ISSN (Print): 1570-1808 ISSN (Online): 1875-628X Volume 17, 12 Issues, 2020
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ISSN (Print): 1570-1808 ISSN (Online): 1875-628X
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Has contributed: CETP Inhibitory Activity of Chlorobenzyl Benzamides: QPLD Docking, Pharmacophore Mapping and Synthesis.
A Novel Combinational Nanodrug Delivery System Induces Synergistic Inhibition of Lung Adenocarcinoma Cells In vitro
Volume: 18 Issue: 1 Pp: 104-110 Mingliang Fan and Jiping Li* DOI: 10.2174/1570180817999200719152426
Unveiling the Anti-tubercular Properties of Biscoumarins, through Biological Evaluation and Docking Studies
Volume: 18 Issue: 1 Pp: 57-66 Poornima Acharya, M.M.V. Ramana*, Manish Upadhyay and Ganesh Pavale DOI: 10.2174/1570180817999200724173656
Preliminary Identification of Hamamelitannin and Rosmarinic Acid as COVID-19 Inhibitors Based on Molecular Docking
Volume: 18 Issue: 1 Pp: 67-75 Kaushik Sarkar and Rajesh Kumar Das* DOI: 10.2174/1570180817999200802032126
In Silico Based Structural and Fingerprint Analysis of Structurally Diverse AT1 inhibitors
Volume: 18 Issue: 1 Pp: 93-103 Narayana Subbiah Hari Narayana Moorthy* DOI: 10.2174/1570180817999200818155601
Design, Synthesis and Biological Evaluation of 3-(2-(benzo[d]thiazol-2- ylthio)acetamido)benzoic Acid Derivatives as Inhibitors of Protein Tyrosine Phosphatase 1B
Volume: 18 Issue: 1 Pp: 46-56 Monika Rakse*, Chandrabose Karthikeyan, Narayana Subbiah Hari Narayana Moorthy and Ram Kishore Agrawal DOI: 10.2174/1570180817999200819122350
Triazolylthioacetamides Confer Inhibitory Efficacy against Metallo-β- Lactamase IMP-1
Volume: 18 Issue: 1 Pp: 76-84 Yue-Juan Zhang, Le Zhai, Yi Wan and Ke-Wu Yang* DOI: 10.2174/1570180817999200831094019
Molecular Docking Analysis of Flavonoid Compounds with Matrix Metalloproteinase- 8 for the Identification of Potential Effective Inhibitors
Volume: 18 Issue: 1 Pp: 16-45 Amir Taherkhani, Athena Orangi, Shirin Moradkhani and Zahra Khamverdi* DOI: 10.2174/1570180817999200831094703
Synthesis of PF-543 Derivatives Using Simple Synthetic Methods and Their Biological Effect Analysis for the Development of Anticolorectal Cancer Agents
Volume: 18 Issue: 1 Pp: 85-92 Jitendra Shrestha, Joo-Youn Lee, Eun-Young Park* and Dong Jae Baek* DOI: 10.2174/1570180817999200908093524
Synthesis of New Bis-pyrazolines Endowed with Potent Antifungal Activity against Candida albicans and Aspergillus niger
Volume: 18 Issue: 1 Pp: 3-15 Belgin Sever, Mehlika Dilek Altintop* and Ahmet Özdemir DOI: 10.2174/1570180817999201008155247
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Volume: 18 Issue: 1 Pp: 1-1 Mehlika Dilek Altintop DOI: 10.2174/157018081801201217094130
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Volume: 18 Issue: 1 Pp: 2-2 Kamil Kuca DOI: 10.2174/157018081801201217095239
Current scenario of COVID-19
Volume: 18 Issue: Pp: 1-13 Priyank Purohit*, Ravi Kumar Mittal and Kanika Bhatt DOI: 10.2174/1570180818999201224115202
A Study on Leukemic and Non-small Cell Lung Cancer Efficacy of Novel Isoxazoles Synthesized by Microwave Irradiation
