Letters in Drug Design & Discovery


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Quality Initiatives in Drug Discovery: Swim Dont Sink

Volume:3   Issue: 5
Pp: 286-288
S. G. Volsen, M. G. Parry and M. Masson
DOI: 10.2174/157018006777574195

Design and Discovery of Novel, Potent Pyrazinone-Based Thrombin Inhibitors with a Solubilizing Amino P1-P2-Linker

Volume:3   Issue: 5
Pp: 289-292
S. Bulat, S. Bosio, M. A. Papadopoulos, S. Cerezo-Galvez, E. Grabowski, C. Rosenbaum, V. G. Matassa, I. Ott, G. Metz, J. Schamberger, R. Sekul and A. Feurer
DOI: 10.2174/157018006777574203

Target Structure-based Modeling of the Glutamate Transporter Pharmacophore

Volume:3   Issue: 5
Pp: 293-297
A. Simon, A. Bencsura and J. Kardos
DOI: 10.2174/157018006777574230

Novel Benzimidazole Derivatives as Selective CB2 Inverse Agonists

Volume:3   Issue: 5
Pp: 298-303
D. Page, M.-C. Brochu, H. Yang, W. Brown, S. St-Onge, E. Martin and D. Salois
DOI: 10.2174/157018006777574177

Design, Synthesis and Biological Evaluation of Novel Curcumin Analogues as Anti-Neoplastic Agents

Volume:3   Issue: 5
Pp: 304-310
Amitabh Jha, Jin Zhao, T. Stanley Cameron, Erik De Clercq, Jan Balzarini, Elias K. Manavathu and James P. Stables
DOI: 10.2174/157018006777574131

Synthesis of Piperazinephen-1-ylethylamines as Potent and Selective Antagonists of the Human Melanocortin-4 Receptor

Volume:3   Issue: 5
Pp: 311-315
Fabio C. Tucci, Joe A. Tran, Wanlong Jiang, Joseph Pontillo, Dragan Marinkovic, Nicole S. White, Melissa Arellano, Beth A. Fleck, Jenny Wen, John Saunders, Alan C. Foster and Chen Chen
DOI: 10.2174/157018006777574249

Cytotoxic and COX-2 Inhibition Properties of Hydroxycinnamic Derivatives

Volume:3   Issue: 5
Pp: 316-320
M. Paula M. Marques, Fernanda Borges, Joana Sousa, Rita Calheiros, Jorge Garrido, Alexandra Gaspar, Carmen Diniz and Paula Fresco
DOI: 10.2174/157018006777574212

Design, Synthesis and Initial In Vitro Evaluation of Novel Prodrugs for the Treatment of Cystinosis

Volume:3   Issue: 5
Pp: 336-345
R. J. Anderson, D. Cairns, W. A. Cardwell, M. Case, P. W. Groundwater, A. G. Hall, L. Hogarth, A. L. Jones, O. Meth-Cohn and P. Suryadevara
DOI: 10.2174/157018006777574258

The Cardiovascular Properties of Some Amide Derivatives of Pyrimidin-8-on[2,1-f]theophylline-9- Alkylcarboxylic Acids

Volume:3   Issue: 5
Pp: 346-350
A. Zagorska, O. Fhid, M. Pawlowski, B. Filipek and M. Zygmunt
DOI: 10.2174/157018006777574159

Homocysteine and Folate Therapy in Dialysis Patients

Volume:3   Issue: 5
Pp: 351-355
Marco Righetti
DOI: 10.2174/157018006777574140

Erratum promotion: free to download

Volume:3   Issue: 5
Pp: 356-356

DOI: 10.2174/157018006777574186