Letters in Drug Design & Discovery

Editor-in-Chief

Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
(Italy)

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Volume: 2 Issue: 5, August

Graphical Abstracts

Volume:2   Issue: 5
Pp: iii-iii

DOI: 10.2174/1570180810502050iii
Published on: 01 March, 2012

Symmetrical Derivatives with Nitrogenated Functions as Cytotoxic Agents and Apoptosis Inducers

Volume:2   Issue: 5
Pp: 341-354
Carmen Sanmartin, Elena Ardaiz, Lucia Cordeu, Elena Cubedo, Jesus Garcia-Foncillas, Maria Font and Juan Antonio Palop
DOI: 10.2174/1570180054405794
Published on: 01 March, 2012

Investigation of Tubulin Polymerizing Agents: Synthesis of Substituted Cyclooctatrienes as a Possible Taxoid Framework

Volume:2   Issue: 5
Pp: 355-363
A. Zand, P. Wagner, J. Song and J. Tischler
DOI: 10.2174/1570180054405776
Published on: 01 March, 2012

Identification of Sanguinarine as a Novel HIV Protease Inhibitor from High-Throughput Screening of 2,000 Drugs and Natural Products with a Cell-Based Assay

Volume:2   Issue: 5
Pp: 364-371
Ting-Jen Cheng, David S. Goodsell and Chen-Chen Kan
DOI: 10.2174/1570180054405811
Published on: 01 March, 2012

Natural Endocannabinoid Derivatives as Templates for the Development of FAAH Inhibitors

Volume:2   Issue: 5
Pp: 372-376
Enrico Dainese and Mauro Maccarrone
DOI: 10.2174/1570180054405802
Published on: 01 March, 2012

Indirubin-3-Aminooxy-Acetate Inhibits Glycogen Phosphorylase by Binding at the Inhibitor and the Allosteric Site. Broad Specificities of the Two Sites

Volume:2   Issue: 5
Pp: 377-390
Magda N. Kosmopoulou, Demetres D. Leonidas, Evangelia D. Chrysina, Gerhard Eisenbrand and Nikos G. Oikonomakos
DOI: 10.2174/1570180054405839
Published on: 01 March, 2012

New Perspectives in the Modulation of the Eicosanoid Cascade in Inflammation

Volume:2   Issue: 5
Pp: 391-402
J. Claria and M. Lopez-Parra
DOI: 10.2174/1570180054405730
Published on: 01 March, 2012

Experimental Mouse Models of Thrombosis Optimized for Drug Discovery and Development

Volume:2   Issue: 5
Pp: 403-411
X. Wang
DOI: 10.2174/1570180054405785
Published on: 01 March, 2012

M2000, Foundation of a New Generation Among NSAIDs

Volume:2   Issue: 5
Pp: 412-423
A. Mirshafiey, B. Rehm, S. Cuzzocrea, H. Matsuo, E. Mazzon, S. Nakane, C- S. Koh and S. Miyoshi
DOI: 10.2174/1570180054405767
Published on: 01 March, 2012

Aromatic Polycationic Molecules with Restricted Conformations: An Alternative Approach to Antiherpes Agents

Volume:2   Issue: 5
Pp: 424-427
Andrew Tsotinis, Margarita Vlachou, Andreas Eleutheriades, Peter J. Garratt, Ashley J. Ibbett, Yiu-Fai Ng, Christophe Pannecouque, Myriam Witvrouw and Erik De Clercq
DOI: 10.2174/1570180054405758
Published on: 01 March, 2012

Erratum

Volume:2   Issue: 5
Pp: 428-428

DOI: 10.2174/1570180054405820
Published on: 01 March, 2012