Current Bioinformatics

Identification of Cancerlectins by Using Cascade Linear Discriminant Analysis and Optimal g-gap Tripeptide Composition

Volume: 15   Issue: 6
Pp: 528-537
Liangwei Yang , Hui Gao *, Keyu Wu, Haotian Zhang , Changyu Li and Lixia Tang
DOI: 10.2174/1574893614666190730103156

An in silico Immunogenicity Analysis for PbHRH: An Antiangiogenic Peptibody by fusing HRH Peptide and Human IgG1 Fc Fragment

Volume: 15   Issue: 6
Pp: 556-561
Lin Ning, Jiang Huang *, Bifang He and Juanjuan Kang
DOI: 10.2174/1574893614666190730104348

Improving Multi-type Gram-negative Bacterial Secreted Protein Prediction via Protein Evolutionary Information and Feature Ranking

Volume: 15   Issue: 6
Pp: 538-546
Liang Kong*, Lichao Zhang and Shiqian He
DOI: 10.2174/1574893614666190730105629

Predicting LncRNA Subcellular Localization Using Unbalanced Pseudo-k Nucleotide Compositions

Volume: 15   Issue: 6
Pp: 562-570
Xiao-Fei Yang, Yuan-Ke Zhou, Lin Zhang, Yang Gao* and Pu-Feng Du*
DOI: 10.2174/1574893614666190902151038

Integrating Second-order Moving Average and Over-sampling Algorithm to Predict Apoptosis Protein Subcellular Localization

Volume: 15   Issue: 6
Pp: 517-527
Yunyun Liang* and Shengli Zhang*
DOI: 10.2174/1574893614666190902155811

Analysis of the Epigenetic Signature of Cell Reprogramming by Computational DNA Methylation Profiles

Volume: 15   Issue: 6
Pp: 571-581
Yongchun Zuo*, Mingmin Song, Hanshuang Li, Xing Chen, Pengbo Cao, Lei Zheng and Guifang Cao*
DOI: 10.2174/1574893614666190919103752

Docking Techniques in Toxicology: An Overview

Volume: 15   Issue: 6
Pp: 600-610
Meenakshi Gupta, Ruchika Sharma and Anoop Kumar*
DOI: 10.2174/1574893614666191003125540

Using the Chou’s Pseudo Component to Predict the ncRNA Locations Based on the Improved K-nearest Neighbor (iKNN) Classifier

Volume: 15   Issue: 6
Pp: 582-592
Chengyan Wu*, Qianzhong Li, Ru Xing and Guo-Liang Fan
DOI: 10.2174/1574893614666191003142406

Complex Networks, Gene Expression and Cancer Complexity: A Brief Review of Methodology and Applications

Volume: 15   Issue: 6
Pp: 630-655
A.C. Iliopoulos, G. Beis, P. Apostolou and I. Papasotiriou*
DOI: 10.2174/1574893614666191017093504

The Regulation of Target Genes by Co-occupancy of Transcription Factors, c-Myc and Mxi1 with Max in the Mouse Cell Line

Volume: 15   Issue: 6
Pp: 547-555
Hui Wang, Yuan Liu, Hua Guan* and Guo-Liang Fan*
DOI: 10.2174/1574893614666191106103633

An Information Gain-based Method for Evaluating the Classification Power of Features Towards Identifying Enhancers

Volume: 15   Issue: 6
Pp: 593-599
Tianjiao Zhang, Rongjie Wang, Qinghua Jiang* and Yadong Wang*
DOI: 10.2174/1574893614666191120141032

Rosetta and the Journey to Predict Proteins’ Structures, 20 Years On

Volume: 15   Issue: 6
Pp: 611-629
Jad Abbass* and Jean-Christophe Nebel
DOI: 10.2174/1574893615999200504103643

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Volume: 15   Issue: 6
Pp: 515-516
Hao Lin
DOI: 10.2174/157489361506200610112345

Identification of Lysine Carboxylation Sites in Proteins by Integrating Statistical Moments and Position Relative Features via General PseAAC

Volume: 15   Issue: 5
Pp: 396-407
Saba Amanat, Adeel Ashraf, Waqar Hussain, Nouman Rasool and Yaser D. Khan*
DOI: 10.2174/1574893614666190723114923

The Human OncoBiome Database: A Database of Cancer Microbiome Datasets

Volume: 15   Issue: 5
Pp: 472-477
Nadia and Jayashree Ramana*
DOI: 10.2174/1574893614666190902152727

