Endocrine, Metabolic & Immune Disorders - Drug Targets

Focus on Receptors for Coronaviruses with Special Reference to Angiotensin- Converting Enzyme 2 as a Potential Drug Target - A Perspective open access plus

Volume:20   Issue:6
Pp: 807-811
Thea Magrone, Manrico Magrone and Emilio Jirillo*
DOI: 10.2174/1871530320666200427112902

Predictors for Fibrosis Regression in Chronic HCV Patients after the Treatment with DAAS: Results of a Real-world Cohort Study open access plus

Volume:20   Issue:1
Pp: 104-111
Hanan Soliman, Dina Ziada, Marwa Salama, Manal Hamisa, Rehab Badawi, Nehad Hawash, Amal Selim and Sherief Abd-Elsalam*
DOI: 10.2174/1871530319666190826150344

Peripheral Immunosenescence and Central Neuroinflammation: A Dangerous Liaison - A Dietary Approach

Volume:20   Issue:9
Pp: 1391-1411
Thea Magrone*, Manrico Magrone, Matteo A. Russo and Emilio Jirillo
DOI: 10.2174/1871530320666200406123734

Our Little Friends with Big Roles: Alterations of the Gut Microbiota in Thyroid Disorders

Volume:20   Issue:3
Pp: 344-350
Hanieh-Sadat Ejtahed, Pooneh Angoorani, Ahmad-Reza Soroush, Seyed-Davar Siadat, Nooshin Shirzad, Shirin Hasani-Ranjbar* and Bagher Larijani
DOI: 10.2174/1871530319666190930110605

Anti-Cancerous Effect of Rutin Against HPV-C33A Cervical Cancer Cells via G0/G1 Cell Cycle Arrest and Apoptotic Induction

Volume:20   Issue:3
Pp: 409-418
Fahad Khan, Pratibha Pandey*, Tarun K. Upadhyay, Asif Jafri, Niraj K. Jha, Rashmi Mishra and Vineeta Singh
DOI: 10.2174/1871530319666190806122257

Molecular and Immunological Mechanisms Underlying the Various Pharmacological Properties of the Potent Bioflavonoid, Rutin

Volume:20   Issue:10
Pp: 1590-1596
David O.C. Yong, Sanggetha R. Saker, Dinesh K. Chellappan*, Thiagarajan Madheswaran, Jithendra Panneerselvam, Hira Choudhury, Manisha Pandey, Yik L. Chan, Trudi Collet, Gaurav Gupta, Brian G. Oliver, Peter Wark, Nicole Hansbro, Alan Hsu, Philip M. Hansbro, Kamal Dua* and Farrukh Zeeshan
DOI: 10.2174/1871530320666200503053846

The Preventive Effect of IL-1beta Antagonist on Diabetic Peripheral Neuropathy

Volume:20   Issue:5
Pp: 753-759
Zheng Hangping , Han Ling, Ji Lijin, Zhao Wenting, Liu Xiaoxia, Zhang Qi, Zhu Xiaoming, Li Qingchun, Li Yiming, Xiong Qian, Hu Ji, Lu Bin* and Zhang Shuo*
DOI: 10.2174/1871530319666191022114139

Immune-Inflammation in Atherosclerosis: A New Twist in an Old Tale

Volume:20   Issue:4
Pp: 525-545
Atefe Ghamar Talepoor, Hamed Fouladseresht, Shahdad Khosropanah and Mehrnoosh Doroudchi*
DOI: 10.2174/1871530319666191016095725

Quality of Life in Individuals with Diabetic Foot Syndrome

Volume:20   Issue:9
Pp: 1365-1372
Emmanuel Navarro-Flores and Omar Cauli*
DOI: 10.2174/1871530320666200128154036

Diagnostic Approach to the Patients with Suspected Primary Immunodeficiency

Volume:20   Issue:2
Pp: 157-171
Marzieh Tavakol, Mahnaz Jamee, Gholamreza Azizi*, Homa Sadri, Yasser Bagheri, Majid Zaki-Dizaji, Fatemeh Sadat Mahdavi, Farhad Jadidi-Niaragh, Sanaz Tajfirooz, Ali N. Kamali, Fatemeh Aghamahdi, Shahab Noorian, Habibeh Taghavi Kojidi, Mehdi Mosavian, Rahman Matani, Elahe Dolatshahi, Kumars Porrostami, Nasrin Elahimehr, Marzie Fatemi-Abhari, Laleh Sharifi, Reza Arjmand, Sabahat Haghi, Hamed Zainaldain, Reza Yazdani, Mohammadreza Shaghaghi, Hassan Abolhassani and Asghar Aghamohammadi
DOI: 10.2174/1871530319666190828125316

LncRNA, Important Player in Bone Development and Disease

Volume:20   Issue:1
Pp: 50-66
Dijie Li, Chaofei Yang, Chong Yin, Fan Zhao, Zhihao Chen, Ye Tian, Kai Dang, Shanfeng Jiang, Wenjuan Zhang, Ge Zhang and Airong Qian*
DOI: 10.2174/1871530319666190904161707