Volume: 18 Issue: Pp: 1-11 Mayank Pandya and Khushal Kapadiya* DOI: 10.2174/1570180818999201224115641
New Viral Infection COVID-19: Current Status, Challenges and Possible Treatments
Volume: 18 Issue: Pp: 1-19 Vipan Kumar, Amruta Suryan, Jyoti Singh*, Sandeep Kumar, Pradeep Kamboj and Aakash Deep DOI: 10.2174/1570180818999201224120233
Exploring Nature’s Treasure to Inhibit β-Barrel Assembly Machinery of Antibiotic Resistant Bacteria: An In-Silico Approach
Volume: 18 Issue: Pp: 1-14 Shalja Verma and Anand Kumar Pandey* DOI: 10.2174/1570180818999201224121342
Synthesis and Enzymological Characterization of Some 2- (Substitutedphenylamino)quinazolin-4(3H)-one Derivatives as Potent αGlucosidase Inhibitors In vitro
Volume: 18 Issue: Pp: 1-13 Emre Kadir Ayan, Zeynep Soyer* and Şirin Uysal DOI: 10.2174/1570180818999201224121929
Diagnostic, Prognostic and Therapeutic Potential of Heat Shock Proteins in Schistosomiasis and Bladder Cancer: A Review
Volume: 18 Issue: Pp: 1-21 Ndibonani Kebonang Qokoyi, Priscilla Masamba, Geraldene Munsamy and Abidemi Paul Kappo* DOI: 10.2174/1570180818999201228205317
Fragment-Based Drug Design of Antitumoral Molecules Polo-like kinase 1 inhibitors: in-silico approach
Volume: 18 Issue: Pp: 1-18 Ayoub Attoui, Widad Sobhi, Nour El Houda Hammoudi and Yacine Benguerba* DOI: 10.2174/1570180818999201230195526
Pharmacophore-based screening for identification of Human Acyl-CoA cholesterol acyltransferase inhibitors: An in-silico study
Volume: 18 Issue: Pp: 1-14 Ankit Dhaundiyal*, Puja Kumari and Shasta Kalra DOI: 10.2174/1570180818999201231200643
A QSAR study of peptidyl vinyl sulfone cysteine protease inhibitors using Topomer CoMFA and Molecular Docking
Volume: 18 Issue: Pp: 1-1 WU Lu-Yang, MA Yang-Min*, LEI Shan, WANG Tian-Hao and FENG Yi DOI: 10.2174/1570180818666210114115030
Computational Bioactivity Analysis and Bioisosteric Investigation of the Approved Breast Cancer Drugs Proposed New Design Drug Compounds: Increased Bioactivity Coming with Silicon and Boron
Volume: 18 Issue: Pp: 1-1 Esma Eryilmaz Dogan* DOI: 10.2174/1570180818666210114115415
Synthesis of Chrysin, Quercetin and Naringin Nitroderivatives: Antiproliferative, Anti-Inflammatory and Antioxidant Activity
Volume: 18 Issue: Pp: 1-1 Rosario Tavera-Hernández, Manuel Jiménez-Estrada*, Jesús J. Alvarado-Sansininea, Antonio Nieto-Camacho, Hugo López-Muñoz, Luis Sánchez-Sánchez and María L. Escobar DOI: 10.2174/1570180818666210122162313
Mode Action Prediction of Butein as Antibacterial Oral Pathogen against Enterococcus faecalis ATCC 29212 and as Inhibitor of MurA Enzyme: In Vitro and In Silico Study
Volume: 18 Issue: Pp: 1-1 Mieke Hemiawati Satari*, Ameta Primasari, Hendra Dian Adhita Dharsono, Eti Apriyanti, Maria Matoetina Suprijono, Yetty Herdiyati and Dikdik Kurnia* DOI: 10.2174/1570180818666210122163009
In Silico ADMET and Docking Studies of Thiazolidinedione-acetic-acid Hybrids as Antidiabetics with Cardioprotection
Volume: 17 Issue: 12 Pp: 1475-1484 Deepanwita Maji, Subir Samanta and Vaishali M. Patil* DOI: 10.2174/1570180817999200618103328