White Blood Cell Image Segmentation based on Color Component Combination and Contour Fitting

Volume: 15   Issue: 5
Pp: 463-471
Chuansheng Wang, Hong Zhang*, Zuoyong Li*, Xiaogen Zhou, Yong Cheng* and Rongyan Chen
DOI: 10.2174/1574893614666191017102310

Whole Aegilops tauschii Transcriptome Investigation Revealed Nine Novel miRNAs Involved in Stress Response

Volume: 15   Issue: 5
Pp: 455-462
Behnam Bakhshi* and Ehsan Mohseni Fard
DOI: 10.2174/1574893614666191017151708

A Review of Pathway Databases and Related Methods Analysis

Volume: 15   Issue: 5
Pp: 379-395
Ali Ghulam, Xiujuan Lei*, Min Guo and Chen Bian
DOI: 10.2174/1574893614666191018162505

ZFARED: A Database of the Antioxidant Response Elements in zebrafish

Volume: 15   Issue: 5
Pp: 415-419
Azhwar Raghunath*, Raju Nagarajan and Ekambaram Perumal*
DOI: 10.2174/1574893614666191018172213

APP Medical Diagnostic Check-Up Consultation System Based on Speech Recognition

Volume: 15   Issue: 5
Pp: 408-414
Zhi Li, Yusen Wang, Shiwen Tai, Jingquan Wang, Yusong Huang, Wu Jiang and Hao Zhang*
DOI: 10.2174/1574893614666191105161335

Genetic Algorithm-based Feature Selection Approach for Enhancing the Effectiveness of Similarity Searching in Ligand-based Virtual Screening

Volume: 15   Issue: 5
Pp: 431-444
Fouaz Berrhail* and Hacene Belhadef
DOI: 10.2174/1574893614666191119123935

Hardware Performance Evaluation of de novo Transcriptome Assembly Software in Amazon Elastic Compute Cloud

Volume: 15   Issue: 5
Pp: 420-430
Fernando Mora-Márquez, José Luis Vázquez-Poletti, Víctor Chano, Carmen Collada, Álvaro Soto and Unai López de Heredia*
DOI: 10.2174/1574893615666191219095817

Screening and Analysis of Hypolipidemic Components from Shuangdan Capsule based on Pancreatic Lipase

Volume: 15   Issue: 5
Pp: 478-492
YJ Qi*, HN Lu, YM Zhao, Z Wang, YJ Ji, NZ Jin and ZR Ma
DOI: 10.2174/1574893615666200106113910

A Sequence-Segment Neighbor Encoding Schema for Protein Hotspot Residue Prediction

Volume: 15   Issue: 5
Pp: 445-454
Peng Chen, Tong Shen, Youzhi Zhang* and Bing Wang*
DOI: 10.2174/1574893615666200106115421

Bioinformatics Analysis of the Rhizosphere Microbiota of Dangshan Su Pear in Different Soil Types

Volume: 15   Issue: 5
Pp: 503-514
Xiaojing Ma, Sambhaji Balaso Thakar, Huimin Zhang, Zequan Yu, Li Meng and Junyang Yue*
DOI: 10.2174/1574893615666200129104523

Predicting Thermophilic Proteins by Machine Learning

Volume: 15   Issue: 5
Pp: 493-502
Xian-Fang Wang*, Peng Gao, Yi-Feng Liu, Hong-Fei Li and Fan Lu
DOI: 10.2174/1574893615666200207094357

Predicting Protein Phosphorylation Sites Based on Deep Learning

Volume: 15   Issue: 4
Pp: 300-308
Haixia Long*, Zhao Sun, Manzhi Li, Hai Yan Fu and Ming Cai Lin*
DOI: 10.2174/1574893614666190902154332

A Machine Learning-based Diagnosis of Thyroid Cancer Using Thyroid Nodules Ultrasound Images

Volume: 15   Issue: 4
Pp: 349-358
Xuesi Ma, Baohang Xi, Yi Zhang, Lijuan Zhu, Xin Sui*, Geng Tian and Jialiang Yang*
DOI: 10.2174/1574893614666191017091959

SimExact – An Efficient Method to Compute Function Similarity Between Proteins Using Gene Ontology

Volume: 15   Issue: 4
Pp: 318-327
Najmul Ikram*, Muhammad Abdul Qadir and Muhammad Tanvir Afzal
DOI: 10.2174/1574893614666191017092842

Application of a Deep Matrix Factorization Model on Integrated Gene Expression Data

