CNS & Neurological Disorders - Drug Targets

Formerly Current Drug Targets - CNS & Neurological Disorders


Edoardo Spina
Department of Clinical and Experimental Medicine
University of Messina
Policlinico Universitario
Via Consolare Valeria

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Editor's Choice

Nanoparticles Based Intranasal Delivery of Drug to Treat Alzheimer’s Disease: A Recent Update

Volume: 19   Issue: 9
Pp: 648-662
Manisha Pandey*, Hira Choudhury*, Rohit Kumar Verma, Viney Chawla, Subrat Kumar Bhattamisra, Bapi Gorain, Maria Abdul Ghafoor Raja and Muhammad Wahab Amjad
DOI: 10.2174/1871527319999200819095620

Fibrosis and Regulation of Nerve Regeneration in the Peripheral and Central Nervous Systems

Volume: 19   Issue: 8
Pp: 560-571
Nilabh Ghosh, Daniel Kalbermatten, Srinivas Madduri and Raphael Guzman*
DOI: 10.2174/1871527319666200726222558

Microbiota-Immune System Interactions in Human Neurological Disorders

Volume: 19   Issue: 7
Pp: 509-526
Qin Huang, Fang Yu, Di Liao and Jian Xia*
DOI: 10.2174/1871527319666200726222138

The MMP-2/TIMP-2 System in Alzheimer Disease

Volume: 19   Issue: 6
Pp: 402-416
Hongyue Wang, Longjian Huang, Lei Wu, Jiaqi Lan, Xinhong Feng, Pingping Li* and Ying Peng*
DOI: 10.2174/1871527319666200812223007

The locus of Action of CGRPergic Monoclonal Antibodies Against Migraine: Peripheral Over Central Mechanisms

Volume: 19   Issue: 5
Pp: 344-359
Abimael González-Hernández, Bruno A. Marichal-Cancino, Enrique García-Boll and Carlos M. Villalón*
DOI: 10.2174/1871527319666200618144637

MAPK: A Key Player in the Development and Progression of Stroke

Volume: 19   Issue: 4
Pp: 248-256
Yangmin Zheng, Ziping Han, Haiping Zhao and Yumin Luo*
DOI: 10.2174/1871527319666200613223018

Interlink Between Insulin Resistance and Neurodegeneration with an Update on Current Therapeutic Approaches

Volume: 19   Issue: 3
Pp: 174-183
Subrat Kumar Bhattamisra*, Lee Yuen Shin, Hanis Izzati Binti Mohd Saad, Vikram Rao, Mayuren Candasamy, Manisha Pandey and Hira Choudhury
DOI: 10.2174/1871527319666200518102130

Madecassic Acid Reduces Fast Transient Potassium Channels and Promotes Neurite Elongation in Hippocampal CA1 Neurons

Volume: 19   Issue: 1
Pp: 12-26
Sonia Siddiqui*, Faisal Khan , Khawar Saeed Jamali and Syed Ghulam Musharraf
DOI: 10.2174/1871527318666191111105508

Pharmacotherapy of Down’s Syndrome: When and Which?

Volume: 18   Issue: 10
Pp: 750-757
Seyed K. Tayebati*, Alessandro Cecchi, Ilenia Martinelli, Elisa Carboni and Francesco Amenta
DOI: 10.2174/1871527318666191114092924

Combined Ischemic Preconditioning and Resveratrol Improved Bloodbrain Barrier Breakdown via Hippo/YAP/TAZ Signaling Pathway

Volume: 18   Issue: 9
Pp: 713-722
Ganji Hong, Ying Yan, Yali Zhong, Jianer Chen, Fei Tong* and Qilin Ma*
DOI: 10.2174/1871527318666191021144126

Cordycepin Exerts Neuroprotective Effects via an Anti-Apoptotic Mechanism based on the Mitochondrial Pathway in a Rotenone-Induced Parkinsonism Rat Model

Volume: 18   Issue: 8
Pp: 609-620
Xin Jiang, Pei-Chen Tang, Qin Chen, Xin Zhang, Yi-Yun Fan, Bo-Cheng Yu, Xin-Xia Gu, Ying Sun, Xiao-Qun Ge* and Xiao-Ling Zhang*
DOI: 10.2174/1871527318666190905152138

Co-ultraPEALut: Role in Preclinical and Clinical Delirium Manifestations

Volume: 18   Issue: 7
Pp: 530-554
Maria Lia Lunardelli, Rosalia Crupi, Rosalba Siracusa, Giorgio Cocuzza, Marika Cordaro, Emilio Martini, Daniela Impellizzeri, Rosanna Di Paola and Salvatore Cuzzocrea*
DOI: 10.2174/1871527318666190617162041

The Effect of Vitamin D3 Supplementation on Serum BDNF, Dopamine, and Serotonin in Children with Attention-Deficit/Hyperactivity Disorder

Volume: 18   Issue: 6
Pp: 496-501
Marzieh Seyedi, Fatemeh Gholami, Mahsa Samadi, Mahmoud Djalali, Mohammad Effatpanah*, Mir Saeed Yekaninejad, Rezvan Hashemi, Mina Abdolahi, Maryam Chamari and Niyaz Mohammadzadeh Honarvar
DOI: 10.2174/1871527318666190703103709

Computational Protein-Protein Docking Reveals the Therapeutic Potential of Kunitz-type Venom against hKv1.2 Binding Sites

Volume: 18   Issue: 5
Pp: 382-404
Rida Khalid, Nighat Noureen, Mohammad Amjad Kamal and Sidra Batool*
DOI: 10.2174/1871527318666190319140204

Causes and Consequences of MicroRNA Dysregulation Following Cerebral Ischemia-Reperfusion Injury

Volume: 18   Issue: 3
Pp: 212-221
Fatemeh Forouzanfar, Mana Shojapour, Samira Asgharzade* and Elham Amini
DOI: 10.2174/1871527318666190204104629

Xuesaitong May Protect Against Ischemic Stroke by Modulating Microglial Phenotypes and Inhibiting Neuronal Cell Apoptosis via the STAT3 Signaling Pathway

Volume: 18   Issue: 2
Pp: 115-123
Fangfang Li, Haiping Zhao, Ziping Han, Rongliang Wang, Zhen Tao, Zhibin Fan, Sijia Zhang, Guangwen Li, Zhigang Chen* and Yumin Luo*
DOI: 10.2174/1871527317666181114140340

Motor Recovery after Chronic Spinal Cord Transection in Rats: A Proof-of-Concept Study Evaluating a Combined Strategy

Volume: 18   Issue: 1
Pp: 52-62
Antonio Ibarra*, Erika Mendieta-Arbesú, Paola Suarez-Meade, Elisa García-Vences, Susana Martiñón, Roxana Rodriguez-Barrera, Joel Lomelí, Adrian Flores-Romero, Raúl Silva-García, Vinnitsa Buzoianu-Anguiano, Cesar V. Borlongan and Tamara D. Frydman
DOI: 10.2174/1871527317666181105101756