Synthesis and Evaluation of Substituted Aryl Thiazoles With Antioxidant Potential as Gastro-sparing Anti-inflammatory Agents
Volume: 17 Issue: 12 Pp: 1566-1578 Akhil Bansal, Alka Bali* and Ajitesh Balaini DOI: 10.2174/1570180817999200706005247
3,4,5-Trisubstituted-1,2,4-triazole Derivatives as Antiproliferative Agents: Synthesis, In vitro Evaluation and Molecular Modelling
Volume: 17 Issue: 12 Pp: 1502-1515 Leyla Yurttaş*, Asaf Evrim Evren, Aslıhan Kubilay, Halide Edip Temel and Gülşen Akalın Çiftçi DOI: 10.2174/1570180817999200712190831
The Potency of Catechin from Gambir (Uncaria gambir Roxb.) as a Natural Inhibitor of MurA (1UAE) Enzyme: In vitro and In silico studies
Volume: 17 Issue: 12 Pp: 1531-1537 Bella Riyana, Desi Harneti Putri Huspa, Mieke Hemiawati Satari and Dikdik Kurnia* DOI: 10.2174/1570180817999200714104737
Synthesis and In silico Studies of Quinazolinone Derivatives as PARP-1 Inhibitors
Volume: 17 Issue: 12 Pp: 1552-1565 Sonia Verma, Akashdeep Singh Pathania, Somesh Baranwal and Pradeep Kumar* DOI: 10.2174/1570180817999200719152959
Virtual Compound Screening and Molecular Dynamics to Identify New Inhibitors for Human Glutathione Reductase
Volume: 17 Issue: 12 Pp: 1465-1474 Mohsen Sargolzaei* DOI: 10.2174/1570180817999200724174003
In Silico Anticancer Evaluation, Molecular Docking and Pharmacophore Modeling of Flavonoids against Various Cancer Targets
Volume: 17 Issue: 12 Pp: 1485-1501 Jainey Puthenveettil James*, Pankaj Kumar*, Abhishek Kumar, Katte Ishwar Bhat and Chakrakodi Shashidhara Shastry DOI: 10.2174/1570180817999200730164222
Microwave Assisted, Antimicrobial Activity and Molecular Modeling of Some Synthesized Newly Pyrimidine Derivatives Using 1, 4- diazabicyclo[2.2.2]octane as a Catalyst
Volume: 17 Issue: 12 Pp: 1538-1551 Nadia Ali Ahmed Elkanzi and Rania Badaway Bakr* DOI: 10.2174/1570180817999200802033351
Novel Coronavirus 2019 Outbreak: A Global Epidemic
Volume: 17 Issue: 12 Pp: 1458-1464 Sweta Kamboj*, Rohit Kamboj, Shikha Kamboj, Kumar Guarve and Rohit Dutt DOI: 10.2174/1570180817999200802033916
Identification of Putative “Multifunctional Drug” Against Anthrax Toxins via Integrative Computational Approach
Volume: 17 Issue: 12 Pp: 1516-1530 Nousheen Bibi*, Sehraiz Razzaq, Faisal Nouroz, Farhat Amin, Ambreen Shahnaz and Mohammad Amjad Kamal DOI: 10.2174/1570180817999200818175544
Development of Schiff bases from Amikacin: Synthesis, Antibacterial, Anti-urease Activities and Molecular Docking Studies
Volume: 17 Issue: 12 Pp: 1579-1588 Shabana Anwar*, Mohsin Abbas Khan*, Irshad Ahmed, Irfan Pervaiz and Hamid Saeed Shah DOI: 10.2174/1570180817999200921112605
Volume: 17 Issue: 12 Pp: 1457-1457 Yiyun Cheng DOI: 10.2174/157018081712201023090521
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Volume: 17 Issue: 12 Pp: 1589-1590 DOI: 10.2174/157018081712201023090555
Novel 2-(5-Aryl)thiophen-2-yl)benzimidazoles; Design, Synthesis and In vitro Evaluation Against Cercarial Phase of Schistosoma mansoni
