Letters in Drug Design & Discovery


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Volume:7   Issue: 4
Pp: i-iv

DOI: 10.2174/157018010790945850

Novel Thiazolidinone Derivatives with an Uncommon Mechanism of Inhibition Towards HIV-1 Reverse Transcriptase

Volume:7   Issue: 4
Pp: 228-234
Eleni Pitta, Emmanuele Crespan, Athina Geronikaki, Giovanni Maga and Alberta Samuele
DOI: 10.2174/157018010790945869

Synthesis and Biological Evaluation of Dihydroisoquinoline-2(1H)- Carbothioamide Derivatives as TRPV1 Antagonists

Volume:7   Issue: 4
Pp: 235-237
Hai Qian, Wei Chen, Xiaoyan Zhang, Huibin Zhang, Jinpei Zhou, Wenlong Huang, Jing Jin and Dongyan Dai
DOI: 10.2174/157018010790945797

Novel 5-Methyl-2,4-Disubstitued-Oxazole Derivatives: Synthesis and Anticancer Activity

Volume:7   Issue: 4
Pp: 238-243
Xin-Hua Liu, Hui-Feng Liu, Chun-Xiou Pan, Jin-Xin Li, Lin-Shan bai, Bao-An Song and Xiang-Feng Chu
DOI: 10.2174/157018010790945878

A Novel Trypsin and α-Chymotrypsin Inhibitor from Maclura pomifera Seeds

Volume:7   Issue: 4
Pp: 244-249
C. M. Lazza, S. A. Trejo, W. D. Obregon, L. G. Pistaccio, N. O. Caffini and L. M.I. Lopez
DOI: 10.2174/157018010790945832

Synthesis, Characterization and Evaluation of Cytotoxicity of New Aminophosphonic Acid Diesters in Human Leukemia Cells

Volume:7   Issue: 4
Pp: 250-259
Avula Balakrishna, Kishore K. Chiruvella, Mudumala V.N. Reddy, Rajesh Reddy, Sandip K. Nayak, Sathees C. Raghavan and Cirandur S. Reddy
DOI: 10.2174/157018010790945841

Novel Nucleophilic Compounds with Oxime Group as Reactivators of Paraoxon-Inhibited Cholinesterases

Volume:7   Issue: 4
Pp: 260-264
Lucie Musilova, Daniel Jun, Jiri Palecek, Vladimir Cirkva, Kamil Musilek, Martin Paar, Martina Hrabinova, Miroslav Pohanka and Kamil Kuca
DOI: 10.2174/157018010790945823

3-Substituted Isocoumarins as Thymidine Phosphorylase Inhibitors

Volume:7   Issue: 4
Pp: 265-268
Khalid Mohammed Khan, Sumbul Ahmed, Sajjad Hussain, Nida Ambreen, Shahnaz Perveen and M. Iqbal Choudhary
DOI: 10.2174/157018010790945805

Three Dimensional Molecular Field Analysis of Thiomorpholine Analogs of TACE Inhibitors Using Receptor Based Alignment

Volume:7   Issue: 4
Pp: 269-274
Malkeet Singh Bahia, Neha Bagga, Rambabu Gundla and Om Silakari
DOI: 10.2174/157018010790945779

Synthesis and Cytotoxic Evaluation of Disubstituted N-Acylhydrazones Pyrazinecarbohydrazide Derivatives

Volume:7   Issue: 4
Pp: 275-280
Marcelle de L. Ferreira, Andre L.P. Candea, Maria das Gracas M. de O. Henriques, Carlos R. Kaiser, Camilo H. da S. Lima and Marcus V.N. de Souza
DOI: 10.2174/157018010790945814

Design, Synthesis and In Vivo Evaluation of Sulfhydryl β-D-Glucose Cholesterols as Ligands for Brain Targeting Liposomes

Volume:7   Issue: 4
Pp: 281-289
Wei Fan, Chengyi Yan, Shan Qian, Nian Yao, Lei Tang and Yong Wu
DOI: 10.2174/157018010790945788

The Development of PDGF Receptor Inhibitors for the Treatment of Glioma: A Review

Volume:7   Issue: 4
Pp: 290-299
Michael A. Badruddoja, Emad Elquza, James Welsh, Laurence Cooke, Abhay Sanan, Baldassrre Stea and Daruka Mahadavan
DOI: 10.2174/157018010790945887

Making Drops in Microencapsulation Processes

Volume:7   Issue: 4
Pp: 300-309
L. Martin-Banderas, A. M. Ganan-Calvo and M. Fernandez-Arevalo
DOI: 10.2174/157018010790945760