Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Volume: 7 Issue: 1, January

Graphical Abstracts

Volume:7   Issue: 1
Pp: v-v

DOI: 10.2174/157018081100701000v
Published on: 01 March, 2012

New Bisquaternary Isoquinolinium Inhibitors of Brain Cholinesterases - Synthesis and Anticholinesterase Activity

Volume:7   Issue: 1
Pp: 1-4
Jiri Binder, Martin Paar, Daniel Jun, Miroslav Pohanka, Martina Hrabinova, Veronika Opletalova and Kamil Kuca
DOI: 10.2174/1570180811007010001
Published on: 01 March, 2012

Design, Synthesis, and Biological Evaluation of 7H-thiazolo[3,2-b]-1,2,4-triazin-7-one Derivatives as Acetylcholinesterase Inhibitors

Volume:7   Issue: 1
Pp: 5-8
Si-Jie Liu, Liu Yang, Xiao-Guang Liu, Ying Luo, Zi-Jian Cao, David Chi Cheong Wan, Huang-Quan Lin and Chun Hu
DOI: 10.2174/157018010789869343
Published on: 01 March, 2012

Synthesis of the Neurotransmitter 4-Aminobutanoic Acid (GABA) from Diethyl Cyanomalonate

Volume:7   Issue: 1
Pp: 9-13
Matthew C. Cook, Ross D. Witherell and Robert L. White
DOI: 10.2174/157018010789869361
Published on: 01 March, 2012

Structure Activity Relationship of Organic Alcohol and Esters for Antidepressant- Like Activity

Volume:7   Issue: 1
Pp: 14-17
Shahnaz Perveen, Arfa Yasmeen, Muhammad Aitmaud Khan, Ahsana Dar, Rehana Jafri and Amir Ahmed
DOI: 10.2174/157018010789869334
Published on: 01 March, 2012

Synthesis and Biological Study of 3-Butyl-1-(2,6-dichlorophenyl)-1H-[1,2,4]triazol- 5(4H)-one Derivatives as Anti-hypertension Drugs

Volume:7   Issue: 1
Pp: 18-22
Yanchun Zhang, Jinpei Zhou, Weihong Pan, Xiaoming Wu and Shuai Wang
DOI: 10.2174/157018010789869370
Published on: 01 March, 2012

The Antisense Oligonucleotides Decrease Expression of the Cellular Prion

Volume:7   Issue: 1
Pp: 23-26
Vitalii V. Stadnyk, Lyudmyla A. Izyumova, Yuriy A. Rzhepetskiy, Chrystyna Ya Mayor and Vasyl V. Vlizlo
DOI: 10.2174/157018010789869299
Published on: 01 March, 2012

Synthesis and Preliminary Biological Activity of Some New Pyrazole Derivatives as Acyclonucleoside Analogues

Volume:7   Issue: 1
Pp: 27-30
Smaail Radi, Souad Salhi and Amal Radi
DOI: 10.2174/157018010789869307
Published on: 01 March, 2012

Synergistic Combinations of Chitosans and Antibiotics in Staphylococcus aureus

Volume:7   Issue: 1
Pp: 31-35
San Tin, Chu Sing Lim, Meena Kishore Sakharkar and Kishore Ramaji Sakharkar
DOI: 10.2174/157018010789869406
Published on: 01 March, 2012

Structure Function Relationships of KTS Disintegrins and Design of Antiangiogenic Drugs

Volume:7   Issue: 1
Pp: 36-40
Olfa Kallech-Ziri, Jose Luis, Ziad Faljoun, Jean-Marc Sabatier, Maxime Lehmann, Mohamed El Ayeb, Naziha Marrakchi and Erwann Loret
DOI: 10.2174/157018010789869325
Published on: 01 March, 2012

Synthesis and Biological Activity of New Triazole Compounds

Volume:7   Issue: 1
Pp: 41-45
Hanane Al Bay, Bouchra Quaddouri, Abdelkarim Guaadaoui, Rachid Touzani, Nour-Eddine Benchat, Abdellah Hamal, Mustafa Taleb, Mohammed Bellaoui and Sghir El Kadiri
DOI: 10.2174/157018010789869352
Published on: 01 March, 2012

Synthesis and In Vitro Evaluation of Novel 1, 2, 4-Triazole Derivatives as Antifungal Agents

Volume:7   Issue: 1
Pp: 46-49
Ganesh R. Kokil, Prarthana V. Rewatkar, Sandeep Gosain, Saurabh Aggarwal, Arunima Verma, Atin Kalra and Suresh Thareja
DOI: 10.2174/157018010789869415
Published on: 01 March, 2012

Physicochemical Interaction Study of Non-Steroidal Anti-Inflammatory Drugs with Dimyristoylphosphatidylethanolamine Liposomes

Volume:7   Issue: 1
Pp: 50-56
Marcela Manrique-Moreno, Jorg Howe, Mario Suwalsky, Patrick Garidel and Klaus Brandenburg
DOI: 10.2174/157018010789869280
Published on: 01 March, 2012

Homology Modelling of Human E1 Ubiquitin Activating Enzyme

Volume:7   Issue: 1
Pp: 57-62
Ghali Brahemi, Angelika M. Burger, Andrew D. Westwell and Andrea Brancale
DOI: 10.2174/157018010789869316
Published on: 01 March, 2012

Preparation of Tiagabine HCl/2-HPβCD Complex Pellets by Extrusion-Spheronization Using Glycerol Monostearate as Pellet-Aid

Volume:7   Issue: 1
Pp: 63-69
Abdussalam Sughir, Malika Lahiani-Skiba and Mohamed Skiba
DOI: 10.2174/157018010789869389
Published on: 01 March, 2012