Current Drug Discovery Technologies

Editor-in-Chief

Vladimir P. Torchilin
(68301 citations)
Department of Pharmaceutical Science Center for Pharmaceutical Biotechnology and Nanomedicine
Northeastern University
Boston, MA 02115
(USA)

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Volume:17   Issue: 5
Pp: 563-564
Igor I. Baskin
DOI: 10.2174/157016381705201223150220
Published on: 23 December, 2020



Drug Stereochemistry: A Prodigy For Pharmacology and Drug Development

Volume:17   Issue: 5
Pp: 565-573
Karan Gandhi, Umang Shah* and Sandip Patel
DOI: 10.2174/1570163816666190502101803
Published on: 23 December, 2020




Biological Significance of Imidazole-based Analogues in New Drug Development

Volume:17   Issue: 5
Pp: 574-584
Pratiksha N. Chopra and Jagdish K. Sahu*
DOI: 10.2174/1570163816666190320123340
Published on: 23 December, 2020




Targeting Small Molecule Tyrosine Kinases by Polyphenols: New Move Towards Anti-tumor Drug Discovery

Volume:17   Issue: 5
Pp: 585-615
Nikhil S. Sakle, Shweta A. More, Sachin A. Dhawale and Santosh N. Mokale*
DOI: 10.2174/1570163816666190808120843
Published on: 23 December, 2020




Statins as the Controlling Agents for Non-Hodgkin's Lymphomas via Increasing the Casein Kinase 2 Interacting Protein-1: A Hypothesis

Volume:17   Issue: 5
Pp: 616-618
Kimia Kazemi, Negin Mozafari, Hajar Ashrafi, Pedram Rafiei and Amir Azadi*
DOI: 10.2174/1570163816666190628165200
Published on: 23 December, 2020




Virtual Structural Similarity Elucidates Bioactivity of Fenchone: A Phytochemical Enriched in Fennel Essential Oil

Volume:17   Issue: 5
Pp: 619-630
Sukhchain Singh*, Pawan Gupta and Jeena Gupta*
DOI: 10.2174/1570163816666190321142826
Published on: 23 December, 2020




Design, Synthesis and Anticancer Activity of Site Specific Short Chain Cationic Peptide

Volume:17   Issue: 5
Pp: 631-646
Ravi D. Sharma*, Jainendra Jain and Ratan L. Khosa
DOI: 10.2174/1570163816666190402121033
Published on: 23 December, 2020




Exploring the Potential of Capsaicin Against Cancer Metastasis Based on TGF-β Signaling Modulation Through Module-based Network Pharmacology Approach

Volume:17   Issue: 5
Pp: 647-660
Shivananda Kandagalla, Sharath Belenahalli Shekarappa, Gollapalli Pavan, Umme Hani and Manjunatha Hanumanthappa*
DOI: 10.2174/1570163816666190515104041
Published on: 23 December, 2020




Photochemical /Photocytotoxicity Studies of New Tetrapyrrolic Structures as Potential Candidates for Cancer Theranostics

Volume:17   Issue: 5
Pp: 661-669
Luis F. Vieira Ferreira*, Isabel Ferreira Machado, Ana Gama, Radu P. Socoteanu, Rica Boscencu, Gine Manda, Ricardo C. Calhelha and Isabel C.F.R. Ferreira
DOI: 10.2174/1570163816666190411100919
Published on: 23 December, 2020




Interaction with Modified Cyclodextrin as a Way to Increase the Antimalarial Activity of Primaquine

Volume:17   Issue: 5
Pp: 670-681
Liliane Henrique Torres, Lucas Bragança de Carvalho, Adneia de Fátima Abreu Venceslau, Carlos Jaime and Luciana de Matos Alves Pinto*
DOI: 10.2174/1570163816666190719154258
Published on: 23 December, 2020




Kaempferol as a Potential PAK4 Inhibitor in Triple Negative Breast Cancer: Extra Precision Glide Docking and Free Energy Calculation