Curcumin Suppresses Epithelial Growth Factor Receptor (EGFR) and Proliferative Protein (Ki 67) in Acute Lung Injury and Lung Fibrosis In vitro and In vivo

Volume:20   Issue:4
Pp: 558-563
Sadiya Bi Shaikh, Ashwini Prabhu and Yashodhar Prabhakar Bhandary*
DOI: 10.2174/1871530319666190823160230

Differential Expression of Resistant and Efflux Pump Genes in MDR-TB Isolates open access plus

Volume:20   Issue:2
Pp: 271-287
Manaf AlMatar*, Işıl Var, Begüm Kayar and Fatih Köksal
DOI: 10.2174/1871530319666191009153834

The Association between HbA1c Levels, Olfactory Memory and Cognition in Normal, Pre-Diabetic and Diabetic Persons

Volume:20   Issue:2
Pp: 198-212
Burak Yulug*, Ozlem Saatci, Aysun Işıklar, Lutfu Hanoglu, Ulkan Kilic, Mehmet Ozansoy, Seyda Cankaya, Baris Cankaya and Ertugrul Kilic
DOI: 10.2174/1871530319666190614121738

The Effect of Vitamin D Supplementation on Clinical Outcomes of Asthmatic Children with Vitamin D Insufficiency

Volume:20   Issue:1
Pp: 149-155
Rasoul N. Kalmarzi, Sivan Ahmadi, Ramesh Rahehagh, Asadollah Fathallahpour, Behzad Khalafi, Hajar Kashefi, Daem Roshani, Rama N. Zaryan, Shilan Mohamadi and Wesam Kooti*
DOI: 10.2174/1871530319666190426161809

Are Oxidative Stress and Inflammation Mediators of Bone Loss Due to Estrogen Deficiency? A Review of Current Evidence open access plus

Volume:20   Issue:9
Pp: 1478-1487
Nur-Vaizura Mohamad, Soelaiman Ima-Nirwana and Kok-Yong Chin*
DOI: 10.2174/1871530320666200604160614

Impact of Heavy Metals on Host Cells: Special Focus on Nickel-Mediated Pathologies and Novel Interventional Approaches

Volume:20   Issue:7
Pp: 1041-1058
Thea Magrone*, Matteo A. Russo and Emilio Jirillo
DOI: 10.2174/1871530319666191129120253

Interleukin 1-beta is Linked to Chronic Low-Grade Inflammation and Cardiovascular Risk Factors in Overweight Adolescents

Volume:20   Issue:6
Pp: 887-894
Gisele A. Amaral, Josilene D. Alves, Adenilda C. Honorio-França, Danny L. Fagundes, Gabriel Gomes Araujo, Nubia S. Lobato, Victor V. Lima and Fernanda R. Giachini*
DOI: 10.2174/1871530319666191116141159

Hepatocyte Growth Factor Attenuates the Development of TGF-β1- Induced EndMT through Down-regulating the Notch Signaling

Volume:20   Issue:5
Pp: 781-787
Ruiping Yang, Fan Yang, Yingchun Hu, Muhu Chen, Ying Liu, Jinpeng Li and Wu Zhong*
DOI: 10.2174/1871530319666191023141638

Mechanism Underlying the Formation of a Cluster of Metabolic Syndrome

Volume:20   Issue:4
Pp: 564-569
Svetlana Igorevna Kseneva*, Elena Valentinovna Borodulina, Vladimir Vasilievich Udut and Vladimir Petrovich Fisenko
DOI: 10.2174/1871530319666191007115214

The Association of Metabolic Syndrome and Psoriasis: A Systematic Review and Meta-Analysis of Observational Study

Volume:20   Issue:5
Pp: 703-717
Saumya Choudhary, Dibyabhaba Pradhan, Anamika Pandey, Mohd. Kamran Khan, Rohit Lall, V. Ramesh, Poonam Puri, Arun K. Jain* and George Thomas*
DOI: 10.2174/1871530319666191008170409

Key Relevance of Epigenetic Programming of Adiponectin Gene in Pathogenesis of Metabolic Disorders

Volume:20   Issue:4
Pp: 506-517
Kaiser Un Nisa and Mohammad Irshad Reza*
DOI: 10.2174/1871530319666190801142637

The “Scourge of the Renaissance”. A Short Review About Treponema pallidum infection

Volume:20   Issue:3
Pp: 335-343
Luigi Santacroce*, Lucrezia Bottalico*, Skender Topi, Francesca Castellaneta and Ioannis A. Charitos
DOI: 10.2174/1871530319666191009144217

The Role of Chemokines in Alzheimer's Disease

Volume:20   Issue:9
Pp: 1383-1390
Adrian Jorda, Juan Campos-Campos, Antonio Iradi, Martin Aldasoro, Constanza Aldasoro, Jose M. Vila and Soraya L. Valles*
DOI: 10.2174/1871530320666200131110744

Proteomics Screening of Differentially Expressed Cytokines in Tears of Patients with Graves’ Ophthalmopathy

Volume:20   Issue:1
Pp: 87-95
Rong-Hua Song, Bin Wang, Qiu-Ming Yao, Qian Li, Xi Jia and Jin-An Zhang*
DOI: 10.2174/1871530319666190618142215