CNS & Neurological Disorders - Drug Targets

Formerly Current Drug Targets - CNS & Neurological Disorders


Edoardo Spina
Department of Clinical and Experimental Medicine
University of Messina
Policlinico Universitario
Via Consolare Valeria

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Volume: 11 Issue: 8, December 2013

Conference Report (11th International Conference on Neuroprotective Agents, Wendake, Quebec City, Quebec, Canada, Sept 30-Oct 3, 2012)

Volume:11   Issue: 8
Pp: 951-952
Hari S. Sharma, Aruna Sharma and Stephen Skaper
DOI: 10.2174/1871527311211080001
Published on: 11 January, 2013

Commentary (Research Highlights Utilizing Neuro-Inflammation: Turning Degeneration to Regeneration)

Volume:11   Issue: 8
Pp: 953-954
Ying Cui, Jiang Li, Oscar Arias-Carrión and Ti-Fei Yuan
DOI: 10.2174/1871527311211080002
Published on: 11 January, 2013

Editorial (Hot Topic: Model System Caenorhabditis elegans and Neurodegenerative Disease Research)

Volume:11   Issue: 8
Pp: 955-956
Aamir Nazir
DOI: 10.2174/1871527311211080003
Published on: 11 January, 2013

C. elegans as a Genetic Model System to Identify Parkinson's Disease- Associated Therapeutic Targets

Volume:11   Issue: 8
Pp: 957-964
Julia Vistbakka, Natalia VanDuyn, Garry Wong and Richard Nass
DOI: 10.2174/1871527311211080004
Published on: 11 January, 2013

Effects of α-Synuclein Overexpression in Transgenic Caenorhabditis elegans Strains open access plus

Volume:11   Issue: 8
Pp: 965-975
Rakesh Bodhicharla, Archana Nagarajan, Jody Winter, Ademola Adenle, Aamir Nazir, Declan Brady, Kelly Vere, Jo Richens, Paul O’Shea, David R. Bell and David de Pomerai
DOI: 10.2174/1871527311211080005
Published on: 11 January, 2013

Environmental Toxicants as Extrinsic Epigenetic Factors for Parkinsonism: Studies Employing Transgenic C. elegans Model

Volume:11   Issue: 8
Pp: 976-983
Pooja Jadiya and Aamir Nazir
DOI: 10.2174/1871527311211080006
Published on: 11 January, 2013

Iridoid Compound 10-O-trans-p-Coumaroylcatalpol Extends Longevity and Reduces Alpha Synuclein Aggregation in Caenorhabditis elegans

Volume:11   Issue: 8
Pp: 984-992
Virendra Shukla, Suresh C. Phulara, Deepti Yadav, Sudeep Tiwari, Supinder Kaur, M. M. Gupta, Aamir Nazir and Rakesh Pandey
DOI: 10.2174/1871527311211080007
Published on: 11 January, 2013

Elicitation of Dopaminergic Features of Parkinson’s Disease in C. elegans by Monocrotophos, an Organophosphorous Insecticide

Volume:11   Issue: 8
Pp: 993-1000
Shaheen Jafri Ali and Padmanabhan Sharda Rajini
DOI: 10.2174/1871527311211080008
Published on: 11 January, 2013

Effect of Various Classes of Pesticides on Expression of Stress Genes in Transgenic C. elegans Model of Parkinson’s Disease

Volume:11   Issue: 8
Pp: 1001-1005
Pooja Jadiya, Snober S. Mir and Aamir Nazir
DOI: 10.2174/1871527311211080009
Published on: 11 January, 2013

An Overview on Potential Neuroprotective Compounds for Management of Alzheimer’s Disease

Volume:11   Issue: 8
Pp: 1006-1011
Ishfaq Ahmed Sheikh, Riyasat Ali, Tanveer A. Dar and Mohammad Amjad Kamal
DOI: 10.2174/1871527311211080010
Published on: 11 January, 2013

Frequency of Pituitary Tumor Apoplexy During Treatment of Prolactinomas with Dopamine Agonists: A Systematic Review

Volume:11   Issue: 8
Pp: 1012-1014
Robert Carija and Diana Vucina
DOI: 10.2174/1871527311211080011
Published on: 11 January, 2013

Nuclear Factor Erythroid 2 - Related Factor 2 Signaling in Parkinson Disease: A Promising Multi Therapeutic Target Against Oxidative Stress, Neuroinflammation and Cell Death open access plus

Volume:11   Issue: 8
Pp: 1015-1029
Hemant Kumar, Sushruta Koppula, In-Su Kim, Sandeep Vasant More, Byung-Wook Kim and Dong-Kug Choi
DOI: 10.2174/1871527311211080012
Published on: 11 January, 2013

The Protective Effects of Jatrorrhizine on β-Amyloid (25-35)-Induced Neurotoxicity in Rat Cortical Neurons

Volume:11   Issue: 8
Pp: 1030-1037
Tao Luo, Wei Jiang, Yan Kong, Sheng Li, Feng He, Jie Xu and Hua-Qiao Wang
DOI: 10.2174/1871527311211080013
Published on: 11 January, 2013

Functional Autoradiography Shows Unaltered Cannabinoid CB1 Receptor Signalling in Hippocampus and Cortex of APP/PS1 Transgenic Mice

Volume:11   Issue: 8
Pp: 1038-1044
E. Karkkainen, H. Tanila and J. T. Laitinen
DOI: 10.2174/1871527311211080014
Published on: 11 January, 2013

Geniposide Regulates Insulin-Degrading Enzyme Expression to Inhibit the Cytotoxicity of Aβ1-42 in Cortical Neurons

Volume:11   Issue: 8
Pp: 1045-1051
Fei Yin, Yonglan Zhang, Lixia Guo, Shuzhen Kong and Jianhui Liu
DOI: 10.2174/1871527311211080015
Published on: 11 January, 2013

Acetylcholinesterase Inhibitors as Pretreatment Before Acute Exposure to Organophosphates: Assessment Using Methyl-Paraoxon

Volume:11   Issue: 8
Pp: 1052-1060
Dietrich E. Lorke, Mohamed Y. Hasan, Syed M. Nurulain, Mohamed Shafiullah, Kamil Kuca and Georg A. Petroianu
DOI: 10.2174/1871527311211080016
Published on: 11 January, 2013

Restless Legs Syndrome in Multiple Sclerosis

Volume:11   Issue: 8
Pp: 1061-1069
Chiara Zecca, Mauro Manconi, Stephany Fulda and Claudio Gobbi
DOI: 10.2174/1871527311211080017
Published on: 11 January, 2013

Outcome-Dependent Global Similarity Analysis of Imbalanced Core Signaling Pathways in Ischemic Mouse Hippocampus

Volume:11   Issue: 8
Pp: 1070-1082
Jun Liu, Zhan-jun Zhang, Cai-xiu Zhou, Yi Wang, Yi-yu Cheng, Da-yue Darrel Duan, Yong-yan Wang and Zhong Wang
DOI: 10.2174/1871527311211080018
Published on: 11 January, 2013


Volume:11   Issue: 8
Pp: 1083-1083

DOI: 10.2174/1871527311211080019
Published on: 11 January, 2013