CNS & Neurological Disorders - Drug Targets

Formerly Current Drug Targets - CNS & Neurological Disorders


Edoardo Spina
Department of Clinical and Experimental Medicine
University of Messina
Policlinico Universitario
Via Consolare Valeria

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Volume: 12 Issue: 6, September 2013

Conference Report:

Volume:12   Issue: 6
Pp: 715-716
Stephen D. Skaper
DOI: 10.2174/1871527311312060001
Published on: 20 September, 2013

Commentary: (Research Highlights: “MiRNAcles” in Brain)

Volume:12   Issue: 6
Pp: 717-718
Chiara Parisi and Cinzia Volonté
DOI: 10.2174/18715273113126660180
Published on: 19 September, 2013

Editorial (Thematic Issue: Microglia - A Therapeutic Target in Neurological Diseases and Disorders) free to download

Volume:12   Issue: 6
Pp: 719-719
Charanjit Kaur and Eng-Ang Ling
DOI: 10.2174/18715273113126660179
Published on: 20 September, 2013

Role of Microglia in the Pathogenesis of Sepsis-Associated Encephalopathy

Volume:12   Issue: 6
Pp: 720-725
Y.Y. Deng, M. Fang, G.F. Zhu, Y. Zhou and H.K. Zeng
DOI: 10.2174/18715273113126660178
Published on: 19 September, 2013

A Friend in Need May Not be a Friend Indeed: Role of Microglia in Neurodegenerative Diseases

Volume:12   Issue: 6
Pp: 726-740
Deepak Kumar Kaushik and Anirban Basu
DOI: 10.2174/18715273113126660170
Published on: 18 September, 2013

Screening for Inhibitors of Microglia to Reduce Neuroinflammation

Volume:12   Issue: 6
Pp: 741-749
Shazia Samanani, Manoj Mishra, Claudia Silva, Brooke Verhaeghe, Janet Wang, Jade Tong and V. Wee Yong
DOI: 10.2174/18715273113126660177
Published on: 19 September, 2013

The Potential for Genetically Altered Microglia to Influence Glioma Treatment

Volume:12   Issue: 6
Pp: 750-762
W. Li, R.M.D. Holsinger, C.A. Kruse, A. Flügel and M.B. Graeber
DOI: 10.2174/18715273113126660171
Published on: 18 September, 2013

Microglial Senescence

Volume:12   Issue: 6
Pp: 763-767
Wolfgang J. Streit and Qing-Shan Xue
DOI: 10.2174/18715273113126660176
Published on: 19 September, 2013

Microglia and Neuropathic Pain

Volume:12   Issue: 6
Pp: 768-772
Håkan Aldskogius and Elena N. Kozlova
DOI: 10.2174/18715273113126660168
Published on: 18 September, 2013

Glutamate Receptors in Microglia open access plus

Volume:12   Issue: 6
Pp: 773-784
Madhuvika Murugan, Eng-Ang Ling and Charanjit Kaur
DOI: 10.2174/18715273113126660174
Published on: 19 September, 2013

Consequences of Iron Accumulation in Microglia and its Implications in Neuropathological Conditions

Volume:12   Issue: 6
Pp: 785-798
Gurugirijha Rathnasamy, Eng-Ang Ling and Charanjit Kaur
DOI: 10.2174/18715273113126660169
Published on: 18 September, 2013

Potential Drugs Targeting Microglia: Current Knowledge and Future Prospects

Volume:12   Issue: 6
Pp: 799-806
Parakalan Rangarajan, Ling Eng-Ang and S. Thameem Dheen
DOI: 10.2174/18715273113126660175
Published on: 19 September, 2013

Notch Signaling in the Central Nervous System with Special Reference to its Expression in Microglia

Volume:12   Issue: 6
Pp: 807-814
Linli Yao, Qiong Cao, Chunyun Wu, Charanjit Kaur, Aijun Hao and Eng-Ang Ling
DOI: 10.2174/18715273113126660172
Published on: 19 September, 2013

Relationship Between the Chemokine Receptor CCR5 and Microglia in Neurological Disorders: Consequences of Targeting CCR5 on Neuroinflammation, Neuronal Death and Regeneration in a Model of Epilepsy open access plus

Volume:12   Issue: 6
Pp: 815-829
Jean-Pierre Louboutin and David S. Strayer
DOI: 10.2174/18715273113126660173
Published on: 19 September, 2013

Interplay Between Cholesterol and Homocysteine in the Exacerbation of Amyloid-β Toxicity in Human Neuroblastoma Cells

Volume:12   Issue: 6
Pp: 842-848
Aydé Mendoza-Oliva, Patricia Ferrera and Clorinda Arias
DOI: 10.2174/18715273113129990083
Published on: 09 July, 2013

Alteration of Isocitrate Dehydrogenase Following Acute Ischemic Injury as a Means to Improve Cellular Energetic Status in Neuroadaptation

Volume:12   Issue: 6
Pp: 849-860
Kimberly N. Grelli, Amy M. Palubinsky, A. Cozette Kale, Britney N. Lizama-Manibusan, Jeannette N. Stankowski, Ginger L. Milne, Robert Singer and BethAnn McLaughlin
DOI: 10.2174/18715273113129990062
Published on: 12 April, 2013

Improving the Treatment of Schizophrenia: Role of 5-HT Receptors in Modulating Cognitive and Extrapyramidal Motor Functions

Volume:12   Issue: 6
Pp: 861-869
Saki Shimizu, Yuto Mizuguchi and Yukihiro Ohno
DOI: 10.2174/18715273113129990088
Published on: 09 July, 2013

Vascular Oxidative Stress and Mitochondrial Failure in the Pathobiology of Alzheimer’s Disease: A New Approach to Therapy

Volume:12   Issue: 6
Pp: 870-881
Marta Sochocka, Euphrosyni S. Koutsouraki, Kazimierz Gasiorowski and Jerzy Leszek
DOI: 10.2174/18715273113129990072
Published on: 28 June, 2013

Hierarchical Profiles of Signaling Pathways and Networks Reveal Two Complementary Pharmacological Mechanisms

Volume:12   Issue: 6
Pp: 882-893
Yinying Chen, Fanyun Meng, Hong Fang, Yanan Yu, Jun Liu, Zhiwei Jing, Aiping Lv, Zhong Wang and Yongyan Wang
DOI: 10.2174/18715273113129990073
Published on: 28 June, 2013