Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Volume: 9 Issue: 5, June 2012

Graphical Abstracts

Volume:9   Issue: 5
Pp: i-v

DOI: 10.2174/157018012800389278
Published on: 26 April, 2012

Synthesis of Phenanthroindolizidine Alkaloids with an Acyloxy Group at the C3 Position and their Antitumor Activities and Toxicities

Volume:9   Issue: 5
Pp: 447-453
Takashi Ikeda, Takashi Yaegashi, Takeshi Matsuzaki, Ryuta Yamazaki, Satoshi Ueno, Syusuke Hashimoto and Seigo Sawada
DOI: 10.2174/157018012800389232
Published on: 26 April, 2012

Synthesis and Antitumor Activities of 4H-Pyrano[3,2-h]quinoline-3-carbonitrile, 7H-Pyrimido[4',5':6,5]pyrano[3,2-h]quinoline, and 14HPyrimido[4',5':6,5]pyrano[3,2-h][1,2,4]triazolo[1,5-c]quinoline Derivatives

Volume:9   Issue: 5
Pp: 459-470
Abdullah Megbas Al-Ghamdi, Ashraf Hassan Fekry Abd El-Wahab, Hany Mostafa Mohamed and Ahmed Mohamed El-Agrody
DOI: 10.2174/157018012800389331
Published on: 26 April, 2012

An Efficient Synthesis, Characterization and Antimicrobial Screening of N-substituted 2-(piperidin-4-yl)-2H-benzo[d] [1, 2, 3] Triazoles

Volume:9   Issue: 5
Pp: 471-478
Jalapathi Pochampalli, Devender Mandala, Nalla Umapathireddy and Pompu Rajakomuraiah
DOI: 10.2174/157018012800389304
Published on: 26 April, 2012

Design, Synthesis and Evaluation of Chalcone Derivatives as Anti- Inflammatory, Antioxidant and Antiulcer Agents

Volume:9   Issue: 5
Pp: 479-488
Alka N. Choudhary, Arun Kumar and Vijay Juy
DOI: 10.2174/157018012800389368
Published on: 27 April, 2012

Synthesis and Biological Evaluation of Berberine Derivatives as IBS Modulator

Volume:9   Issue: 5
Pp: 489-493
Xin Deng, Xinxin Zhao, Jing Han, Jingjie Wang, Wenlong Huang, Hai Qian and Liang Ge
DOI: 10.2174/157018012800389386
Published on: 27 April, 2012

Deformable Surfactant Vesicles Loading Ammonium Glycyrrhizinate: Characterization and In Vitro Permeation Studies

Volume:9   Issue: 5
Pp: 494-499
Luisa Di Marzio, Carlotta Marianecci, Federica Rinaldi, Sara Esposito and Maria Carafa
DOI: 10.2174/157018012800389287
Published on: 27 April, 2012

CNS Cancer Cell Line Cytotoxicity Profiles of Some 2, 6, 9-Substituted Purines: A Comparative Five-Dose Testing Study

Volume:9   Issue: 5
Pp: 500-504
Tien N. Banh, Nageswara R. Kode and Shashikan Phadtare
DOI: 10.2174/157018012800389241
Published on: 27 April, 2012

Enhanced Oral Bioavailability of Oleanolic Acid in Rats with Phospholipid Complex

Volume:9   Issue: 5
Pp: 505-512
Feng Cao, Yahan Gao, Zhi Yin and Qineng Ping
DOI: 10.2174/157018012800389340
Published on: 27 April, 2012

The Analgesic Activity of 8-(Trifluoromethyl)-1,2,3,4,5-benzopentathiepine- 6-amine and Its Hydrochloride

Volume:9   Issue: 5
Pp: 513-516
Tatyana G. Tolstikova, Alla V. Pavlova, Ekaterina A. Morozova, Tatyana M. Khomenko, Konstantin P. Volcho and Nariman F. Salakhutdin
DOI: 10.2174/157018012800389296
Published on: 27 April, 2012

In Vivo Applied Positively Charged FITC-Labeled Peptide Conjugates Show Artificial Relocation in Frozen Sections

Volume:9   Issue: 5
Pp: 517-526
Alexander Sturzu, Sumbla Sheikh, Ulrich Vogel, Hartmut Echner, Alireza Gharabaghi, Alexander Beck, Thomas Nagele, Ulrike Ernemann and Stefan Heckl
DOI: 10.2174/157018012800389313
Published on: 27 April, 2012

In Silico Methods Applied in Food Chemistry: A Short Review with Bitter and Mutagenic Compounds

Volume:9   Issue: 5
Pp: 527-534
Luciana Scotti, Hamilton Ishiki, Marcelo J.P. Ferreira, Francisco J.B.M. Junior, Vicente de P. Emerenciano, Marcelo S. Silva and Marcus T. Scotti
DOI: 10.2174/157018012800389269
Published on: 27 April, 2012

Small Molecules Antileishmanials: A Review

Volume:9   Issue: 5
Pp: 535-548
Akanksha Kulshrestha, Meenakshi Dhanawat, Nirupam Das and Sushant K. Shrivastava
DOI: 10.2174/157018012800389359
Published on: 27 April, 2012

A Study on the Biological Activity of 2-thioxo-imidazolidin-4-ones

Volume:9   Issue: 5
Pp: 549-555
Sudha Vengurlekar, Rajesh Sharma and Piyush Trivedi
DOI: 10.2174/157018012800389322
Published on: 27 April, 2012



Retraction Notice: Solubilization and Amorphization of Non Steroidal Anti-Inflammatory Drug with Low Molecular Weight Chitosan for a New Guar-Based Colon Delivery Formulation free to download

Volume:9   Issue: 5
Pp: 556-556
Fars K. Alanazi, Nahla S. Barakat and Kadria A. Elkhodairy
DOI: 10.2174/1570180811209050556
Published on: 27 April, 2012