Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Volume: 8 Issue: 7, August

Graphical Abstracts

Volume:8   Issue: 7
Pp: i-v

DOI: 10.2174/157018081110807000i
Published on: 01 March, 2012

Computational Analysis of the Apoptotic Activity of a Small Library of Novel Substituted Hydroxy Ureas Designed as Potential Inhibitors of Ribonucleotide Reductase

Volume:8   Issue: 7
Pp: 580-584
Mary P. McCourt, Robert S. Greene, Charles Smith, Haley McClory, Christopher Wirth, Brittany Sumbler, Michelle L. Emery, Brian D. Leskiw, Josef G. Krause, Megan E. McGahan, Shawn Vanio, Michael Jordan, Angela Pericozzi and Ronny Priefer
DOI: 10.2174/157018011796235257
Published on: 01 March, 2012

Classification Structure-Activity Relationship Study of Reverse Transcriptase Inhibitors

Volume:8   Issue: 7
Pp: 585-595
Maria Seyagh, EL Mostapha Mazouz, Andreea Schmitzer, Didier Villemin, Abdellah Jarid and Driss Cherqaoui
DOI: 10.2174/157018011796235248
Published on: 01 March, 2012

Design, Synthesis and Bioactivities of Phenylamino-Pyrimidine Derivatives as Novel Protein Tyrosine Kinase Inhibitors

Volume:8   Issue: 7
Pp: 596-601
Xinfu Hong, Xianzhao Kuang, Guohua Ding, Yilin Liu, Jinlin Liu, Yanjin Zhao and Shuxin Li
DOI: 10.2174/157018011796235202
Published on: 01 March, 2012

Anti HIV-1 Agents 7. Discovery of 1-Hydroxy-4-chloro-9,10-anthraquinone Derivatives as New HIV-1 Inhibitors in Vitro

Volume:8   Issue: 7
Pp: 602-605
Ning Huang, Qin Wang, Liu-Meng Yang, Hui Xu and Yong-Tang Zheng
DOI: 10.2174/157018011796235185
Published on: 01 March, 2012

Synthesis and Evaluation of N-Benzyl-Acridinone Derivatives Induced Apoptosis in Human Liver Cancer Cell-Lines

Volume:8   Issue: 7
Pp: 606-611
Xian-Feng Huang, Yulan-Zhu and Hai-Liang Zhu
DOI: 10.2174/157018011796235176
Published on: 01 March, 2012

Microwave-Assisted Synthesis, Antimicrobial and Cytotoxic Activities of Some 4-Thioxo-Thiazolidine-2-One Derivatives

Volume:8   Issue: 7
Pp: 612-618
Shankar G. Alegaon and Kallanagouda R. Alagawadi
DOI: 10.2174/157018011796235275
Published on: 01 March, 2012

Gene Cloning and Homology Modeling of the 3-Oxoacyl-ACP Synthase from Aeromonas hydrophila for Drug Discovery

Volume:8   Issue: 7
Pp: 619-625
Vijai Singh, Indra Mani and Dharmendra Kumar Chaudhary
DOI: 10.2174/157018011796235293
Published on: 01 March, 2012

Synthesis and Antibacterial Activity of Anacardic Acid Derivatives

Volume:8   Issue: 7
Pp: 626-632
Subhakara Reddy Nallamilli, V. Ravi Kumar, V. Himabindu, B. Ram and Srinivas Rao Aalapati
DOI: 10.2174/157018011796235167
Published on: 01 March, 2012

Synthesis and Study of the Antimicrobial Activity of Novel Tricyclic 2 Hpyrimido [2,1-b]benzothiazoles

Volume:8   Issue: 7
Pp: 633-639
Ravindra M. Kumbhare and Chinna Nagragu
DOI: 10.2174/157018011796235211
Published on: 01 March, 2012

New Quinoline-Based Compounds for Analgesic and Anti-Inflammatory Evaluation

Volume:8   Issue: 7
Pp: 640-648
Rizk Elsayed Khidre, Bakr Fathy Abdel-Wahab and Farid Abdel-Rehem Badria
DOI: 10.2174/157018011796235194
Published on: 01 March, 2012

Solid-Phase Synthesis of Di-N-Acetyl-β-Chitobiosyl NAG-Thiazoline

Volume:8   Issue: 7
Pp: 649-651
Gangliang Huang and Ya Chen
DOI: 10.2174/157018011796235220
Published on: 01 March, 2012

Pharmacophore and 3D-QSAR Studies on 1-Sulfonyl-4-acylpiperazines as Selective Cannabinoid-1 Receptor (CB1R) Inverse Agonists

Volume:8   Issue: 7
Pp: 659-670
Vikas N. Telvekar, Lalit B. Thakur, Prashant B. Jagdhane and Yogesh D. Manohar
DOI: 10.2174/157018011796235284
Published on: 01 March, 2012