Volume: 17 Issue: 11 Pp: 1432-1438 Serry Atta El Bialy, Basem Mansour*, Waleed Abdelhakeem Bayoumi, Amira Taman and Hassan Mohammed Eissa DOI: 10.2174/1570180817999200523181211
Synthesis, Characterization and Antimicrobial Activity of Some Novel 1- substituted Benzimidazole Derivatives
Volume: 17 Issue: 11 Pp: 1372-1379 Erkut Isik, Demet Astley, Seda Yuksekdanaci* and Ihsan Yasa DOI: 10.2174/1570180817999200531164230
Comparative Proteome Analysis of Mycobacterium Tuberculosis Strains - H37Ra, H37Rv, CCDC5180, and CAS/NITR204: A Step Forward to Identify Novel Drug Targets
Volume: 17 Issue: 11 Pp: 1422-1431 Shradheya R.R. Gupta, Ekta Gupta, Avnam Ohri, Sandeep Kumar Shrivastava, Sumita Kachhwaha, Vinay Sharma, Rupesh Kumar Mishra and Ravi Ranjan Kumar Niraj* DOI: 10.2174/1570180817999200531165148
Computational Analysis of Dynamical Fluctuations of Oncoprotein E7 (HPV 16) for the Hot Spot Residue Identification Using Elastic Network Model
Volume: 17 Issue: 11 Pp: 1393-1400 Rabbiah Malik*, Sahar Fazal and Mohammad Amjad Kamal DOI: 10.2174/1570180817999200606225735
Design, Synthesis and Biological Evaluation: 5-amino-1H-pyrazole-1- carbonyl derivatives as FGFR Inhibitors
Volume: 17 Issue: 11 Pp: 1330-1341 Yan Zhang and Niefang Yu* DOI: 10.2174/1570180817999200608140628
Synthesis and Evaluation of Dapagliflozin Ester Prodrugs with Improved Hygroscopicity and Thermal Stability
Volume: 17 Issue: 11 Pp: 1409-1421 Si Young Sung, Yu Na Chae, Dae Young Lee, Kyeong Min Kim, Eun Jung Kim, Ji Hye Han, Wook Kim and Sung-Hwa Yoon* DOI: 10.2174/1570180817999200618162949
Design, Synthesis, In vitro and In silico Evaluation of New Hydrazonebased Antitumor Agents as Potent Akt Inhibitors
Volume: 17 Issue: 11 Pp: 1380-1392 Emine Merve Güngör, Mehlika Dilek Altıntop*, Belgin Sever and Gülşen Akalın Çiftçi DOI: 10.2174/1570180817999200618163507
Design, Synthesis, Docking and Computational Pharmacokinetic Profiling of New Pyrazolinyl Thiazolinone Biheterocycles as Potent Antimicrobial Agents
Volume: 17 Issue: 11 Pp: 1342-1354 Vinutha Vittala Salian, Badiadka Narayana*, Balladka Kunhanna Sarojini, Sharath Chandra Kodandoor and Anupam Glorious Lobo DOI: 10.2174/1570180817999200623115049
Evaluation of Kaempferol as AKT Dependent mTOR Regulator via Targeting FKBP-12 in Hepatocellular Carcinoma: An In silico Approach
Volume: 17 Issue: 11 Pp: 1401-1408 Pooja Siniprasad, Bhagyalakshmi Nair, Vaisali Balasubramaniam, Prashanth Sadanandan, Puliyapally Krishnan Namboori* and Lekshmi Reghu Nath* DOI: 10.2174/1570180817999200623115703
QSAR Studies of Sulfonamide Hydroxamates Derivatives as MMP-2 Inhibitors Topomer CoMFA and Molecular Docking
Volume: 17 Issue: 11 Pp: 1364-1371 Jian-Bo Tong*, Feng Yi, Ding Luo and Tian-Hao Wang DOI: 10.2174/1570180817999200630124920
Evaluating Phenyl Propanoids Isolated from Citrus medica as Potential Inhibitors for Mitotic kinesin Eg5
Volume: 17 Issue: 11 Pp: 1355-1363 Himesh Makala, Venkatasubramanian Ulaganathan*, Aravind Sivasubramanian, Narendran Rajendran and Shankar Subramanian DOI: 10.2174/1570180817999200630125449
High Anti-cancer Activity, Low Animal Toxicity, and Structure Activity Relationships of Curcumin Analogs
