Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Volume: 9 Issue: 4, May 2012

Graphical Abstracts

Volume:9   Issue: 4
Pp: i-v

DOI: 10.2174/157018012799859981
Published on: 26 April, 2012

Heteroarylacetyl Chlorides and Mixed Anhydrides as Intermediates in the Synthesis of Heterocyclic Dronic Acids

Volume:9   Issue: 4
Pp: 345-351
Gyorgy Keglevich, Alajos Grun, Rita Kovacs, Katalin Koos, Beata Szolnoki, Sandor Garadnay, Jozsef Neu, Laszlo Drahos and Istvan Greiner
DOI: 10.2174/157018012799859963
Published on: 26 April, 2012

Optical Studies of the Spectral Properties of Phenothiazines

Volume:9   Issue: 4
Pp: 352-360
Adriana Smarandache, Jette Kristiansen, Jorn B. Christensen and Mihail-Lucian Pascu
DOI: 10.2174/157018012799859918
Published on: 26 April, 2012

Synthesis and In Vivo Antimalarial Activity of Quinoline/Mercaptopurine Conjugates

Volume:9   Issue: 4
Pp: 361-366
Nicolli Bellotti de Souza, Rafael Carvalhaes, Arturene Maria Lino do Carmo, Marcio Jose Martins Alves, Elaine Soares Coimbra, Sonia Maria Neumann Cupolilo, Clarice Abramo and Adilson David Da Silva
DOI: 10.2174/157018012799859990
Published on: 26 April, 2012

QSAR and Docking Studies on Different Series of Histone Deacetylase Inhibitors (HDACIs)

Volume:9   Issue: 4
Pp: 367-378
Yuhong Xiang, Liang Zhang and Zhuoyong Zhang
DOI: 10.2174/157018012799860033
Published on: 26 April, 2012

Design, Synthesis and Antitumor Activity of Novel Cis-Furoquinoline Derivatives

Volume:9   Issue: 4
Pp: 379-388
Jie Li, Shuchen Pei, Yingxi Zhu, Jianbo Wu, Yin Chen, Weiyu Zhang and Yong Wu
DOI: 10.2174/157018012799859909
Published on: 26 April, 2012

A QSAR Study on Some Thiophene Derivatives Acting as Anti-HCV Agents

Volume:9   Issue: 4
Pp: 389-396
Jonish Varshney, Anjana Sharma and Satya P. Gupta
DOI: 10.2174/157018012799859945
Published on: 26 April, 2012

Synthesis and Antitumor Activity of Scopoletin Derivatives

Volume:9   Issue: 4
Pp: 397-401
Jinpei Zhou, Lei Wang, Lijuan Wei, Yu Zheng, Huibin Zhang, Yubin Wang, Peng Cao, Ao Niu, Jing Wang and Yue Dai
DOI: 10.2174/157018012799859972
Published on: 26 April, 2012

Synthesis and Anticonvulsant Activity of Some Novel 2-Methyl Imidazole Derivatives

Volume:9   Issue: 4
Pp: 402-408
Rahul Mishra, Swastika Ganguly, Kalyan Kumar Sethi and Papiya Mitra Mazumder
DOI: 10.2174/157018012799860015
Published on: 26 April, 2012

Synthesis and Anticonvulsant Activity Evaluation of Some 1-alkoxy-4-(1H- 1,2,4-triazol-1-yl)phthalazines

Volume:9   Issue: 4
Pp: 409-414
Shi-Ben Wang, Xian-Qing Deng, Ming-Xia Song and Zhe-Shan Quan
DOI: 10.2174/157018012799860024
Published on: 26 April, 2012

Synthesis of New 2-(N-Arylsulfonylindol-3-yl)-3-aryl-1,3-thiazolidin-4-ones as HIV-1 Inhibitors In Vitro

Volume:9   Issue: 4
Pp: 415-420
Rui-Ge Yang, Liu-Meng Yang, Ya-Zhen Ke, Ning Huang, Rui Zhang, Yong-Tang Zheng and Hui Xu
DOI: 10.2174/157018012799859936
Published on: 26 April, 2012

In Vitro Antioxidant Activity of Some Novel Synthetic Mononuclear Ruthenium (II) Compounds

Volume:9   Issue: 4
Pp: 421-425
Shyam Sunder Anchuri, Sreekanth Thota, Rajeshwar Yerra and Satyavati Dhulipala
DOI: 10.2174/157018012799859927
Published on: 26 April, 2012

The Analysis of the Druggable Families Based on Topological Features in the Protein-Protein Interaction Network

Volume:9   Issue: 4
Pp: 426-430
Qi Yu and Jing-Fei Huang
DOI: 10.2174/157018012799860006
Published on: 26 April, 2012

Synthesis and Antifungal Activity of 1,2,4-triazole Derivatives Containing Cyclopropane Moiety

Volume:9   Issue: 4
Pp: 431-435
Cheng-Xia Tan, Yan-Xia Shi, Jian-Quan Weng, Xing-Hai Liu, Bao-Ju Li and Wei-Guang Zhao
DOI: 10.2174/157018012799859954
Published on: 26 April, 2012

Enhancement of Skin Permeation and Anti-Inflammatory Effect of Indomethacin Using Nanoemulsuion

Volume:9   Issue: 4
Pp: 436-446
Nahla Barakat, Ehab Fouad and Azza Elmedany
DOI: 10.2174/157018012799859891
Published on: 26 April, 2012