Volume: 15   Issue: 4
Pp: 359-367
Yong-Jing Hao, Mi-Xiao Hou, Ying-Lian Gao, Jin-Xing Liu* and Xiang-Zhen Kong
DOI: 10.2174/1574893614666191017094331

Finding Community of Brain Networks Based on Neighbor Index and DPSO with Dynamic Crossover

Volume: 15   Issue: 4
Pp: 287-299
Jie Zhang, Junhong Feng* and Fang-Xiang Wu*
DOI: 10.2174/1574893614666191017100657

Analysis and Comparison of RNA Pseudouridine Site Prediction Tools

Volume: 15   Issue: 4
Pp: 279-286
Wei Chen* and Kewei Liu
DOI: 10.2174/1574893614666191018171521

ConvsPPIS: Identifying Protein-protein Interaction Sites by an Ensemble Convolutional Neural Network with Feature Graph

Volume: 15   Issue: 4
Pp: 368-378
Huaixu Zhu, Xiuquan Du* and Yu Yao
DOI: 10.2174/1574893614666191105155713

A Novel Integrative Approach for Non-coding RNA Classification Based on Deep Learning

Volume: 15   Issue: 4
Pp: 338-348
Abdelbasset Boukelia*, Anouar Boucheham, Meriem Belguidoum, Mohamed Batouche, Farida Zehraoui and Fariza Tahi
DOI: 10.2174/1574893614666191105160633

Identification of Novel Key Targets and Candidate Drugs in Oral Squamous Cell Carcinoma open access plus

Volume: 15   Issue: 4
Pp: 328-337
Juan Liu, Xinjie Lian, Feng Liu, Xueling Yan, Chunyan Cheng, Lijia Cheng, Xiaolin Sun* and Zheng Shi*
DOI: 10.2174/1574893614666191127101836

A Sequential Ensemble Model for Communicable Disease Forecasting

Volume: 15   Issue: 4
Pp: 309-317
Nashreen Sultana*, Nonita Sharma, Krishna Pal Sharma and Shobhit Verma
DOI: 10.2174/1574893614666191202153824

Relevance of Molecular Docking Studies in Drug Designing

Volume: 15   Issue: 4
Pp: 270-278
Ritu Jakhar, Mehak Dangi, Alka Khichi and Anil Kumar Chhillar*
DOI: 10.2174/1574893615666191219094216

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Volume: 15   Issue: 4
Pp: 269-269
Bing Niu
DOI: 10.2174/157489361504200406092656

Elastic Net Regularized Softmax Regression Methods for Multi-subtype Classification in Cancer

Volume: 15   Issue: 3
Pp: 212-224
Lin Zhang*, Yanling He, Haiting Song, Xuesong Wang, Nannan Lu, Lei Sun and Hui Liu*
DOI: 10.2174/1574893613666181112141724

Sequence-based Structural B-cell Epitope Prediction by Using Two Layer SVM Model and Association Rule Features

Volume: 15   Issue: 3
Pp: 246-252
Jehn-Hwa Kuo, Chi-Chang Chang*, Chi-Wei Chen, Heng-Hao Liang, Chih-Yen Chang and Yen-Wei Chu*
DOI: 10.2174/1574893614666181123155831

HSEAT: A Tool for Plant Heat Shock Element Analysis, Motif Identification and Analysis

Volume: 15   Issue: 3
Pp: 196-203
Sarah Rizwan Qazi, Noor ul Haq, Shakeel Ahmad and Samina N. Shakeel*
DOI: 10.2174/1574893614666190102151956

Research on Gastric Cancer’s Drug-resistant Gene Regulatory Network Model

Volume: 15   Issue: 3
Pp: 225-234
Zhi Li, Tianyue Zhang, Haojie Lei, Liyan Wei, Yuanning Liu, Yadi Shi, Shuyi Li, Bowen Shen, Hao Guo, Zhangqian Chen, Xiaorong Yi and Hao Zhang*
DOI: 10.2174/1574893614666190722102557

Leukocyte Image Segmentation Based on Adaptive Histogram Thresholding and Contour Detection

Volume: 15   Issue: 3
Pp: 187-195
Xiaogen Zhou, Zuoyong Li, Huosheng Xie*, Ting Feng, Yan Lu, Chuansheng Wang and Rongyan Chen
DOI: 10.2174/1574893614666190723115832

MD-LBP: An Efficient Computational Model for Protein Subcellular Localization from HeLa Cell Lines Using SVM