Volume: 17 Issue: 11 Pp: 1439-1455 Sen-Chuan Song, Yu-Liang Mai, Hua-Hong Shi, Bing Liao* and Fei Wang* DOI: 10.2174/2352096513999200714103641
Meet Our Associate Editor promotion: free to download
Volume: 17 Issue: 11 Pp: 1329-1329 György Keglevich DOI: 10.2174/157018081711200924121208
Synthesis, Molecular Docking and α-Glucosidase Inhibitory Activity Study of 2,4,6-triaryl Pyrimidine Derivatives
Volume: 17 Issue: 10 Pp: 1216-1226 Mohammed Hussen Bule , Roghaieh Esfandyari, Tadesse Bekele Tafesse, Mohsen Amini*, Mohammad Ali Faramarzi and Mohammad Abdollahi DOI: 10.2174/1570180817666200103130536
Preliminary Analysis of Anti-proliferative, Apoptotic, and Anti-migratory Effects llw-3-6 in Skov-3 Ovarian Cystadenocarcinoma Cell Line
Volume: 17 Issue: 10 Pp: 1319-1324 Rosalind Gregory-Bass and Leyte L. Winfield* DOI: 10.2174/1570180817666200129142949
Molecular Docking of 4-ethoxychalcones on Oxidoreductase/Pirin Inhibitors and Cytotoxic Evaluation on Breast/Skin Cancer Cell Lines
Volume: 17 Issue: 10 Pp: 1245-1260 Kishori Ramachandra Harshitha, Balladka Kunhanna Sarojini*, Badiadka Narayana, Anupam Glorious Lobo and Bhuvanesh Sukhlal Kalal DOI: 10.2174/1570180817666200129143803
Experimental Study of Therapeutic Efficacy of the Topical Preparation «Kourochitin» in Skin Allergy
Volume: 17 Issue: 10 Pp: 1237-1244 Anna Anatolievna Klimovich*, Olga Nikolaevna Styshova, Alexander Mikhailovich Popov, Tatiana Vladimirovna Moskvina*, Alexander Vasilevich Tsybulsky, Dmitry Albertovich Derunov and Valentin Aronovich Stonik DOI: 10.2174/1570180817666200316155643
Fingerprint-based 2D-QSAR Models for Predicting Bcl-2 Inhibitors Affinity
Volume: 17 Issue: 10 Pp: 1206-1215 Said Byadi, Hachim Mouhi Eddine, Karima Sadik, Črtomir Podlipnik and Aziz Aboulmouhajir* DOI: 10.2174/1570180817999200414155403
Novel Benzimidazole Derivatives: Cytotoxic and Apoptotic Properties on Lung Cancer Cell Line
Volume: 17 Issue: 10 Pp: 1227-1236 Leyla Yurttaş*, Gülşen Akalin Çiftçi, Mehmet Onur Aksoy and Şeref Demirayak DOI: 10.2174/1570180817999200513091613
Effect of Cabergoline on Cognitive Impairments in Transgenic Drosophila Model of Parkinson’s Disease
Volume: 17 Issue: 10 Pp: 1261-1269 Yasir Hasan Siddique*, Rahul, Mantasha Idrisi and Mohd. Shahid DOI: 10.2174/1570180817999200514100917
Molecular Insights into the Interaction of Ursolic Acid and Cucurbitacin from Colocynth with Therapeutic Targets of Mycobacterium tuberculosis
Volume: 17 Issue: 10 Pp: 1309-1318 Mohammad Ajmal Ali*, Mohammad Abul Farah*, Joongku Lee, Khalid M. Al-Anazi and Fahad M.A. Al-Hemaid DOI: 10.2174/1570180817999200514102750
Anti-inflammatory Augmentation Therapy in Obsessive-compulsive Disorder: A Review
Volume: 17 Issue: 10 Pp: 1198-1205 Hanie Ghasemi, Homa Nomani, Amirhossein Sahebkar* and Amir Hooshang Mohammadpour* DOI: 10.2174/1570180817999200520122910
Aminoalkylated Phenolic Chalcones: Investigation of Biological Effects on Acetylcholinesterase and Carbonic Anhydrase I and II as Potential Lead Enzyme Inhibitors
