Letters in Drug Design & Discovery


Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo

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Volume: 8 Issue: 6, July

Graphical Abstracts

Volume:8   Issue: 6
Pp: i-v

DOI: 10.2174/157018011795906767
Published on: 01 March, 2012

High-Density Lipoprotein Cholesterol-Elevating Effect of a Novel Peroxisome Proliferator-Activated Receptor δ Agonist

Volume:8   Issue: 6
Pp: 496-499
Shogo Sakuma, Tsuyoshi Endo, Takashi Kanda, Hideki Nakamura, Satomi Yamasaki and Tomio Yamakawa
DOI: 10.2174/157018011795906802
Published on: 01 March, 2012

Synthesis and Biological Evaluation of Ezetimibe Analogs as Possible Cholesterol Absorption Inhibitors

Volume:8   Issue: 6
Pp: 500-505
Yubin Wang, Haiqian, Wenlong Huang, Huibin Zhang and Jinpei Zhou
DOI: 10.2174/157018011795906776
Published on: 01 March, 2012

Exploring the Structure Activity Relationships of Imidazole Containing Tetrahydrobenzodiazepines as Farnesyltransferase Inhibitors: A QSAR Study

Volume:8   Issue: 6
Pp: 506-515
Anand Gaurav, Vertika Gautam and Ranjit Singh
DOI: 10.2174/157018011795906758
Published on: 01 March, 2012

Synthesis and SAR Study of Prenylated Xanthone Analogues as HeLa and MDA-MB-231 Cancer Cell Inhibitors

Volume:8   Issue: 6
Pp: 523-528
Chan Kiang Lim, Lai-Yeng Tho, Cheng Hoe Lim, Yang Mooi Lim, Syed Adnan Ali Shah and Jean-Frederic Faizal Weber
DOI: 10.2174/157018011795906820
Published on: 01 March, 2012

Specificity of Three Vasopressin Receptor Antagonists

Volume:8   Issue: 6
Pp: 529-535
Jeremy T. Saks, Barbara Truitt and Menachem Shoham
DOI: 10.2174/157018011795906794
Published on: 01 March, 2012

Anticancer Activity of the Bioreductive and Non-Bioreductive Zerumbone Derivatives

Volume:8   Issue: 6
Pp: 536-543
Siripit Pitchuanchom, Uraiwan Songsiang, Natthida Weerapreeyakul and Chavi Yenjai
DOI: 10.2174/157018011795906811
Published on: 01 March, 2012

Lipid-Lowering Effects of Polymers Derived from Halophenyl Pyrroles

Volume:8   Issue: 6
Pp: 544-549
Bruce S. Burnham, Joshua D. Berkowitz, Zachary Orr, Bryan McCranor, Mardel Cooper, Kurt McCann, Kyle Pillitteri, Jodi Hallback, Lisa-Marie Bergh, Larisa Gofman, Melissa Melendez, Justin M. Holub, Kenzo Morie and Charles E. Carraher
DOI: 10.2174/157018011795906839
Published on: 01 March, 2012

Design, Synthesis and Biological Study of Novel NO-Donor-Caffeic Acid Hybrids as Potential Anti-Atherosclerotic Drug Candidates

Volume:8   Issue: 6
Pp: 550-557
Nian-Guang Li, Rong Wang, Yu-Ping Tang, Zhi-Hao Shi, Bao-Quan Li, Wei Li, Jian-Ping Yang, Zhen-Jiang Wang, Shu-Lin Song, Li-Hua Qian, Li-Juan Yao, Jun-Zuan Xia, Jia Xu, Feng Feng, Da-Wei Qian and Jin-Ao Duan
DOI: 10.2174/157018011795906848
Published on: 01 March, 2012

Novel Coumarin and 4H-Chromene Derivatives Containing 4,5- Dihydropyrazole Moiety: Synthesis and Antibacterial Activity

Volume:8   Issue: 6
Pp: 558-561
Qian-Zhu Li, Xiao-Yan Nie and Jie Liang
DOI: 10.2174/157018011795906857
Published on: 01 March, 2012

New Small-Size Antifungal Peptides: Design, Synthesis and Antifungal Activity

Volume:8   Issue: 6
Pp: 562-567
Adriana D. Garro, Francisco M. Garibotto, Ana M. Rodriguez, Marcela Raimondi, Susana A. Zacchino, Andras Perczel, Csaba Somlai, Botond Penke and Ricardo D. Enriz
DOI: 10.2174/157018011795906785
Published on: 01 March, 2012

A Flow Chemistry Approach to Norcantharidin Analogues

Volume:8   Issue: 6
Pp: 568-574
Mark Tarleton, Kelly A. Young, Elli Unicomb, Siobhann N. McCluskey, Mark J. Robertson, Christopher P. Gordon and Adam McCluskey
DOI: 10.2174/157018011795906730
Published on: 01 March, 2012

Synthesis, Characterization of (E)-N'-(substituted-benzylidene)isonicotinohydrazide Derivatives as Potent Antitubercular Agents

Volume:8   Issue: 6
Pp: 575-579
Manav Malhotra, Rajiv Sharma, Vikramdeep Monga, Aakash Deep, Kapendra Sahu and Abdul Samad
DOI: 10.2174/157018011795906866
Published on: 01 March, 2012