Letters in Drug Design & Discovery


Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo

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Volume: 2 Issue: 7, November

Inhibitors of Hepatitis C Virus NS3.4A Protease: P2 Proline Variants

Volume:2   Issue: 7
Pp: 497-502
Luc J. Farmer, Shawn D. Britt, Kevin M. Cottrell, John J. Court, Lawrence F. Courtney, David D. Deininger, Cynthia A. Gates, Scott L. Harbeson, Kai Lin, Chao Lin, Yu- P. Luong, John P. Maxwell, Janos Pitlik, B. G. Rao, Wayne C. Schairer, John A. Thomson, Roger D. Tung, John H. Van Drie, Yunyi Wei and Robert B. Perni
DOI: 10.2174/157018005774479203
Published on: 01 March, 2012

Ximelagatran: An Oral Direct Thrombin Inhibitor for Anticoagulant Therapy

Volume:2   Issue: 7
Pp: 503-506
Marco L. Rossi, Dennis Zavalloni, Guido Belli and Patrizia Presbitero
DOI: 10.2174/157018005774479168
Published on: 01 March, 2012

Design of Selective Inhibitors of Tyrosine Kinase 2

Volume:2   Issue: 7
Pp: 507-515
Kristin Tondel and Finn Drablos
DOI: 10.2174/157018005774479104
Published on: 01 March, 2012

Selectivity of SB203580, SB202190 and Other Commonly Used p38 Inhibitors: Profiling Against a Multi-Enzyme Panel

Volume:2   Issue: 7
Pp: 516-521
Jacqueline L. Norris, Kevin P. Williams, William P. Janzen, C. N. Hodge, Leonard J. Blackwell and Ioana G. Popa-Burke
DOI: 10.2174/157018005774479159
Published on: 01 March, 2012

Synthesis and Anti-Breast Cancer Activity of Tetrasubstituted Pyrrole Derivatives

Volume:2   Issue: 7
Pp: 529-532
Jose M. Padron, David Tejedor, Alicia Santos-Exposito, Fernando Garcia-Tellado, Jesus Villar and Victor S. Martin
DOI: 10.2174/157018005774479122
Published on: 01 March, 2012

New Peptidic GnRH Antagonists Offer a Broad Range of Therapeutic Applications

Volume:2   Issue: 7
Pp: 533-536
Engel J.B, Diedrich K and Honig A
DOI: 10.2174/157018005774479195
Published on: 01 March, 2012

Synthesis and Evaluation of Some 16-Benzylidene Substituted 3,17- Dioximino Androstene Derivatives as Anticancer Agents

Volume:2   Issue: 7
Pp: 537-545
Sonal Dubey, Poonam Piplani and Dharam P. Jindal
DOI: 10.2174/157018005774479186
Published on: 01 March, 2012

Design Features that Affect Psychopharmacology Trials

Volume:2   Issue: 7
Pp: 546-550
Arif Khan and Kelly Schwartza
DOI: 10.2174/157018005774479140
Published on: 01 March, 2012

A Review of the Regulatory Role of Nicotinamide on Pro- and Anti-apoptotic Proteins in Neuronal Cells

Volume:2   Issue: 7
Pp: 551-557
S. K. Mukherjee, M. Sonee and J. D. Adams Jr
DOI: 10.2174/157018005774479177
Published on: 01 March, 2012

L-Dopa Related Hyperhomocysteinemia: A Possible Mediator of Toxicity?

Volume:2   Issue: 7
Pp: 558-562
Stefano Zoccolella, Giovanni Iliceto, Michele deMari, Giovanni Defazio, Paolo Livrea and Paolo Lamberti
DOI: 10.2174/157018005774479113
Published on: 01 March, 2012

Synthesis and Anti-Mycobacterial Activity of N-[(E)-(Disubstituted- Phenyl)Methylidene]Isonicotino-Hydrazide Derivatives

Volume:2   Issue: 7
Pp: 563-566
Ivan N. Junior, Maria C. S. Lourenco, Maria das Gracas M. O. Henriques, Barbara Ferreira, Thatyana R. A. Vasconcelos, Monica A. Peralta, Pedro S. M. de Oliveira, Solange M. S. V. Wardell and Marcus V. N. de Souza
DOI: 10.2174/157018005774479131
Published on: 01 March, 2012

Interaction of Furosemide with the Human Sodium-Dependent Dicarboxylate Transporter (hNaDC-3)

Volume:2   Issue: 7
Pp: 567-570
Ingo Muller, Yohannes Hagos, Gerhard Burckhardt and Birgitta C. Burckhardt
DOI: 10.2174/157018005774479087
Published on: 01 March, 2012