI: 10.2174/187152731131200123
Published on: 04 September, 2013

Chronic Paroxetine Treatment: Effects on Other Non-Serotonergic Neurotransmitter Systems

Volume:12   Issue: 8
Pp: 1226-1232
Paola Ballesteros-Zebadua, Joaquin Manjarrez-Marmolejo and Javier Franco-Perez
DOI: 10.2174/18715273113126660182
Published on: 13 October, 2013

Serum Cytokine Profile in Alzheimer's Disease Patients After Ingestion of an Antioxidant Beverage

Volume:12   Issue: 8
Pp: 1233-1241
J.M. Rubio-Perez and J.M. Morillas-Ruiz
DOI: 10.2174/18715273113129990075
Published on: 05 July, 2013

Exploring the Role of Nerve Growth Factor in Multiple Sclerosis: Implications in Myelin Repair open access plus

Volume:12   Issue: 8
Pp: 1242-1256
C.M.R. Acosta, C. Cortes, H. MacPhee and M.P. Namaka
DOI: 10.2174/18715273113129990087
Published on: 09 July, 2013

Beyond Rodent Models of Pain: Non-Human Primate Models for Evaluating Novel Analgesic Therapeutics and Elaborating Pain Mechanisms

Volume:12   Issue: 8
Pp: 1257-1270
Aldric T. Hama, Katsuo Toide and Hiroyuki Takamatsu
DOI: 10.2174/18715273113129990111
Published on: 27 August, 2013

Highly Organized Nanostructures for Brain Drug Delivery - New Hope or Just a Fad?

Volume:12   Issue: 8
Pp: 1271-1285
K. Labuzek, K. Gorki, H. Jaroszek, K. Jarzabek, B. Gabryel and B. Okopien
DOI: 10.2174/18715273113129990109
Published on: 27 August, 2013

Acknowledgements to Reviewers:

Volume:12   Issue: 8
Pp: 1286-1286

DOI: 10.2174/187152731208140102225512
Published on: 02 January, 2014