Volume: 17 Issue: 10 Pp: 1283-1292 Cem Yamali*, Halise Inci Gul*, Tahir Cakir, Yeliz Demir and Ilhami Gulcin DOI: 10.2174/1570180817999200520123510
Design, Synthesis and Biological Evaluation of Dimethyl Cardamonin (DMC) Derivatives as P-glycoprotein-mediated Multidrug Resistance Reversal Agents
Volume: 17 Issue: 10 Pp: 1270-1282 Ximeng Shi, Yuyu Zhao, Licheng Zhou, Huanhuan Yin, Jianwen Liu* and Lei Ma* DOI: 10.2174/1570180817999200531162015
Molecular Docking and QSAR Studies of Coumarin Derivatives as NMT Inhibitors: Simple Structural Features as Potential Modulators of Antifungal Activity
Volume: 17 Issue: 10 Pp: 1293-1308 Sapna Jain Dabade, Dheeraj Mandloi* and Amritlal Bajaj DOI: 10.2174/1570180817999200617105711
Drug Re-purposing from SARS-CoV Led the Identification of Potential Candidate Drug Target and Alternate Drug Molecules Against SARSCoV- 2 promotion: free to download
Volume: 17 Issue: 10 Pp: 1325-1327 PV Parvati Sai Arun*, Razak Hussain, Yusuf Akhter, Mandava Venkata Basaveswara Rao, Perugu Shyam and Sailu Yellaboina DOI: 10.2174/1570180817999200730190600
Volume: 17 Issue: 10 Pp: 1197-1197 Eng-Ang Ling DOI: 10.2174/157018081710200924092601
Effect of Steroidal Hormone Pregnenolone on Proliferation and Differentiation of MC3T3-E1 Osteoblast like Cells
Volume: 17 Issue: 9 Pp: 1139-1145 Serene Adnan Badran, Atia-tul-Wahab*, Sharmeen Fayyaz, Bushra Taj Muhammad and Muhammad Iqbal Choudhary* DOI: 10.2174/1570180817666200204110859
A Review on Robust Computational Approaches Based Identification and Authentication of Herbal Raw Drugs
Volume: 17 Issue: 9 Pp: 1066-1083 Preet Amol Singh, Neha Bajwa, Subh Naman and Ashish Baldi* DOI: 10.2174/1570180817666200304125520
Binding Mode Prediction and Identification of New Lead Compounds from Natural Products as 3-OST Enzyme Inhibitors
Volume: 17 Issue: 9 Pp: 1186-1196 Rui Sousa, Narayana Subbiah Hari Narayana Moorthy*, Pedro Alexandrino Fernandes, Maria Joao Ramos and Natércia Fernandes Brás DOI: 10.2174/1570180817666200313105944
In Vitro Characteristics of Glioma Cells Targeting by OX26-modified Liposomal Cisplatin
Volume: 17 Issue: 9 Pp: 1126-1138 Maryam Sadat Ashrafzadeh, Amir Heydarinasab*, Azim Akbarzadeh and Mehdi Ardjmand DOI: 10.2174/1570180817999200330165213
Indole Curcumin Reverses Multidrug Resistance by Reducing the Expression of ABCB1 and COX2 in Induced Multidrug Resistant Human Lung Cancer Cells
Volume: 17 Issue: 9 Pp: 1146-1154 Sankar Pajaniradje , Kumaravel Mohankumar, Rakesh Radhakrishnan , Shamim Akhtar Sufi, Srividya Subramanian , Parthiban Anaikutti, Surya Prakash Rao Hulluru and Rukkumani Rajagopalan * DOI: 10.2174/1570180817666200402124503
Synthesis and Biological Evaluation of Benzodioxol Derivatives as Cyclooxygenase Inhibitors
Volume: 17 Issue: 9 Pp: 1117-1125 Nidal Jaradat*, Mohammed Hawash and Murad Abualhasan DOI: 10.2174/1570180817999200420114402
Oleanolic Acid Derived from Plants: Synthesis and Pharmacological Properties of A-ring Modified Derivatives
Volume: 17 Issue: 9 Pp: 1084-1101 Tingjuan Wu, Xu Yao, Guan Wang, Xiaohe Liu, Hongfei Chen, Zehua Yang and Xing Zheng* DOI: 10.2174/1570180817999200420115456
