Current Drug Discovery Technologies


Vladimir P. Torchilin
(68301 citations)
Department of Pharmaceutical Science Center for Pharmaceutical Biotechnology and Nanomedicine
Northeastern University
Boston, MA 02115

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Volume: 11 Issue: 1, March 2014

Editorial (Thematic Issue: Modern Therapeutic Antibody Drug Discovery Technologies) free to download

Volume:11   Issue: 1
Pp: 1-2
William R. Strohl
DOI: 10.2174/157016381101140124160256

Antibody Discovery: Sourcing of Monoclonal Antibody Variable Domains

Volume:11   Issue: 1
Pp: 3-19
William R. Strohl
DOI: 10.2174/1570163810666131120150043

Isolation of Antibodies From Non-Human Primates for Clinical Use

Volume:11   Issue: 1
Pp: 20-27
Arnaud Avril, Jeffrey W. Froude, Jacques Mathieu, Thibaut Pelat and Philippe Thullier
DOI: 10.2174/15701638113109990030

Discovery of Novel Candidate Therapeutics and Diagnostics Based on Engineered Human Antibody Domains

Volume:11   Issue: 1
Pp: 28-40
Weizao Chen, Rui Gong, Tianlei Ying, Ponraj Prabakaran, Zhongyu Zhu, Yang Feng and Dimiter S. Dimitrov
DOI: 10.2174/15701638113109990032

Different Approaches for Obtaining Antibodies from Human B Cells

Volume:11   Issue: 1
Pp: 41-47
Marcus R. Duvall and Ryan N. Fiorini
DOI: 10.2174/1570163811666140121154649

Antibody Library Display on a Mammalian Virus Vector: Combining the Advantages of Both Phage and Yeast Display into One Technology

Volume:11   Issue: 1
Pp: 48-55
Ernest S. Smith and Maurice Zauderer
DOI: 10.2174/157016381101140124163634

Mammalian Cell Display and Somatic Hypermutation In Vitro for Human Antibody Discovery

Volume:11   Issue: 1
Pp: 56-64
David J. King, Peter M. Bowers, Marilyn R. Kehry and Robert A. Horlick
DOI: 10.2174/15701638113109990037

Antibody Discovery from Immune Competent and Immune Transplanted Mice

Volume:11   Issue: 1
Pp: 65-73
Benjamin C. Harman, Jill Giles-Komar and Michael A. Rycyzyn
DOI: 10.2174/15701638113109990036

Transgenic Mouse Strains as Platforms for the Successful Discovery and Development of Human Therapeutic Monoclonal Antibodies

Volume:11   Issue: 1
Pp: 74-84
Larry L. Green
DOI: 10.2174/15701638113109990038

Deep Sequencing Approaches to Antibody Discovery

Volume:11   Issue: 1
Pp: 85-95
Michael F. Naso, Jin Lu and Tadas Panavas
DOI: 10.2174/15701638113106660040