Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Volume: 4 Issue: 6, September

Inhibition of Human Leucocyte Elastase by Novel Thieno-1,3-oxazin-4-ones and Thieno-1,3-thioxazin-4-ones

Volume:4   Issue: 6
Pp: 386-393
N.A. Santagati, L. Salerno, C. Di Giacomo, L. Vanella and S. Ronsisvalle
DOI: 10.2174/157018007781387764
Published on: 01 March, 2012

Synthesis and In Vitro Biochemical Evaluation of a Series of Cycloalkyl Esters of 4-Sulfamoylated Benzoic Acid as Inhibitors of Estrone Sulfatase (ES)

Volume:4   Issue: 6
Pp: 399-403
Caroline P. Owen, Chirag K. Patel, Tim Cartledge and Sabbir Ahmed
DOI: 10.2174/157018007781387845
Published on: 01 March, 2012

Synthesis and Anti-HSV-1 Activity of 1,4-dihydro-4-oxoquinoline Ribonucleosides

Volume:4   Issue: 6
Pp: 404-409
Carla Veronica B. dos S. Canuto, Claudia R. B. Gomes, Isakelly P. Marques, Leticia V. Faro, Fernanda da Costa Santos, Izabel Christina de P. P. Frugulhetti, Thiago M. L. e Souza, Anna C.Cunha, Gilberto A. Romeiro, Vitor F. Ferreira and Maria Cecilia B.V.de Souza
DOI: 10.2174/157018007781387818
Published on: 01 March, 2012

Classification and Prediction of Tripeptides Inhibiting HIV-1 Tat/TAR-RNA Interaction Using a Self-Organizing Map

Volume:4   Issue: 6
Pp: 410-416
A. Givehchi, V. Ludwig, O. Boden, A. Krebs, U. Scheffer, M. Gobel and G. Schneider
DOI: 10.2174/157018007781387791
Published on: 01 March, 2012

Structure-Based Quantitative Structure Activity Relationship Analysis of Omuralide Analogs in the 20S Proteasome: A Covalent Inhibitor COMBINE Study

Volume:4   Issue: 6
Pp: 417-421
Jenna L. Wang, Apurba Datta and Gerald H. Lushington
DOI: 10.2174/157018007781387809
Published on: 01 March, 2012

The Molecular Basis of COX-2 Versus COX-1 Selectivity of Lumiracoxib by Molecular Docking Studies

Volume:4   Issue: 6
Pp: 422-425
Celia M. Correa, Andre F. de Paula, Gilberto M.S. da Silva, Carlos M.R. Sant'Anna, Carlos A. M. Fraga and Eliezer J. Barreiro
DOI: 10.2174/157018007781387737
Published on: 01 March, 2012

A Cationic Liposomal Vincristine Formulation with Improved Vincristine Retention, Extended Circulation Lifetime and Increased Anti-Tumor Activity

Volume:4   Issue: 6
Pp: 426-433
Murray S. Webb, Nancy L. Boman, Dana Masin, Donald Yapp, Euan Ramsay, Gigi N.C. Chiu, Pieter R. Cullis and Marcel B. Bally
DOI: 10.2174/157018007781387782
Published on: 01 March, 2012

Isoform-Selective Regulation of Adenylyl Cyclase by Forskolin Derivatives:Prediction of Selectivity by Computer-Based Analysis

Volume:4   Issue: 6
Pp: 434-441
Haruki Eguchi, Kousaku Iwatsubo and Yoshihiro Ishikawa
DOI: 10.2174/157018007781387755
Published on: 01 March, 2012

Preparation and Biological Activities of Heteroarotinoids

Volume:4   Issue: 6
Pp: 442-445
Akimori Wada, Yukari Mizuguchi, Hiromi Miyake, Miki Niihara, Masayoshi Ito, Kimie Nakagawa and Toshio Okano
DOI: 10.2174/157018007781387827
Published on: 01 March, 2012

Lamotrigine as an Effective Treatment for Behavioral Disorders

Volume:4   Issue: 6
Pp: 446-452
Rita Moretti, Paola Torre, Cristina Vilotti and Rodolfo M. Antonello
DOI: 10.2174/157018007781387836
Published on: 01 March, 2012

Release Kinetics of Ampicillin, Biocompatibility Tests with a Fibroblast Strain of a Zirconia Gel Glass

Volume:4   Issue: 6
Pp: 453-459
M. Catauro, M.G. Raucci and M.A. Continenza
DOI: 10.2174/157018007781387746
Published on: 01 March, 2012