Volume:17   Issue: 5
Pp: 682-695
Michael A. Arowosegbe*, Oluwamuyiwa T. Amusan, Segun A. Adeola, Oluwatosin B. Adu, Israel A. Akinola, Bimpe F. Ogungbe, Olaposi I. Omotuyi, Gbemisola M. Saibu, Adewale J. Ogunleye, Ramon I. Kanmodi, Nekabari E. Lugbe, Oluwafemi J. Ogunmola, Damilola C. Ajayi, Sedoten O. Ogun, Faith O. Oyende, Ahmed O. Bello, Peter G. Ishola and Patrick E. Obasieke
DOI: 10.2174/1570163816666190823135948
Published on: 23 December, 2020




The Effect of Viola Odorata L. Oil for Fever in Children: A Randomized Triple-blinded Placebo-controlled Clinical Trial

Volume:17   Issue: 5
Pp: 696-703
Vahid Tafazoli, Mahdi Shahriari, Mojtaba Heydari, Hosein Ali Nikbakht, Mohammad M. Zarshenaas and Majid Nimrouzi*
DOI: 10.2174/1570163816666190620142256
Published on: 23 December, 2020




The Oral Administration Effect of Drug Mannuronic Acid (M2000) on Gene Expression of Matrix and Tissue Inhibitor of Metalloproteinases in Rheumatoid Arthritis Patients

Volume:17   Issue: 5
Pp: 704-710
Nada A.G. Gaafar, Mona Aslani, Zahra Aghazadeh, Alireza Razavi and Abbas Mirshafiey*
DOI: 10.2174/1570163816666190620113320
Published on: 23 December, 2020




The Parsnip (Pastinaca sativa L), A Proposed Remedy as to a Fertile Agent in the Viewpoint of Iranian Traditional Medicine

Volume:17   Issue: 5
Pp: 711-715
Fatemeh Hakimi*, Mojgan Tansaz and Roshanak Mokaberinejad
DOI: 10.2174/1570163816666190820143052
Published on: 23 December, 2020




Large-scale High-throughput Screening Revealed 5'-(carbonylamino)-2,3'- bithiophene-4'-carboxylate as Novel Template for Antibacterial Agents

Volume:17   Issue: 5
Pp: 716-724
Yan A. Ivanenkov, Renat S. Yamidanov, Ilya A. Osterman, Petr V. Sergiev, Vladimir A. Aladinskiy, Anastasia V. Aladinskaya, Victor A. Terentiev, Mark S. Veselov, Andrey A. Ayginin, Dmitry A. Skvortsov, Katerina S. Komarova, Bogdan A. Zagribelnyy*, Alexey Kh. Baimiev, Kseniya Yu. Shvetc, Andrey Kh. Baimiev, Alina A. Sofronova, Alexey E. Machulkin, Rostislav A. Petrov, Liana F. Zainullina, Marina A. Maximova, Zulfiya R. Zileeva, Yulia V. Vakhitova, Dmitry S. Bezrukov, Maria M. Puchinina and Olga A. Dontsova
DOI: 10.2174/1570163816666190603095521
Published on: 23 December, 2020




In Silico Screening Reveals Histone Deacetylase 7 and ERK1/2 as Potential Targets for Artemisinin Dimer and Artemisinin Dimer Hemisuccinate

Volume:17   Issue: 5
Pp: 725-734
Ahmed A. Ishola and Kayode E. Adewole*
DOI: 10.2174/1570163816666190705164756
Published on: 23 December, 2020




Zebra Fish in Toxicology Research: Streptavidin Conjugated Peroxidase Assay in the Development Phase of Zebrafish Embryos to Study Liver Toxicities

Volume:17   Issue: 5
Pp: 735-739
Asis Bala*, Chaitali Mondal and Pallab KantiHaldar
DOI: 10.2174/1570163816666190801120016
Published on: 23 December, 2020




A Definitive Pharmacophore Modelling Study on CDK2 ATP Pocket Binders: Tracing the Path of New Virtual High-Throughput Screenings

Volume:17   Issue: 5
Pp: 740-747
Marco Tutone*, Giulia Culletta, Luca Livecchi and Anna M. Almerico
DOI: 10.2174/1570163816666190620113944
Published on: 23 December, 2020




Acknowledgements to Reviewers free to download

Volume:17   Issue: 5
Pp: 748-748

DOI: 10.2174/157016381705201223150450
Published on: 23 December, 2020