Letters in Drug Design & Discovery


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Rational Design of the New Antihypertensive I1-Receptor Ligand 2-(2- Biphenyl-2-yl-1-methyl-ethyl)-4,5-dihydro-1H-imidazole

Volume:2   Issue: 8
Pp: 571-578
F. Gentili, P. Bousquet, A. Carrieri, J. Feldman, F. Ghelfi, M. Giannella, A. Piergentili, W. Quaglia, C. Vesprini and M. Pigini
DOI: 10.2174/157018005774717325

Docking Study, Synthesis and SAH-Hydrolase Inhibitory Activity of LAdeninylalanine and Related Analogues

Volume:2   Issue: 8
Pp: 579-583
Nicolas Floquet, Samuel Leroy, Murielle Muzard, Georges Guillerm and Jean-Bernard Behr
DOI: 10.2174/157018005774717262

Discovery of Thrombin Inhibitor Fragments from Chemical Microarray Screening

Volume:2   Issue: 8
Pp: 590-594
Thomas Neumann, Hans-Dieter Junker, Oliver Keil, Klaus Burkert, Holger Ottleben, Jurgen Gamer, Renate Sekul, Holger Deppe, Achim Feurer, Dirk Tomandl and Gunther Metz
DOI: 10.2174/157018005774717343

Identification of Privileged Scaffolds from a Diversified Chemical Library forβ-Secretase Inhibition

Volume:2   Issue: 8
Pp: 595-600
Nicolas Pietrancosta, Gilles Quelever, Cedrik Garino, Younes Laras, Stephane Burlet and Jean-Louis Kraus
DOI: 10.2174/157018005774717352

Synthesis and Biological Evaluation of 1,2,4-Triazolo[2,3-a]pyrrole Derivatives as Alpha-4 ( α4) Integrin Antagonists

Volume:2   Issue: 8
Pp: 601-605
Edward C. Lawson, William A. Kinney, Rosemary J. Santulli, Carol M. Fisher, Bruce P. Damiano and Bruce E. Maryanoff
DOI: 10.2174/157018005774717280

Szeged Index - Applications for Drug Modeling&#

Volume:2   Issue: 8
Pp: 606-624
Padmakar V. Khadikar, Sneha Karmarkar, Vijay K. Agrawal, Jyoti Singh, Anjali Shrivastava, Istvan Lukovits and Mircea V. Diudea
DOI: 10.2174/157018005774717334

Initial Structure-Activity Relationships for a Caprolactam-based Series of Neutral Factor Xa Inhibitors: Lead Identification

Volume:2   Issue: 8
Pp: 625-630
Gregory S. Bisacchi, Philip D. Stein, Jack Z. Gougoutas, Karen S. Hartl, R. Michael Lawrence, Eddie Liu, Andrew Pudzianowski, William A. Schumacher, Doree Sitkoff, Thomas E. Steinbacher, James Sutton, Zhaoxiao Zhang and Steven M. Seiler
DOI: 10.2174/157018005774717316

Structure Based Design of Inhibitors of Aspartic Protease of HIV-1

Volume:2   Issue: 8
Pp: 638-646
V. Frecer, A. Jedinak, A. Tossi, F. Berti, F. Benedetti, D. Romeo and S. Miertus
DOI: 10.2174/157018005774717307