Development of Phthalimide-Donepezil Hybrids as Potent Multitarget- Directed Ligands for the Treatment of Alzheimer’s Disease
Volume: 17 Issue: 9 Pp: 1155-1163 Lintao Yu, Jian Shi, Xinfeng Cheng, Keren Wang, Shuang Liu, Wenmin Liu and Zhipei Sang* DOI: 10.2174/1570180817999200420120519
Natural Sesquiterpene Lactones in the Prevention and Treatment of Inflammatory Disorders and cancer: A Systematic Study of this Emerging Therapeutic Approach based on Chemical and Pharmacological Aspect
Volume: 17 Issue: 9 Pp: 1102-1116 Sudip Kumar Mandal, Utsab Debnath, Amresh Kumar, Sabu Thomas, Subhash Chandra Mandal, Manabendra Dutta Choudhury and Partha Palit* DOI: 10.2174/1570180817999200421144007
Discovery of New N-hydrazinecarbothioamide Indazole Hybrids: As Potential Radical (ABTS and DPPH) Scavengers
Volume: 17 Issue: 9 Pp: 1177-1185 Rafaila Rafique, Arshia, Kanwal, Khalid Mohammed Khan*, Sridevi Chigurupati, Uzma Salar, Muhammad Taha and Shahnaz Perveen DOI: 10.2174/1570180817999200424074455
In Silico Design of a Novel Multi-Epitope Peptide Vaccine Against Hepatocellular Carcinoma
Volume: 17 Issue: 9 Pp: 1164-1176 Fatemeh Motamedi Dehbarez, Navid Nezafat and Shirin Mahmoodi* DOI: 10.2174/1570180817999200502030038
Volume: 17 Issue: 9 Pp: 1065-1065 Adriano Mollica DOI: 10.2174/157018081709200911100950
Synthesis, Characterization, Antimicrobial, Anti-tubercular, Antioxidant Activities and Docking Simulations of Derivatives of 2-(pyridin-3-yl)-1Hbenzo[ d]imidazole and 1,3,4-Oxadiazole Analogy
Volume: 17 Issue: 8 Pp: 1047-1059 Shipra Bhati, Vijay Kumar*, Simranjeet Singh and Joginder Singh* DOI: 10.2174/1570180816666191122105313
Anticholinesterase Activity of Cinnamic Acids Derivatives: In Vitro, In Vivo Biological Evaluation, and Docking Study
Volume: 17 Issue: 8 Pp: 965-982 Shahrzad Ghafary, Hamid Nadri, Mohammad Mahdavi, Alireza Moradi, Tahmineh Akbarzadeh, Mohammad Sharifzadeh, Najmeh Edraki, Farshad Homayouni Moghadam and Mohsen Amini* DOI: 10.2174/1570180817666191224094049
Structure-based Virtual Screening Approach for the Discovery of Potent Inhibitors of Aminoglycoside 6'-N-Acetyltransferase Type Ib [AAC(6')-Ib] against K. pneumoniae Infections
Volume: 17 Issue: 8 Pp: 1027-1035 Reaz Uddin*, Bushra Siraj, Sidra Rafi, Syed Sikander Azam and Abdul Wadood DOI: 10.2174/1570180817666200108095912
Biological Evaluation and Molecular Modeling of 3,4-dihydropyrimidine- 2(1H)-one Derivatives as Cytotoxic Agents on Breast Cancer In Vitro
Volume: 17 Issue: 8 Pp: 983-992 Hoda Sharifi, Ahmad Ebadi* and Meysam Soleimani* DOI: 10.2174/1570180817666200203125010
JAK/STAT3 Pathway in Human Intestinal Epithelial Cells During Trefoil Factor 3(TFF3) Mediated Cell Migration
Volume: 17 Issue: 8 Pp: 993-1000 Mengmeng Zhuang, Juan Le, Bo Zhu, Wenwen Zhang, Hao Yan, Pan Zhang, Ting Wang and Yong Sun* DOI: 10.2174/1570180817666200204104420
Lapatinib as a Dual Tyrosine Kinase Inhibitor Unexpectedly Activates Akt in MDA-MB-231 Triple-Negative Breast Cancer Cells promotion: free to download
Volume: 17 Issue: 8 Pp: 1060-1063 Parham Jabbarzadeh Kaboli * and King-Hwa Ling DOI: 10.2174/1570180817666200212125658
