Letters in Drug Design & Discovery

Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Volume:9   Issue: 8
Pp: i-iv

DOI: 10.2174/157018012802653001
Published on: 28 August, 2012

A Triphenyltin(IV) Nicotinate Derivative – Synthesis and Toxicity Towards Different Tumour and Normal Cell Lines

Volume:9   Issue: 8
Pp: 737-741
Santiago Gomez-Ruiz, Zeljko Zizak and Goran N. Kaluderovic
DOI: 10.2174/157018012802652976
Published on: 28 August, 2012

Synthesis of Nimesulide Based New Class of Succinimide Analogues: Their Evaluation as Potential Cytotoxic Agents

Volume:9   Issue: 8
Pp: 742-748
Kavitha Kankanala, Vangala Ranga Reddy, Yumnam Priyadarshini Devi, Lakshmi Narasu Mangamoori, Khagga Mukkanti and Sarbani Pal
DOI: 10.2174/157018012802652921
Published on: 28 August, 2012

Synthesis and Study of Antitumor Activity of Artimisinin Glucoside

Volume:9   Issue: 8
Pp: 749-754
Yanrong Ren and Guoping Chen
DOI: 10.2174/157018012802652886
Published on: 28 August, 2012

Quantitative Structural Activity Relationship Studies for In Silico Prediction of In Vitro Cytotoxicity of NSAIDs in Colon Cancer Cell Lines

Volume:9   Issue: 8
Pp: 755-763
Honey Goel, Suresh Thareja, Priyanka Malla, Manoj Kumar and V. R Sinha
DOI: 10.2174/157018012802652895
Published on: 28 August, 2012

Modeling Assisted In Silico Design of Ligand Molecule for DPP IV in Type II Diabetes Mellitus

Volume:9   Issue: 8
Pp: 764-766
S. Amuthalakshmi, A. Anton Smith and R. Manavalan
DOI: 10.2174/157018012802652930
Published on: 28 August, 2012

Synthesis of Ninhydrin Derivatives and their Anticancer, Antimicrobial and Cholinesterase Enzymes Inhibitory Activities

Volume:9   Issue: 8
Pp: 767-774
Raza Murad Ghalib, Rokiah Hashim, Sayed Hasan Mehdi, Othman Sulaiman, P. S. Pereira Silva, Amir Reza Jassbi, Omidreza Firuzi, Fumio Kawamura, Kit-Lam Chan and Vikneswaran Murugaiyah
DOI: 10.2174/157018012802652967
Published on: 28 August, 2012

Semi-Synthesis of Caudatin Glycosides and Study on their Antiproliferative Activities

Volume:9   Issue: 8
Pp: 775-779
Xuefen Tao, Jin Chen and Rusong Zhang
DOI: 10.2174/157018012802652985
Published on: 28 August, 2012

Synthesis and Biological Evaluation of Novel 4-indolyl-5-phenyl(indolyl)- 1,2-dihydropyrazol-3-ones as Glycogen Synthase Kinase-3β (GSK-3β) Inhibitors

Volume:9   Issue: 8
Pp: 780-788
Hong Yin, Fengying Sui, Xinji Yang, Yingying Shangguan and Guojie Song
DOI: 10.2174/157018012802652912
Published on: 28 August, 2012

Synthesis and Antifungal Activity of 3-Substituted-thiochroman-4-one Semicarbazone Derivatives

Volume:9   Issue: 8
Pp: 797-801
Hong-jian Geng, Zhao-bin Xing, Wei Luo, Ling Cong, Xin-yu Li and Chun Guo
DOI: 10.2174/157018012802652903
Published on: 28 August, 2012

In Vitro Activity Against Trypanosoma cruzi and Leishmania chagasi Parasites of 2,4-Diaryl 1,2,3,4-Tetrahydroquinoline Derivatives

Volume:9   Issue: 8
Pp: 802-808
Arnold R. Romero Bohorquez, Patricia Escobar Rivero, Sandra M. Leal and Vladimir V. Kouznetsov
DOI: 10.2174/157018012802652994
Published on: 28 August, 2012

Construction and High Expression of a Recombinant Amino-Proximal HSV-2 Glycoprotein B Polypeptide with Immunogenicity in Escherichia coli

Volume:9   Issue: 8
Pp: 809-814
Xu Ning, Tu Jingjing, Wang Xian Yan and Xu Fang
DOI: 10.2174/157018012802652958
Published on: 28 August, 2012