Current Drug Discovery Technologies


Vladimir P. Torchilin
(68301 citations)
Department of Pharmaceutical Science Center for Pharmaceutical Biotechnology and Nanomedicine
Northeastern University
Boston, MA 02115

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Open Access Articles

Synthesis, Cytotoxicity Evaluation and Molecular Docking of Fluorine Containing Hexahydroquinoline-3-Carbonitrile Derivatives open Access plus

Volume: 18  
Pp: 1-11
Nishith Teraiya*, Subhas Karki and Ashlesha Chauhan

Potential Fatty Acid as Antibacterial Agent Against Oral Bacteria of Streptococcus mutans and Streptococcus sanguinis from Basil (Ocimum americanum): In vitro and in silico Studies open Access plus

Volume: 17  
Pp: 1-10
Yetty Herdiyati, Yonada Astrid, Aldina Amalia Nur Shadrina, Ika Wiani, Mieke Hemiawati Satari and Dikdik Kurnia*

Structure-Based Docking Studies of GLUT4 Towards Exploring Selected Phytochemicals from Solanum xanthocarpum as a Therapeutic Target for the Treatment of Cancer open Access plus

Volume: 16   Issue: 4
Pp: 406-416
Babatunji Emmanuel Oyinloye*, Tayo Alex Adekiya, Raphael Taiwo Aruleba, Oluwafemi Adeleke Ojo and Basiru Olaitan Ajiboye

The Modulatory Effect of Lead Drug Candidates on Inflammatory Gene Expression in Sepsis: A Mini-Review open Access plus

Volume: 16   Issue: 1
Pp: 48-56
Samuel Mawuli Adadey*, Michael Bright Yakass, Seth Agyemang and Samuel Duodu

Date Palm (Phoenix dactylifera): Novel Findings and Future Directions for Food and Drug Discovery open Access plus

Volume: 16   Issue: 1
Pp: 2-10
Ali H. El-Far*, Babatunji E. Oyinloye, Masood Sepehrimanesh, Mahmoud A. Gab Allah, Ibrahim Abu-Reidah, Hazem M. Shaheen, Iman Razeghian-Jahromi, Abd el-wahab A. Alsenosy, Ahmed E. Noreldin, Soad K. Al Jaouni and Shaker A. Mousa*

The Development of New Factor Xa Inhibitors Based on Amide Synthesis open Access plus

Volume: 15   Issue: 4
Pp: 335-350
Dmitry N. Tarasov, Dmitry G. Tovbin, Dmitry V. Malakhov, Arseniy V. Aybush, Natalia A. Tserkovnikova, Marina I. Savelyeva, Dmitry A. Sychev, Natalia N. Drozd* and Alla Y. Savchenko

Pimping up Drugs Recovered, Superannuated and Under Exploited Drugs - An Introduction to the Basics of Drug Reprofiling open Access plus

Volume: 14   Issue: 2
Pp: 121-126
Suzanne J. Dilly* and George S. Morris

Possible Anticancer Mechanisms of Some Costus speciosus Active Ingredients Concerning Drug Discovery open Access plus

Volume: 13   Issue: 3
Pp: 123-143
Ali H. El-Far, Faried A. Badria and Hazem M. Shaheen

Can EGFR-Tyrosine Kinase Inhibitors (TKI) Alone Without Talc Pleurodesis Prevent Recurrence of Malignant Pleural Effusion (MPE) in Lung Adenocarcinoma open Access plus

Volume: 13   Issue: 2
Pp: 68-76
Akash Verma, Akhil Chopra, Yeo W. Lee, Lavina D. Bharwani, Atasha B. Asmat, Dokeu B.A Aneez, Fazuludeen A. Akbar, Albert Y.H. Lim, Sanjay H. Chotirmall and John Abisheganaden

Quantitative Structure-Cytotoxic Activity Relationship 1-(Benzoyloxy)urea and Its Derivative open Access plus

Volume: 13   Issue: 2
Pp: 101-108
Suko Hardjono, Siswandono Siswodihardjo, Purwanto Pramono and Win Darmanto

Sodium-Assisted Formation of Binding and Traverse Conformations of the Substrate in a Neurotransmitter Sodium Symporter Model open Access plus

Volume: 11   Issue: 3
Pp: 227-233
Agnes Simon, Akos Bencsura, Laszlo Heja, Csaba Magyar and Julianna Kardos

The Importance of Epitope Binning for Biological Drug Discovery open Access plus

Volume: 11   Issue: 2
Pp: 109-112
Benjamin D. Brooks

On the Mechanism of Action of Antipsychotic Drugs: A Chemical Reaction Not Receptor Blockade open Access plus

Volume: 10   Issue: 3
Pp: 195-208
Christine L. Miller

Potential Therapeutic Application of Chondroitin Sulfate/Dermatan Sulfate open Access plus

Volume: 5   Issue: 4
Pp: 289-301
Shuhei Yamada and Kazuyuki Sugahara