Current Drug Discovery Technologies


Vladimir P. Torchilin
(68301 citations)
Department of Pharmaceutical Science Center for Pharmaceutical Biotechnology and Nanomedicine
Northeastern University
Boston, MA 02115

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The Nuclear Overhauser Effect in the Lead Identification Process Pharmacophore Models

Volume:3   Issue: 2
Pp: 91-100
Marilisa Leone, Hudson H. Freeze, Chui Sien Chan and Maurizio Pellecchia
DOI: 10.2174/157016306778108884

Mechanism Study of N-Dephenylation Mediated through a N-para-Hydroxy Metabolite

Volume:3   Issue: 2
Pp: 101-114
Jianyao Wang, William DeMaio, Appavu Chandrasekaran, Li Shen, Alvin C. Bach II, JoAnn Scatina and Rasmy Talaat
DOI: 10.2174/157016306778108901

NMR-Based Quality Control Approach for the Identification of False Positives and False Negatives in High Throughput Screening

Volume:3   Issue: 2
Pp: 115-124
Claudio Dalvit, Dannica Caronni, Nicola Mongelli, Marina Veronesi and Anna Vulpetti
DOI: 10.2174/157016306778108875

Novel Anti-bacterials Against MRSA: Synthesis of Focussed Combinatorial Libraries of Tri-Substituted 2(5H)-Furanones

Volume:3   Issue: 2
Pp: 125-134
Eric Lattmann, Nison Sattayasai, Carl S. Schwalbe, Suwanna Niamsanit, David C. Billington, Pornthip Lattmann, Christopher A. Langley, Harjit Singh and Simon Dunn
DOI: 10.2174/157016306778108857

Selective Targeting of Liposomes to Macrophages Using a Ligand with High Affinity for the Macrophage Scavenger Receptor Class A

Volume:3   Issue: 2
Pp: 135-144
Patrick C.N. Rensen, J.C. Emile Gras, Eva K. Lindfors, Ko Willems van Dijk, J. Wouter Jukema, Theo J.C. van Berkel and Erik A.L. Biessen
DOI: 10.2174/157016306778108893

Protein Conformational Diseases: From Mechanisms to Drug Designs

Volume:3   Issue: 2
Pp: 145-153
Jin-Chung Lin and Hsuan-Liang Liu
DOI: 10.2174/157016306778108866