Structure-based Drug Design Strategies in the Development of Small Molecule Inhibitors Targeting Bcl-2 Family Proteins open access plus
Volume: 17 Issue: 8 Pp: 943-953 Zhe Yin, Donglin Yang, Jun Wang and Yuequan Jiang* DOI: 10.2174/1570180817666200213114759
Rational Design of Hyper-glycosylated Human Chorionic Gonadotropin Analogs (A Bioinformatics Approach)
Volume: 17 Issue: 8 Pp: 1001-1014 Zahra Nabizadeh, Zarrin Minuchehr* and Ali Akbar Shabani* DOI: 10.2174/1570180817666200225101938
Synthesis, Docking, in silico ADMET and Pharmacological Evaluation of Some N-acetyl Pyrazole and Quinoline Conjugates
Volume: 17 Issue: 8 Pp: 1015-1026 Nargisbano Ayyub Peerzade, Shravan Yegu Jadhav*, Raghunath Bhikaji Bhosale, Amol Anantrao Kulkarni and Bhushan Dnyandeo Varpe DOI: 10.2174/1570180817666200228123347
Studies on the IC50 of Metabolically Stable 1-(3,3-diphenylpropyl)- piperidinyl Amides and Ureas as Human CCR5 Receptor Antagonists Based on QSAR
Volume: 17 Issue: 8 Pp: 1036-1046 Yutao Zhao, Xiaoqian Liu, Jing Ouyang, Yan Wang, Shanyu Xu, Dongdong Tian and Hongzong Si* DOI: 10.2174/1570180817666200320105725
Synthesis of Novel 3-(4-tert-Butylphenyl)-5-Cylopropyl-4H-1,2,4-Triazole Derivatives with Antioxidative and Antimicrobial Activities
Volume: 17 Issue: 8 Pp: 954-964 Nuri Yildirim* DOI: 10.2174/1570180817999200424073524
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Volume: 17 Issue: 8 Pp: 940-942 Saurabh Kumar* DOI: 10.2174/1570180817999200612095513
Volume: 17 Issue: 8 Pp: 939-939 Ahmed Kamal DOI: 10.2174/157018081708200629121931
Facile Synthesis of 6-Phenyl-6h-chromeno [4, 3-b] Quinoline Derivatives using NaHSO4@SiO2 Re-usable Catalyst and Their Antibacterial Activity Study Correlated by Molecular Docking Studies
Volume: 17 Issue: 7 Pp: 929-938 Kancharla Suman, Jyothi Prashanth , Koya Prabhakara Rao*, Madala Subramanyam, Vejendla Anuradha and Mandava Venkata Basaveswara Rao DOI: 10.2174/1570180816666190731115809
Synthesis, Biological Evaluation and Molecular Modeling Studies of Novel C (7) Modified Analogues of Chrysin
Volume: 17 Issue: 7 Pp: 873-883 Pulabala Ramesh, Vankadari Srinivasa Rao, Puchakayala Muralidhar Reddy*, Katragadda Suresh Babu and Mutheneni Srinivasa Rao DOI: 10.2174/1570180816666190913183623
Synthesis of Indolyl Pyrazole Scaffolds as Potential Anti-cancer Agents and their Molecular Modelling Studies
Volume: 17 Issue: 7 Pp: 828-839 Ganga Reddy Gaddam, Pramod Kumar Dubey and Venkata Ramana Reddy Chittireddy* DOI: 10.2174/1570180816666191024103534
Gingerol Derivatives as 14α-demethylase Inhibitors: Design and Development of Natural, Safe Antifungals for Immune-compromised Patients
Volume: 17 Issue: 7 Pp: 918-928 Sweta Sharma and Arpita Yadav* DOI: 10.2174/1570180816666191025105752
Understanding the Binding Mechanism of Antagonist (AZD3293) Against BACE-1: Molecular Insights into Alzheimer’s Drug Discovery
Volume: 17 Issue: 7 Pp: 850-857 Sphelele Sosibo*, Daniel Gyamfi Amoako, Anou Moise Somboro, Darren Delai Sun, Jane Catherine Ngila and Hezekiel Kumalo* DOI: 10.2174/1570180816666191029142640
