Current Alzheimer Research


Prof. Debomoy K. Lahiri
(16607 citations)
Neuroscience Research Center
Indianapolis, IN 46202

Nobel Laureates on Editorial Board

Prof. Jean-Marie Lehn

Prof. Ferid Murad

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Development of Novel Amyloid Imaging Agents Based Upon Thioflavin S

Volume:2   Issue: 2
Pp: 109-114
Jingjun Wei, Chunying Wu, David Lankin, Anil Gulrati, Tibor Valyi-Nagy, Elizabeth Cochran, Victor W. Pike, Alan Kozikowski and Yanming Wang
DOI: 10.2174/1567205053585864

Towards Practical Cognitive Assessment for Detection of Early Dementia: A 30-Minute Computerized Battery Discriminates as Well as Longer Testing

Volume:2   Issue: 2
Pp: 117-124
Glen M. Doniger, David M. Zucker, Avraham Schweiger, Tzvi Dwolatzky, Howard Chertkow, Howard Crystal and Ely S. Simon
DOI: 10.2174/1567205053585792

C-1073 (Mifepristone) in the Adjunctive Treatment of Alzheimers Disease

Volume:2   Issue: 2
Pp: 125-129
Charles DeBattista and Joseph Belanoff
DOI: 10.2174/1567205053585954

A Potential Role of the Curry Spice Curcumin in Alzheimers Disease

Volume:2   Issue: 2
Pp: 131-136
John M. Ringman, Sally A. Frautschy, Gregory M. Cole, Donna L. Masterman and Jeffrey L. Cummings
DOI: 10.2174/1567205053585882

Synaptic Fatigue is More Pronounced in the APP/PS1 Transgenic Mouse Model of Alzheimers Disease

Volume:2   Issue: 2
Pp: 137-140
Hong Zhang, Bing Gong, Shumin Liu, Mauro Fa, Ipe Ninan, Agnieszka Staniszewski and Ottavio Arancio
DOI: 10.2174/1567205053585936

Functional Central Nicotinic Acetylcholine Receptor Antagonism by Systemic Administration of Tinuvin 770 (BTMPS)

Volume:2   Issue: 2
Pp: 141-147
John H. Graham, Roger L. Papke and Jerry J. Buccafusco
DOI: 10.2174/1567205053585747

Neurotrophin Receptor-Based Strategies for Alzheimers Disease

Volume:2   Issue: 2
Pp: 167-169
Frank M. Longo and Stephen M. Massa
DOI: 10.2174/1567205053585819

Nitric Oxide Mimetic Molecules as Therapeutic Agents in Alzheimers Disease

Volume:2   Issue: 2
Pp: 171-182
Gregory R.J. Thatcher, Brian M. Bennett and James N. Reynolds
DOI: 10.2174/1567205053585945

Small Molecule TGF-beta Mimetics as Potential Neuroprotective Factors

Volume:2   Issue: 2
Pp: 183-186
Hui Zhang, Kun Zou, Ina Tesseur and Tony Wyss-Coray
DOI: 10.2174/1567205053585756

Role of Fractalkine (CX3CL1) in Regulating Neuron-Microglia Interactions: Development of Viral-Based CX3CR1 Antagonists

Volume:2   Issue: 2
Pp: 187-189
Wolfgang J. Streit, Christopher N. Davis and Jeffrey K. Harrison
DOI: 10.2174/1567205053585765

Validation of the Neuroinflammation Cycle as a Drug Discovery Target Using Integrative Chemical Biology and Lead Compound Development with an Alzheimers Disease-Related Mouse Model

Volume:2   Issue: 2
Pp: 197-205
Wenhui Hu, Hantamalala Ralay Ranaivo, Jeffrey M. Craft, Linda J. Van Eldik and D. Martin Watterson
DOI: 10.2174/1567205053585828

Analysis of Genetic Polymorphisms in Acetylcholinesterase as Reflected in Different Populations

Volume:2   Issue: 2
Pp: 207-218
Yehudit Hasin, Nili Avidan, Dani Bercovich, Amos D. Korczyn, Israel Silman, Jacques S. Beckmann and Joel L. Sussman
DOI: 10.2174/1567205053585909

Screening for Inhibitors of Tau Polymerization

Volume:2   Issue: 2
Pp: 219-226
Marcus Pickhardt, Martin von Bergen, Zuzana Gazova, Antje Hascher, Jacek Biernat, Eva-Maria Mandelkow and Eckhard Mandelkow
DOI: 10.2174/1567205053585891

Cytoskeletal Integrity as a Drug Target

Volume:2   Issue: 2
Pp: 227-229
M. L. Michaelis, K. I. Seyb and S. Ansar
DOI: 10.2174/1567205053585837

Development of a High Throughput Drug Screening Assay for the Detection of Changes in Tau Levels - Proof of Concept with HSP90 inhibitors

Volume:2   Issue: 2
Pp: 231-238
Chad A. Dickey, Jason Eriksen, Adeela Kamal, Francis Burrows, Srinivas Kasibhatla, Christopher B. Eckman, Mike Hutton and Leonard Petrucelli
DOI: 10.2174/1567205053585927

Lentiviral Vector-Based Models of Amyloid Pathology: From Cells to Animals

Volume:2   Issue: 2
Pp: 239-247
Laura Shaughnessy, Mary Beth Thomas, John Wakefield, Beth Chamblin, Ayyappan Nair, Frank Koentgen and Ram Ramabhadran
DOI: 10.2174/1567205053585963

Pilot Study of the Reducing Effect on Amyloidosis In Vivo by Three FDA Pre-Approved Drugs Via the Alzheimers APP 5Untranslated Region

Volume:2   Issue: 2
Pp: 249-254
Stephanie Tucker, Michelle Ahl, Ashley Bush, David Westaway, Xudong Huang and Jack T. Rogers
DOI: 10.2174/1567205053585855

Drug Library Screen to Identify Compounds that Decrease Secreted Aβ from a Human Cell Line

Volume:2   Issue: 2
Pp: 255-259
Enakshi Chakrabarti and Jonathan D. Smith
DOI: 10.2174/1567205053585738

Recent Developments on the Studies of Human Memapsin 2 (β-Secretase)

Volume:2   Issue: 2
Pp: 261-264
Jordan Tang, Xiangyang He, Xianping Huang and Lin Hong
DOI: 10.2174/1567205053585800

An Aβ Sequestration Approach Using Non-Antibody Aβ Binding Agents

Volume:2   Issue: 2
Pp: 265-268
Yasuji Matsuoka, Li Shao, Manik Debnath, John LaFrancois, Amanda Becker, Audrey Gray, Paul Aisen, Chester Mathis, William Klunk and Karen Duff
DOI: 10.2174/1567205053585774

LRP-Mediated Clearance of Aβ is Inhibited by KPI-Containing Isoforms of APP

Volume:2   Issue: 2
Pp: 269-273
Robert D. Moir and Rudolph E. Tanzi
DOI: 10.2174/1567205053585918