Letters in Drug Design & Discovery


Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo

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Volume: 8 Issue: 1, January

Graphical Abstracts

Volume:8   Issue: 1
Pp: i-v

DOI: 10.2174/157018011793663895
Published on: 01 March, 2012

Binding Modes of 2-Phenylamino-6-oxopurines to Herpes Simplex Virus Thymidine Kinases

Volume:8   Issue: 1
Pp: 1-8
Federico Focher, Andrea Lossani, Andrea Torti, Joseph Gambino and George E. Wright
DOI: 10.2174/157018011793663877
Published on: 01 March, 2012

Design, Synthesis and Pharmacokinetic Evaluation of a Novel Series of Triazole-Based Src Kinase Inhibitors with Anti-proliferative Activity

Volume:8   Issue: 1
Pp: 9-13
Shaojun Chen, Chuansheng Guo, Shiting Shi, Yanyan Shi, Du Fang and Houxing Fan
DOI: 10.2174/157018011793663930
Published on: 01 March, 2012

QSAR Analysis of Isosteviol Derivatives as α-Glucosidase Inhibitors with Element Count and Other Descriptors

Volume:8   Issue: 1
Pp: 14-25
N. S. Hari Narayana Moorthy, Maria J. Ramos and Pedro A. Fernandes
DOI: 10.2174/157018011793663859
Published on: 01 March, 2012

Synthesis and In Vitro Biochemical Evaluation of a Series of Alkyl 6- Aminosulfonyl Naphthanoates as Potential Inhibitors of Human Placental Estrone Sulfatase (ES)

Volume:8   Issue: 1
Pp: 26-31
Chirag K. Patel and Sabbir Ahmed
DOI: 10.2174/157018011793663967
Published on: 01 March, 2012

QSAR Study on 5-Lipoxygenase Activating Protein (FLAP) Inhibitors: The Derivatives of 2,2-Bisaryl-Bicycloheptane

Volume:8   Issue: 1
Pp: 32-43
Brij Kishore Sharma, Pradeep Pilania and Prithvi Singh
DOI: 10.2174/157018011793663903
Published on: 01 March, 2012

Volsurf Descriptors to Analyse Anti-HCV and Cytotoxic Activities of Sesquiterpene Lactones from Asteraceae Family

Volume:8   Issue: 1
Pp: 44-58
Mariane Ballerini Fernandes, Michelle Rossini, Ricardo Stefani, Leoberto Tavares, Vicente de Paulo Emerenciano, Luciana Scotti, Marcelo Sobral da Silva and Marcus Tullius Scotti
DOI: 10.2174/157018011793663868
Published on: 01 March, 2012

Design, Synthesis and Anti Colon Cancer Activity Evaluation of Phosphorylated Derivatives of Lamivudine (3TC)

Volume:8   Issue: 1
Pp: 59-64
Valasani Koteswara Rao, Sanapalli S. Reddy, Balam S. Krishna, Cirandur S. Reddy, Nimmanapalli P. Reddy, Tamatam C.M. Reddy, Chamarthi N. Raju and S. K. Ghosh
DOI: 10.2174/157018011793663921
Published on: 01 March, 2012

Ethyl Gallate as a Combination Drug Can Overcome Resistance in MRSA

Volume:8   Issue: 1
Pp: 65-68
Win Mar Soe, Nyan Lin Myint, Lim Chu Sing, Meena K. Sakharkar, Thean Hock Tang and Kishore R. Sakharkar
DOI: 10.2174/157018011793663949
Published on: 01 March, 2012

Effects of Honey Against the Accumulation of Adipose Tissue and the Increased Blood Pressure on Carbohydrate-Induced Obesity in Rat

Volume:8   Issue: 1
Pp: 69-75
Samanta Romero-Silva, Miguel Angel Martinez R, Laura P. Romero-Romero, Oralia Rodriguez, C. Gerardo Salas G, Nicole Morel, Francisco Javier Lopez-Munoz, Luis Angel Lima-Mendoza and Guadalupe Bravo
DOI: 10.2174/157018011793663912
Published on: 01 March, 2012

Synthesis and Biological Evaluation of Nitric Oxide-releasing Derivatives of Capsaicin as Analgesia Drugs

Volume:8   Issue: 1
Pp: 76-81
Liang Ge, jingjie Wang, Xiaoyan Zhang, Huibin Zhang, Hai Qian, Wenlong Huang and Jinpei Zhou
DOI: 10.2174/157018011793663831
Published on: 01 March, 2012

Synthesis and Evaluation of Antimicrobial Activity of Thiazolidinone Derivatives

Volume:8   Issue: 1
Pp: 82-86
Ravichandran Veerasamy, Harish Rajak, Krishnan Suresh Kumar and Ram Kishore Agrawal
DOI: 10.2174/157018011793663958
Published on: 01 March, 2012

Enhancing Oral Bioavailability of Methylnaltrexone Using an Emulsion Formulation

Volume:8   Issue: 1
Pp: 87-92
Li-Fang Yu, Wei-Gen Lu, Ping Xiang, Li-Li Wang, Li Chen, Ting-Ting Chen, Michael Maojian Gu, Chong-Zhi Wang and Chun-Su Yuan
DOI: 10.2174/157018011793663886
Published on: 01 March, 2012

Discovery of BRM Targeted Therapies: Novel Reactivation of an Anticancer Gene

Volume:8   Issue: 1
Pp: 93-99
Sarah Gramling and David Reisman
DOI: 10.2174/157018011793663840
Published on: 01 March, 2012