Volume: 15   Issue: 3
Pp: 204-211
Muhammad Tahir* and Adnan Idris
DOI: 10.2174/1574893614666190723120716

Current State of the Art for Survival Prediction in Cancer Using Data Mining Techniques

Volume: 15   Issue: 3
Pp: 174-186
M.N. Doja, Ishleen Kaur* and Tanvir Ahmad
DOI: 10.2174/1574893614666190902152142

Citrullination Site Prediction by Incorporating Sequence Coupled Effects into PseAAC and Resolving Data Imbalance Issue

Volume: 15   Issue: 3
Pp: 235-245
Md. Al Mehedi Hasan, Md Khaled Ben Islam, Julia Rahman* and Shamim Ahmad
DOI: 10.2174/1574893614666191202152328

Stability Analysis at Key Positions of EGFR Related to Non-small Cell Lung Cancer

Volume: 15   Issue: 3
Pp: 260-267
Avirup Ghosh* and Hong Yan
DOI: 10.2174/1574893614666191212112026

Mutation Mechanisms of Breast Cancer among the Female Population in China

Volume: 15   Issue: 3
Pp: 253-259
Asmaa Amer, Ahmed Nagah, Tianhai Tian* and Xinan Zhang*
DOI: 10.2174/1574893615666191220141548

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Volume: 15   Issue: 3
Pp: 173-173
Pu-Feng Du
DOI: 10.2174/157489361503200303121210

A Comparative Study to Explore the Effect of Different Compounds in Immune Proteins of Human Beings Against Tuberculosis: An In-silico Approach

Volume: 15   Issue: 2
Pp: 155-164
Manish Kumar Tripathi, Mohammad Yasir, Pushpendra Singh and Rahul Shrivastava*
DOI: 10.2174/1574893614666190226153553

Prediction of RNA Secondary Structure Using Quantum-inspired Genetic Algorithms

Volume: 15   Issue: 2
Pp: 135-143
Sha Shi, Xin-Li Zhang, Le Yang, Wei Du, Xian-Li Zhao* and Yun-Jiang Wang*
DOI: 10.2174/1574893614666190916154103

Integrated In-silico Analysis to Study the Role of microRNAs in the Detection of Chronic Kidney Diseases

Volume: 15   Issue: 2
Pp: 144-154
Amina Khan, Andleeb Zahra, Sana Mumtaz, M. Qaiser Fatmi* and Muhammad J. Khan*
DOI: 10.2174/1574893614666190923115032

Elucidating the Functional Role of Predicted miRNAs in Post- Transcriptional Gene Regulation Along with Symbiosis in Medicago truncatula

Volume: 15   Issue: 2
Pp: 108-120
Moumita Roy Chowdhury, Jolly Basak* and Ranjit Prasad Bahadur*
DOI: 10.2174/1574893614666191003114202

Protein Secondary Structure Prediction: A Review of Progress and Directions open access plus

Volume: 15   Issue: 2
Pp: 90-107
Tomasz Smolarczyk, Irena Roterman-Konieczna and Katarzyna Stapor*
DOI: 10.2174/1574893614666191017104639

Comparative Transcriptome Profiling of Disruptive Technology, Single- Molecule Direct RNA Sequencing

Volume: 15   Issue: 2
Pp: 165-172
Chaithra Pradeep, Dharam Nandan, Arya A. Das and Dinesh Velayutham*
DOI: 10.2174/1574893614666191017154427

A Study on Host Tropism Determinants of Influenza Virus Using Machine Learning

Volume: 15   Issue: 2
Pp: 121-134
Eunmi Kwon, Myeongji Cho, Hayeon Kim and Hyeon S. Son*
DOI: 10.2174/1574893614666191104160927

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Volume: 15   Issue: 2
Pp: 89-89
Song Xiaofeng
DOI: 10.2174/157489361502200225121719

Predicting Drug-target Interactions via FM-DNN Learning

Volume: 15   Issue: 1
Pp: 68-76
Jihong Wang, Hao Wang, Xiaodan Wang and Huiyou Chang*
DOI: 10.2174/1574893614666190227160538

The Expression Profiles of lncRNAs and Their Regulatory Network During Smek1/2 Knockout Mouse Neural Stem Cells Differentiation

Volume: 15   Issue: 1
Pp: 77-88
Qichang Yang, Jing Wu, Jian Zhao, Tianyi Xu, Ping Han* and Xiaofeng Song*
DOI: 10.2174/1574893614666190308160507