Letters in Drug Design & Discovery

Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Volume:9   Issue: 6
Pp: i-iv

DOI: 10.2174/157018012800673100
Published on: 17 May, 2012

Arachidonate Cascade in the Intensive Insulin Therapy for Critically Ill Patients with Sepsis: Roles of Prostaglandins on Hyperglycemia-Impaired Immunity

Volume:9   Issue: 6
Pp: 557-567
Tatsurou Yagami, Yasuhiro Yamamoto, Hiromi Kohma and Kenkichi Takase
DOI: 10.2174/157018012800673074
Published on: 17 May, 2012

Anticancer Screening and Structure Activity Relationship Study of Some Semicarbazides and 1,2,4-Triazolin-5-ones

Volume:9   Issue: 6
Pp: 568-572
Monika Pitucha and Jolanta Rzymowska
DOI: 10.2174/157018012800673047
Published on: 17 May, 2012

Synthesis, Anticancer Activities, Antimicrobial Activities and Bioavailability of Berberine-Bile Acid Analogues

Volume:9   Issue: 6
Pp: 573-580
Qingyong Li, Wuna He, Li Zhang, Yuangang Zu, Qiaochu Zhu, Xiaoqiu Deng, Tengfei Zhao, Wenqing Gao and Baoyou Zhang
DOI: 10.2174/157018012800673010
Published on: 17 May, 2012

3D-QSAR Study of Some Heterocyclic Sulfonamide Analogs as hCAII Inhibitors

Volume:9   Issue: 6
Pp: 581-586
Saurabh M. Verma, Arabinda Saha, Rahul Mishra and Kalyan K. Sethi
DOI: 10.2174/157018012800673001
Published on: 17 May, 2012

SAR Study on Reactivators of Ethyl-Paraoxon Inhibited Acetylcholinesterase

Volume:9   Issue: 6
Pp: 587-594
Ondrej Holas, Kamil Musilek, Anna Horova, Veronika Opletalova and Kamil Kuca
DOI: 10.2174/157018012800673083
Published on: 17 May, 2012

QSAR Analysis of Compounds Exhibiting General Anesthetics’ Properties

Volume:9   Issue: 6
Pp: 595-603
Leszek Bober, Piotr Kawczak and Tomasz Baczek
DOI: 10.2174/157018012800673065
Published on: 17 May, 2012

Synthesis of Novel Azetidinone Derivatives as Antitubercular Agents

Volume:9   Issue: 6
Pp: 611-617
M. Himaja, Asif Karigar, M. V. Ramana, D. Munirajasekhar and Mukesh S. Sikarwar
DOI: 10.2174/157018012800673038
Published on: 17 May, 2012

Synthesis, Antibacterial and Antifungal Activities of 3-Amino-5- methyl[1,1'-biphenyl]-2,4-dicarbonitrile Derivatives

Volume:9   Issue: 6
Pp: 618-624
Khalid Mohammed Khan, Waqas Jamil, Nida Ambreen, Afroze Amyn, Summaya Saied, Maria Kanwal, Aqeel Ahmed and Shahnaz Perveen
DOI: 10.2174/157018012800672985
Published on: 17 May, 2012

Synthesis and Biological Activities of Some Novel 2-Amino-(5 or 7-Substituted- 2-Oxoindolin-3-Ylidene) Benzoxazole-5-Carbohydrazide Derivatives

Volume:9   Issue: 6
Pp: 625-632
G. Rajyalakshmi, A. Rama Narsimha Reddy and M. Sarangapani
DOI: 10.2174/157018012800673029
Published on: 17 May, 2012

The Effect of N-4 Substituent on Antibacterial Activity of Novel Hydroxymethyl/Aminomethyl Derivatives of 1,2,4-Triazole-3-thione

Volume:9   Issue: 6
Pp: 633-637
Tomasz Plech, Monika Wujec, Urszula Kosikowska, Anna Malm, Magdalena Barylka, Aleksandra Chalas and Barbara Kapron
DOI: 10.2174/157018012800673056
Published on: 17 May, 2012

Synthesis and Evaluation of Anti-Inflammatory and Antitussive Activity of Hydantion Derivatives

Volume:9   Issue: 6
Pp: 638-642
Haibin Lu, Dejuan Kong, Bin Wu, Shihan Wang and Yongsheng Wang
DOI: 10.2174/157018012800673092
Published on: 17 May, 2012