Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Volume: 6 Issue: 7, October

Solification with Hydrobromic Acid as a Factor Defining the Antiarrhythmic Effect of Lappaconitine Derivatives

Volume:6   Issue: 7
Pp: 475-477
T. G. Tolstikova, A. O. Bryzgalov, I. V. Sorokina, S. A. Osadchii, E. E. Shults, M. P. Dolgikh and M. V. Khvostov
DOI: 10.2174/157018009789108312
Published on: 01 March, 2012

Synthesis and Biological Evaluation of Bridged Analogues of the Platelet Aggregation Inhibitor Trifenagrel

Volume:6   Issue: 7
Pp: 478-486
Magdalena Slusarczyk, Wim M. De Borggraeve, Georges Hoornaert, Koen Robeyns, Luc Van Meervelt, Tongfei Wu, Frederik Deroose and Joannes T.M. Linders
DOI: 10.2174/157018009789108213
Published on: 01 March, 2012

Targeting the Peptide Deformylase of Mycobacterium tuberculosis Leads to Drug Discovery

Volume:6   Issue: 7
Pp: 487-493
Vijai Singh and Pallavi Somvanshi
DOI: 10.2174/157018009789108286
Published on: 01 March, 2012

In Silico Screening of Novel Inhibitors for HPV: A Rational Structure Based Approach (Docking Versus Pharmacophore Model Generation)

Volume:6   Issue: 7
Pp: 494-501
G. Reshmi and M. Radhakrishna Pillai
DOI: 10.2174/157018009789108321
Published on: 01 March, 2012

Microwave-Assisted Solvent-Free Synthesis of N-alkyl Benzotriazole Derivatives: Antimicrobial Studies

Volume:6   Issue: 7
Pp: 502-507
Raghu Ningegowda, C. V. Kavitha, B. S. Priya, S. L. Gaonkar, M. V. Tejesvi, K. S. Rangappa and S. Nanjunda Swamy
DOI: 10.2174/157018009789108222
Published on: 01 March, 2012

New Pyrrole Hydrazones Synthesized and Evaluated In Vitro as Potential Tuberculostatics

Volume:6   Issue: 7
Pp: 508-517
A. Bijev, S. Vladimirova and P. Prodanova
DOI: 10.2174/157018009789108268
Published on: 01 March, 2012

Synthesis and Biochemical Evaluation of a Range of 2-, 3- and 4-Substituted Derivatives of Benzyl Imidazole-Based Compounds as Probes of the Active Site of 17α-hydroxylase/17,20-Lyase (P45017α)

Volume:6   Issue: 7
Pp: 524-530
Sabbir Ahmed, Imran Shahid, Kishore K. Bhatti, Wai-Yee Lee and Caroline P. Owen
DOI: 10.2174/157018009789108295
Published on: 01 March, 2012

On the Synthesis and Anticancer Testing of α,β-Unsaturated Ketones as Analogs of Combretastatin-A4

Volume:6   Issue: 7
Pp: 531-537
Sameer Chavda, Ryan Davis, Amanda Ferguson, Camille Riddering, Kristin Dittenhafer, Hilary Mackay, Balaji Babu, Moses Lee, Adam Siegfried, William Pennington, Miriam Shadfan, Susan L. Mooberry, Bijay K. Mishra and Hari N. Pati
DOI: 10.2174/157018009789108277
Published on: 01 March, 2012

Design, Synthesis, Crystal Structure and Antitumor Activity of A New Ethyl 3-(quinazolin-4-ylamino)-1H-pyrrole-2-carboxylate Derivative

Volume:6   Issue: 7
Pp: 538-541
Youguang Zheng, Xiaoqing Wu, Min Sun, Liuhai Feng, Mingdong Li and Min Ji
DOI: 10.2174/157018009789108240
Published on: 01 March, 2012

Enhanced Brain Targeting of Tegafur Using Novel Lactyl Cholesterol Liposome as a Carrier

Volume:6   Issue: 7
Pp: 542-547
Wei Fan, Xiankun Li, Shan Qian, Shan Wang and Yong Wu
DOI: 10.2174/157018009789108303
Published on: 01 March, 2012

Synthesis, Anticonvulsant Evaluation of 2,3,4,5-Tetrahydro-7-alkoxy-1H-2-benzazepin-1-ones

Volume:6   Issue: 7
Pp: 548-553
Cheng-Xi Wei, Wei Zhang, Zhe-Shan Quan, Rong-Bi Han, Ri-Shan Jiang and Feng-Yu Piao
DOI: 10.2174/157018009789108231
Published on: 01 March, 2012