Letters in Drug Design & Discovery


Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo

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Volume: 5 Issue: 4, June

Drug Design Should Involve Consideration of Environmental Risk and Hazard

Volume:5   Issue: 4
Pp: 232-235
B. Gunnarsson and A. Wennmalm
DOI: 10.2174/157018008784619942
Published on: 01 March, 2012

Design and Synthesis of Carbohydrate Derivatives for Antagonistic Activity at Muscarinic Receptor

Volume:5   Issue: 4
Pp: 236-242
David R. da Rocha, Vitor F. Ferreira, Lucia Garcez-do-Carmo and Wilson C. Santos
DOI: 10.2174/157018008784619870
Published on: 01 March, 2012

Schiff Bases of Istain: Potential Anti-Leishmanial Agents

Volume:5   Issue: 4
Pp: 243-249
Khalid Mohammed Khan, Uzma Rasool Mughal, Samreen, Shahnaz Perveen and Muhammad Iqbal Choudhary
DOI: 10.2174/157018008784619915
Published on: 01 March, 2012

Synthesis of Medicinally Important N-Trimethylene Dipiperidine Sulfonamides and Carboxamides Containing a Substituted Benzophenone Moiety - An Antibacterial Agents

Volume:5   Issue: 4
Pp: 250-260
Mallappanahally Kambappa Vinaya, Hanuma Naika Raja Naika, Channapille Koppal Siddegowda Ananda Kumar, Salekoppal Boregowda Benaka Prasad, Siddappa Chandrappa, Somasagara Ramanna Ranganatha, Venkatarangaiah Krishna and Kanchugarakoppal Subbegowda Rangappa
DOI: 10.2174/157018008784619951
Published on: 01 March, 2012

Synthesis and Anticancer Activity of Phthalimido and Naphthalimido Substituted Dihydropyrimidone Conjugates

Volume:5   Issue: 4
Pp: 261-270
Ahmed Kamal, S. F. Adil, Jaki R. Tamboli, B. Siddardha and U. S.N. Murthy
DOI: 10.2174/157018008784619933
Published on: 01 March, 2012

Selective Androgen Receptor Modulators Antagonize Apolipoprotein E4-Induced Cognitive Impairments open access plus

Volume:5   Issue: 4
Pp: 271-276
Summer Acevedo, Luis Gardell, Stefania Risso Bradley, Fabrice Piu and Jacob Raber
DOI: 10.2174/157018008784619898
Published on: 01 March, 2012

Antimalarial Activity of 2,4-Diaminopyrimidines

Volume:5   Issue: 4
Pp: 277-280
J. Morgan, R. Haritakul and P. A. Keller
DOI: 10.2174/157018008784619843
Published on: 01 March, 2012

A Quantitative Structure-Activity Relationship Study on a Novel Series of Hydroxamic Acid Analogs Acting as Matrix Metalloproteinase Inhibitors

Volume:5   Issue: 4
Pp: 281-285
S. P. Gupta, Priyanka Bagaria and V. S.A. Kumar Satuluri
DOI: 10.2174/157018008784619852
Published on: 01 March, 2012

Synthesis of 5-Arylidene Barbiturates: A Novel Class of DPPH Radical Scavengers

Volume:5   Issue: 4
Pp: 286-291
Khalid M. Khan, Muhammad Ali, Asma Ajaz, Shahnaz Perveen, M. Iqbal Choudhary and Atta-ur-Rahman
DOI: 10.2174/157018008784619889
Published on: 01 March, 2012

Phenylpyazoleanilides as Potent Inhibitor of IL-15 Dependent T Cell Proliferation. Part 2: Discovery of a New Drug Candidate, Y-320 open access plus

Volume:5   Issue: 4
Pp: 292-296
Hiroyuki Ushio, Seigo Ishibuchi, Kunitomo Adachi, Kouichi Oshita and Kenji Chiba
DOI: 10.2174/157018008784619861
Published on: 01 March, 2012

Modulation by Dopaminergic System of Morphine Withdrawal: In Vitro Evidences

Volume:5   Issue: 4
Pp: 297-301
A. Capasso
DOI: 10.2174/157018008784619906
Published on: 01 March, 2012

A Novel Strategy to Manage Tolerance to Lamotrigine in Bipolar II Depression

Volume:5   Issue: 4
Pp: 302-302
V. Sharma and C. Corpse
DOI: 10.2174/157018008784619924
Published on: 01 March, 2012

Tetrahydroisoquinoline-Related Modulators of Multidrug Resistance in Cancer

Volume:5   Issue: 4
Pp: 303-306
Yu Li, Hui Bin Zhang, Wen Long Huang, Xia Zhen and Yun Man Li
DOI: 10.2174/157018008784619834
Published on: 01 March, 2012