CNS & Neurological Disorders - Drug Targets

Formerly Current Drug Targets - CNS & Neurological Disorders


Edoardo Spina
Department of Clinical and Experimental Medicine
University of Messina
Policlinico Universitario
Via Consolare Valeria

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Volume: 12 Issue: 3, May 2013

Conference Report (3rd GTC Congress Report on Ubiquitin & Drug Discovery Feb 25-26, Palms Casino Resort, Las Vegas, NV, USA)

Volume:12   Issue: 3
Pp: 295-297
Hari Shanker Sharma and Aruna Sharma
DOI: 10.2174/1871527311312030001
Published on: 08 May, 2013

Commentary (Research Highlights: Linking Productive Autophagy to Neuroprotection: Potential Implications for Anti-Ischemic Therapy)

Volume:12   Issue: 3
Pp: 298-299
G.K. Rajanikant and Sinoy Sugunan
DOI: 10.2174/1871527311312030002
Published on: 08 May, 2013

Editorial (Hot Topic: Neuroprotection Against Stroke and CNS Injury: New Mechanisms, Targets, and Controversies)

Volume:12   Issue: 3
Pp: 300-301
Rehana K. Leak and Jun Chen
DOI: 10.2174/1871527311312030003
Published on: 08 May, 2013

Biphasic Mechanisms of Neurovascular Unit Injury and Protection in CNS Diseases

Volume:12   Issue: 3
Pp: 302-315
Takakuni Maki, Kazuhide Hayakawa, Loc-Duyen D. Pham, Changhong Xing, Eng H. Lo and Ken Arai
DOI: 10.2174/1871527311312030004
Published on: 08 May, 2013

The Role of Fatty Acids in the Regulation of Cerebral Vascular Function and Neuroprotection in Ischemia

Volume:12   Issue: 3
Pp: 316-324
Hung Wen Lin and Miguel Perez-Pinzon
DOI: 10.2174/1871527311312030005
Published on: 08 May, 2013

HSP27 Protects the Blood-Brain Barrier Against Ischemia-Induced Loss of Integrity open access plus

Volume:12   Issue: 3
Pp: 325-337
Rehana K. Leak, Lili Zhang, R. Anne Stetler, Zhongfang Weng, Peiying Li, G. Brandon Atkins, Yanqin Gao and Jun Chen
DOI: 10.2174/1871527311312030006
Published on: 08 May, 2013

Age-Dependent Microglial Activation in Immature Brains After Hypoxia- Ischemia

Volume:12   Issue: 3
Pp: 338-349
Peter Ferrazzano, Vishal Chanana, Kutluay Uluc, Emin Fidan, Erinc Akture, Douglas B. Kintner, Pelin Cengiz and Dandan Sun
DOI: 10.2174/1871527311312030007
Published on: 08 May, 2013

Ischemic Post-Conditioning Partially Reverses Cell Cycle Reactivity Following Ischemia/Reperfusion Injury: A Genome-Wide Survey

Volume:12   Issue: 3
Pp: 350-359
Haiping Zhao, Yumin Luo, Xiangrong Liu, Rongliang Wang, Feng Yan, Xiaomeng Liu, Sijie Li, Rehana K. Leak and Xunming Ji
DOI: 10.2174/1871527311312030008
Published on: 08 May, 2013

TrkB Receptor Agonist 7, 8 Dihydroxyflavone Triggers Profound Gender- Dependent Neuroprotection in Mice After Perinatal Hypoxia and Ischemia

Volume:12   Issue: 3
Pp: 360-370
Kutluay Uluc, Pınar Kendigelen, Emin Fidan, Louise Zhang, Vishal Chanana, Douglas Kintner, Erinc Akture, Chihwa Song, Keqiang Ye, Dandan Sun, Peter Ferrazzano and Pelin Cengiz
DOI: 10.2174/18715273113129990061
Published on: 08 May, 2013

Drug-Induced Hypothermia in Stroke Models: Does it Always Protect?

Volume:12   Issue: 3
Pp: 371-380
Meijuan Zhang, Haiying Wang, Jinbing Zhao, Cong Chen, Rehana K. Leak, Yun Xu, Peter Vosler, Jun Chen, Yanqin Gao and Feng Zhang
DOI: 10.2174/1871527311312030010
Published on: 08 May, 2013

miR-15b Suppression of Bcl-2 Contributes to Cerebral Ischemic Injury and is Reversed by Sevoflurane Preconditioning

Volume:12   Issue: 3
Pp: 381-391
Hong Shi, Bao-liang Sun, Jia Zhang, Shiduo Lu, Pengyue Zhang, Hailian Wang, Qiong Yu, R. Anne Stetler, Peter S. Vosler, Jun Chen and Yanqin Gao
DOI: 10.2174/1871527311312030011
Published on: 08 May, 2013

Adhesion Molecules in CNS Disorders: Biomarker and Therapeutic Targets

Volume:12   Issue: 3
Pp: 392-404
Qingyi Ma, Sheng Chen, Damon Klebe, John H. Zhang and Jiping Tang
DOI: 10.2174/1871527311312030012
Published on: 08 May, 2013

The Battle of the Sexes for Stroke Therapy: Female- Versus Male-Derived Stem Cells

Volume:12   Issue: 3
Pp: 405-412
Yuji Kaneko, Mibel M. Pabon, Travis Dailey, Nathan L. Weinbren, Jessica Rizzi, Cyrus Tamboli, Julianne Vasconcellos, Nicole Kuzmin-Nichols, Paul R. Sanberg, David J. Eve, Naoki Tajiri and Cesar V. Borlongan
DOI: 10.2174/1871527311312030013
Published on: 08 May, 2013

Neurorestorative Effect of Urinary Bladder Matrix-Mediated Neural Stem Cell Transplantation Following Traumatic Brain Injury in Rats open access plus

Volume:12   Issue: 3
Pp: 413-425
J.Y. Wang, A.K.F. Liou, Z.H. Ren, L. Zhang, B.N. Brown, X.T. Cui, S.F. Badylak, Y.N. Cai, Y.Q. Guan, Rehana K. Leak, J. Chen, X. Ji and L. Chen
DOI: 10.2174/1871527311312030014
Published on: 08 May, 2013

Does Mechanism of Drug Action Matter to Inform Rational Polytherapy in Epilepsy?

Volume:12   Issue: 3
Pp: 426-435
Giorgia Giussani and Ettore Beghi
DOI: 10.2174/1871527311312030015
Published on: 08 May, 2013

Inhibition of Glycogen Synthase Kinase-3 Reverses Tau Hyperphosphorylation Induced by Pin1 Down-Regulation

Volume:12   Issue: 3
Pp: 436-443
Yan-Si Xiong, Dan-Li Wang, Lu Tan, Xiong Wang, Li-Ming Chen, Cheng-Xin Gong, Jian-Zhi Wang and Ling-Qiang Zhu
DOI: 10.2174/1871527311312030016
Published on: 08 May, 2013

Expression of Concern

Volume:12   Issue: 3
Pp: 444-444

DOI: 10.2174/1871527311312030017
Published on: 08 May, 2013